Affinity DataEC50: 8.75E+3nMAssay Description:Inhibition of cPEPCK in rat H4IIE cells assessed as effect on glucose productionMore data for this Ligand-Target Pair
Affinity DataEC50: 4.70E+3nMAssay Description:Inhibition of cPEPCK in rat H4IIE cells assessed as effect on glucose productionMore data for this Ligand-Target Pair
Affinity DataEC50: 8.20E+3nMAssay Description:Inhibition of cPEPCK in rat H4IIE cells assessed as effect on glucose productionMore data for this Ligand-Target Pair
Affinity DataEC50: 5.50E+3nMAssay Description:Inhibition of cPEPCK in rat H4IIE cells assessed as effect on glucose productionMore data for this Ligand-Target Pair
Affinity DataEC50: 3.40E+3nMAssay Description:Inhibition of cPEPCK in rat H4IIE cells assessed as effect on glucose productionMore data for this Ligand-Target Pair
Affinity DataEC50: 5.57E+3nMAssay Description:Inhibition of cPEPCK in rat H4IIE cells assessed as effect on glucose productionMore data for this Ligand-Target Pair
Affinity DataEC50: 3.97E+3nMAssay Description:Inhibition of cPEPCK in rat H4IIE cells assessed as effect on glucose productionMore data for this Ligand-Target Pair
Affinity DataEC50: 8.60E+3nMAssay Description:Inhibition of cPEPCK in rat H4IIE cells assessed as effect on glucose productionMore data for this Ligand-Target Pair
Affinity DataEC50: 2.17E+3nMAssay Description:Inhibition of cPEPCK in rat H4IIE cells assessed as effect on glucose productionMore data for this Ligand-Target Pair
Affinity DataKi: 3.70E+4nM ΔG°: -25.3kJ/moleT: 2°CAssay Description:OAA/PEP binding site. When the enzyme was assayed in the direction of PEP →OAA, the standard reaction mixture contained 50 mM HEPES (pH 7.5), 2...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKi: 3.70E+4nMAssay Description:The inhibition of H477R PEPCK by β-sulfopyruvate (βSP), oxalate, and GMPPCP was conducted in the direction of PEP synthesis (OAA → PE...More data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nM ΔG°: -24.8kJ/moleT: 2°CAssay Description:OAA/PEP binding site. The activity of PEPCK in the direction from OAA to PEP was assayed with 50 mM HEPES (pH 7.5), 10 mM DTT, 4 mM MgCl2, 0.5 mM GTP...More data for this Ligand-Target Pair
Affinity DataKi: 8.30E+4nM ΔG°: -23.3kJ/moleT: 2°CAssay Description:OAA/PEP binding site. When the enzyme was assayed in the direction of PEP →OAA, the standard reaction mixture contained 50 mM HEPES (pH 7.5), 2...More data for this Ligand-Target Pair
Affinity DataKi: 8.30E+4nM ΔG°: -23.3kJ/moleT: 2°CAssay Description:Allosteric binding site. When the enzyme was assayed in the direction of PEP →OAA, the standard reaction mixture contained 50 mM HEPES (pH 7.5)...More data for this Ligand-Target Pair
Affinity DataKi: 1.21E+5nM ΔG°: -22.4kJ/moleT: 2°CAssay Description:Allosteric binding site. The activity of PEPCK in the direction from OAA to PEP was assayed with 50 mM HEPES (pH 7.5), 10 mM DTT, 4 mM MgCl2, 0.5 mM ...More data for this Ligand-Target Pair
Affinity DataKi: 1.50E+5nMAssay Description:The inhibition of H477R PEPCK by β-sulfopyruvate (βSP), oxalate, and GMPPCP was conducted in the direction of PEP synthesis (OAA → PE...More data for this Ligand-Target Pair
Affinity DataKi: 1.80E+5nM ΔG°: -21.4kJ/moleT: 2°CAssay Description:Allosteric binding site. When the enzyme was assayed in the direction of PEP →OAA, the standard reaction mixture contained 50 mM HEPES (pH 7.5)...More data for this Ligand-Target Pair
Affinity DataKi: 2.89E+5nMAssay Description:The inhibition of H477R PEPCK by β-sulfopyruvate (βSP), oxalate, and GMPPCP was conducted in the direction of PEP synthesis (OAA → PE...More data for this Ligand-Target Pair
Affinity DataKi: 4.41E+5nMAssay Description:The inhibition of H477R PEPCK by β-sulfopyruvate (βSP), oxalate, and GMPPCP was conducted in the direction of PEP synthesis (OAA → PE...More data for this Ligand-Target Pair
Affinity DataKi: 6.96E+5nMAssay Description:The inhibition of H477R PEPCK by β-sulfopyruvate (βSP), oxalate, and GMPPCP was conducted in the direction of PEP synthesis (OAA → PE...More data for this Ligand-Target Pair
