Compile Data Set for Download or QSAR
Report error Found 500 of affinity data for UniProtKB/TrEMBL: P07195
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50420178(GUANIDINE)
Affinity DataEC50:  6.24E+8nMAssay Description:Binding affinity full length human N-terminal His6-tagged LDH-H L3A mutant expressed in Escherichia coli Rosetta (DE3) assessed as tetrameric disrupt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50527803(CHEMBL4557180)
Affinity DataKd:  1.10E+4nMAssay Description:Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50527804(CHEMBL4453053)
Affinity DataKd:  1.78E+6nMAssay Description:Binding affinity to full length human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) measured after 5 mins by Red-NHS fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50420178(GUANIDINE)
Affinity DataEC50:  1.01E+9nMAssay Description:Binding affinity full length human N-terminal His6-tagged LDH-H E5A mutant expressed in Escherichia coli Rosetta (DE3) assessed as tetrameric disrupt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50420178(GUANIDINE)
Affinity DataEC50:  9.54E+8nMAssay Description:Binding affinity full length human N-terminal His6-tagged LDH-H K6A mutant expressed in Escherichia coli Rosetta (DE3) assessed as tetrameric disrupt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50527805(CHEMBL4440124)
Affinity DataKd:  1.05E+6nMAssay Description:Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50527806(CHEMBL4437918)
Affinity DataKd:  6.70E+4nMAssay Description:Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50527807(CHEMBL4525659)
Affinity DataKd:  7.87E+5nMAssay Description:Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50527808(CHEMBL4582140)
Affinity DataKd:  3.98E+5nMAssay Description:Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50527809(CHEMBL4456178)
Affinity DataKd:  2.50E+4nMAssay Description:Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50527810(CHEMBL4532326)
Affinity DataKd:  1.13E+5nMAssay Description:Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50527811(CHEMBL4450669)
Affinity DataKd:  4.65E+5nMAssay Description:Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50527803(CHEMBL4557180)
Affinity DataKd:  3.80E+5nMAssay Description:Competitive binding affinity to recombinant full length human His-tagged LDH-1 (1 to 322 residues) expressed in Escherichia coli assessed as protein-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50527805(CHEMBL4440124)
Affinity DataKd:  1.02E+6nMAssay Description:Binding affinity to full length human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) in sodium phosphate buffer at pH 7.6 b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50527812(CHEMBL4475220)
Affinity DataKd:  1.49E+6nMAssay Description:Binding affinity to full length human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) in sodium phosphate buffer at pH 7.6 b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50420178(GUANIDINE)
Affinity DataEC50:  9.78E+8nMAssay Description:Binding affinity full length human N-terminal His6-tagged LDH-H T2A mutant expressed in Escherichia coli Rosetta (DE3) assessed as tetrameric disrupt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50527813(CHEMBL4456560)
Affinity DataKd:  6.40E+4nMAssay Description:Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50527814(CHEMBL4471310)
Affinity DataKd: >1.00E+6nMAssay Description:Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50527815(CHEMBL4468125)
Affinity DataKd:  1.42E+5nMAssay Description:Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50527816(CHEMBL4452577)
Affinity DataKd: >1.00E+6nMAssay Description:Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50527817(CHEMBL4466441)
Affinity DataKd: >1.00E+6nMAssay Description:Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50420178(GUANIDINE)
Affinity DataEC50:  1.11E+9nMAssay Description:Binding affinity to full length human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) assessed as tetrameric disruption by n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50420178(GUANIDINE)
Affinity DataEC50:  2.33E+8nMAssay Description:Binding affinity full length human N-terminal His6-tagged LDH-H I8A mutant expressed in Escherichia coli Rosetta (DE3) assessed as tetrameric disrupt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50527818(CHEMBL4575384)
Affinity DataKd:  1.05E+6nMAssay Description:Binding affinity to full length human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) in sodium phosphate buffer at pH 7.6 b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50420178(GUANIDINE)
Affinity DataEC50:  9.91E+8nMAssay Description:Binding affinity full length human N-terminal His6-tagged LDH-H K4A mutant expressed in Escherichia coli Rosetta (DE3) assessed as tetrameric disrupt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50597915(CHEMBL5185237)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50597915(CHEMBL5185237)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50597916(CHEMBL5201115)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50597916(CHEMBL5201115)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50597908(CHEMBL5181496)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50597908(CHEMBL5181496)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM197160(GNE-140 (6))
Affinity DataIC50: 5nMAssay Description:LDHA, LDHB, LDHC, MDH1 and MDH2 enzymatic assays have been described in detail previously [Dragovich, P.S. et al, Bioorg. Med. Chem. Lett. 24:3764-37...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM197160(GNE-140 (6))
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant carboxy-terminal His-tagged LDHB by UV endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50547002(CHEMBL4753379 | US11247971, Cmpd ID 449 | US117521...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human LDHBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50250655(CHEMBL4059985 | US10961200, Compound 189 | US11247...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2019
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50597909(CHEMBL5196929)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50597909(CHEMBL5196929)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50597898(CHEMBL5172378)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50597898(CHEMBL5172378)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50597913(CHEMBL5194549)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50597913(CHEMBL5194549)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50597906(CHEMBL5183539)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50597896(CHEMBL5181996)
Affinity DataIC50: 15nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50597896(CHEMBL5181996)
Affinity DataIC50: 15nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50597905(CHEMBL5182266)
Affinity DataIC50: 17nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50597905(CHEMBL5182266)
Affinity DataIC50: 17nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50250653(CHEMBL4090677 | US10961200, Compound 46 | US112479...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2019
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50250677(CHEMBL4100845 | US10961200, Compound 52 | US112479...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2019
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50597914(CHEMBL5188480)
Affinity DataIC50: 25nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50597914(CHEMBL5188480)
Affinity DataIC50: 25nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
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