Compile Data Set for Download or QSAR
Report error Found 107 of affinity data for UniProtKB/TrEMBL: P06795
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50109783(3-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-y...)
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against P-glycoprotein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50375811(XR-9544 | CHEMBL444075)
Affinity DataIC50: 50nMAssay Description:Inhibition of mouse Pgp in EMT6/AR1.0 cells after 1 hr by daunorubicin accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50075373(CHEMBL348475 | 1N-{4-[2-(6,7-dimethoxy-1,2,3,4-tet...)
Affinity DataIC50: 64nMAssay Description:Inhibition of mouse Pgp in EMT6/AR1.0 cells after 1 hr by daunorubicin accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50109790(5-Chloro-3-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoqui...)
Affinity DataIC50: 160nMAssay Description:Inhibitory activity against P-glycoprotein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50375812(XR-9504 | CHEMBL258896)
Affinity DataIC50: 260nMAssay Description:Inhibition of mouse Pgp in EMT6/AR1.0 cells after 1 hr by daunorubicin accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50375810(XR-9456 | CHEMBL346292)
Affinity DataIC50: 300nMAssay Description:Inhibition of mouse Pgp in EMT6/AR1.0 cells after 1 hr by daunorubicin accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50375813(XR-9577 | CHEMBL428402)
Affinity DataIC50: 320nMAssay Description:Inhibition of mouse Pgp in EMT6/AR1.0 cells after 1 hr by daunorubicin accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50109789(2-(4-Dimethylamino-phenyl)-3-[2-(4-pyrimidin-2-yl-...)
Affinity DataIC50: 390nMAssay Description:Inhibitory activity against P-glycoprotein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50109793(3-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-y...)
Affinity DataIC50: 600nMAssay Description:Inhibitory activity against P-glycoprotein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50109788(3-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-y...)
Affinity DataIC50: 630nMAssay Description:Inhibitory activity against P-glycoprotein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataIC50: 700nMAssay Description:Inhibition of P-glycoprotein, mouse L-mdr1b expressed in LLC-PK1 epithelial cells using calcein-AM polarisation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50127138(Oriconazole | Sporanox (TN) | 2-(butan-2-yl)-4-{4-...)
Affinity DataIC50: 700nMAssay Description:Inhibition of P-glycoprotein, mouse L-mdr1b expressed in LLC-PK1 epithelial cells using calcein-AM polarisation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50109786(3-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-y...)
Affinity DataIC50: 800nMAssay Description:Inhibitory activity against P-glycoprotein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50109809(3-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-y...)
Affinity DataIC50: 850nMAssay Description:Inhibitory activity against P-glycoprotein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50109800(3-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-y...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against P-glycoprotein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50109787(2-Biphenyl-4-yl-3-[2-(6,7-dimethoxy-3,4-dihydro-1H...)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibitory activity against P-glycoprotein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50109797(8-Chloro-3-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoqui...)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibitory activity against P-glycoprotein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50109796(3-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-y...)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibitory activity against P-glycoprotein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50109806(3-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-y...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against P-glycoprotein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50109810(2-(4-Diethylamino-phenyl)-3-[2-(6,7-dimethoxy-3,4-...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory activity against P-glycoprotein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50140804(4-{4-[2-(3,4-Difluoro-phenyl)-ethyl]-piperazin-1-y...)
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibitory activity against mouse transporter Pgp (P-glycoprotein) expressed in EMT6/AR1.0 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50109805(7-Chloro-3-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoqui...)
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibitory activity against P-glycoprotein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50109785(3-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-y...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory activity against P-glycoprotein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM24226(cid_2247 | [3H]-ASTEMIZOLE | Hismanal | ASTEMIZOLE...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of P-glycoprotein, mouse L-mdr1b expressed in LLC-PK1 epithelial cells using calcein-AM polarisation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50109782(6-Chloro-3-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoqui...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory activity against P-glycoprotein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50109794(3-(2-{[2-(3,4-Dimethoxy-phenyl)-ethyl]-methyl-amin...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory activity against P-glycoprotein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50109798(6-Amino-3-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquin...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against P-glycoprotein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50017376(1-(4-tert-butylphenyl)-4-(4-(hydroxydiphenylmethyl...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of P-glycoprotein, mouse L-mdr1b expressed in LLC-PK1 epithelial cells using calcein-AM polarisation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM31772(Brentan | 1-[2-(2,4-dichlorobenzyl)oxy-2-(2,4-dich...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of P-glycoprotein, mouse L-mdr1b expressed in LLC-PK1 epithelial cells using calcein-AM polarisation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50109804(3-[2-(4-Benzyl-piperazin-1-yl)-ethyl]-2-(4-dimethy...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibitory activity against P-glycoprotein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50140825(4-{4-[2-(3,4-Difluoro-phenyl)-ethyl]-piperazin-1-y...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibitory activity against mouse transporter Pgp (P-glycoprotein) expressed in EMT6/AR1.0 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataKi:  3.50E+3nMAssay Description:TP_TRANSPORTER: increase in Calcein-AM intracellular accumulation in mdr1b-expressing LLC-PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM31774(cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of P-glycoprotein, mouse L-mdr1b expressed in LLC-PK1 epithelial cells using calcein-AM polarisation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50140820(4-{4-[2-(3,4-Difluoro-phenyl)-ethyl]-piperazin-1-y...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibitory activity against mouse transporter Pgp (P-glycoprotein) expressed in EMT6/AR1.0 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50140812(10-(5-Methyl-[1,2,4]oxadiazol-3-yl)-4-(4-phenethyl...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibitory activity against mouse transporter Pgp (P-glycoprotein) expressed in EMT6/AR1.0 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50109802(2-Benzo[1,3]dioxol-5-yl-3-[2-(6,7-dimethoxy-3,4-di...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibitory activity against P-glycoprotein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50109784(2-(4-Dimethylamino-phenyl)-3-{2-[4-(3,4,5-trimetho...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibitory activity against P-glycoprotein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50140798(4-{4-[2-(3,4-Difluoro-phenyl)-ethyl]-piperazin-1-y...)
Affinity DataIC50: 4.79E+3nMAssay Description:Inhibitory activity against mouse transporter Pgp (P-glycoprotein) expressed in EMT6/AR1.0 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50140803(4-{4-[2-(3,4-Difluoro-phenyl)-ethyl]-piperazin-1-y...)
Affinity DataIC50: 4.95E+3nMAssay Description:Inhibitory activity against mouse transporter Pgp (P-glycoprotein) expressed in EMT6/AR1.0 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50109808(3-[2-(3,4-Dihydro-1H-isoquinolin-2-yl)-ethyl]-2-(4...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity against P-glycoprotein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50109811((S)-1-[2-Oxo-2-(3,4,5-trimethoxy-phenyl)-acetyl]-p...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity against P-glycoprotein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50140818(4-(4-Phenethyl-piperazin-1-yl)-2-phenyl-6,7,8,9-te...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity against mouse transporter Pgp (P-glycoprotein) expressed in EMT6/AR1.0 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50140827(N-(10-Cyano-6,7,8,9-tetrahydro-pyrimido[4,5-b]indo...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibitory activity against mouse transporter Pgp (P-glycoprotein) expressed in EMT6/AR1.0 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50140821(4-{4-[2-(1H-Indol-3-yl)-ethyl]-piperazin-1-yl}-6,7...)
Affinity DataIC50: 5.82E+3nMAssay Description:Inhibitory activity against mouse transporter Pgp (P-glycoprotein) expressed in EMT6/AR1.0 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50140816(10-(4,5-Dimethyl-thiazol-2-yl)-4-(4-phenethyl-pipe...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory activity against mouse transporter Pgp (P-glycoprotein) expressed in EMT6/AR1.0 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)
Affinity DataKi:  6.39E+3nMAssay Description:TP_TRANSPORTER: increase in Calcein-AM intracellular accumulation in mdr1b-expressing LLC-PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM151585(US8987315, Ketoconazole | US9180183, Ketoconazole ...)
Affinity DataKi:  6.93E+3nMAssay Description:TP_TRANSPORTER: increase in Calcein-AM intracellular accumulation in mdr1b-expressing LLC-PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50109801(7-Amino-3-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquin...)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibitory activity against P-glycoprotein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50012278(VINBLASTINE SULFATE | (2ALPHA,2''BETA,3BETA,4ALPHA...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of P-glycoprotein, mouse L-mdr1b expressed in LLC-PK1 epithelial cells using calcein-AM polarisation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Mouse)
Xenova

Curated by ChEMBL
LigandPNGBDBM50109795(3-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-y...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibitory activity against P-glycoprotein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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