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Report error Found 337 for UniProtKB: P06734
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132432({3-[1-(5-Methoxy-1-methyl-1H-indol-3-yl)-meth-(Z)-...)
Affinity DataEC50:  1.94E+3nMAssay Description:Effect on IgE/Fcepsilon RI triggered rat basophil cell (RBL-2H3) degranulation assessed by measuring the amount of 5-HT releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132433(3-[1-(5-Methoxy-1-methyl-1H-indol-3-yl)-meth-(Z)-y...)
Affinity DataEC50:  110nMAssay Description:Effect on IgE/Fcepsilon RI triggered rat basophil cell (RBL-2H3) degranulation assessed by measuring the amount of 5-HT releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132435(3-[1-(5-Methoxy-1-methyl-1H-indol-3-yl)-meth-(Z)-y...)
Affinity DataEC50:  3.50E+3nMAssay Description:Effect on IgE/Fcepsilon RI triggered rat basophil cell (RBL-2H3) degranulation assessed by measuring the amount of 5-HT releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132437(3-((1-(3-hydroxypropyl)-5-methoxy-1H-indol-3-yl)me...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effect on IgE/Fcepsilon RI triggered rat basophil cell (RBL-2H3) degranulation assessed by measuring the amount of 5-HT releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132441(3-(3-((5-methoxy-1-methyl-1H-indol-3-yl)methylene)...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effect on IgE/Fcepsilon RI triggered rat basophil cell (RBL-2H3) degranulation assessed by measuring the amount of 5-HT releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132438(2-Oxo-3-[1-[1-(4-oxo-4-piperidin-1-yl-butyl)-1H-in...)
Affinity DataEC50: >3.00E+4nMAssay Description:Effect on IgE/Fcepsilon RI triggered rat basophil cell (RBL-2H3) degranulation assessed by measuring the amount of 5-HT releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132445(3-[1-(5-Methoxy-1H-indol-3-yl)-meth-(Z)-ylidene]-2...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effect on IgE/Fcepsilon RI triggered rat basophil cell (RBL-2H3) degranulation assessed by measuring the amount of 5-HT releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132447(5-[5-Methoxy-3-(2-oxo-5-sulfamoyl-1,2-dihydro-indo...)
Affinity DataEC50:  2.07E+4nMAssay Description:Effect on IgE/Fcepsilon RI triggered rat basophil cell (RBL-2H3) degranulation assessed by measuring the amount of 5-HT releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132436(3-((1-methyl-1H-indol-3-yl)methylene)-2-oxoindolin...)
Affinity DataEC50:  313nMAssay Description:Effect on IgE/Fcepsilon RI triggered rat basophil cell (RBL-2H3) degranulation assessed by measuring the amount of 5-HT releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132449(3-((1-(4-morpholino-4-oxobutyl)-1H-indol-3-yl)meth...)
Affinity DataEC50:  5.60E+3nMAssay Description:Effect on IgE/Fcepsilon RI triggered rat basophil cell (RBL-2H3) degranulation assessed by measuring the amount of 5-HT releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132448(2-[3-(5-Methoxy-1-methyl-1H-indol-3-ylmethylene)-2...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effect on IgE/Fcepsilon RI triggered rat basophil cell (RBL-2H3) degranulation assessed by measuring the amount of 5-HT releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132450(3-[1-(5-Methoxy-1-methyl-1H-indol-3-yl)-meth-(Z)-y...)
Affinity DataEC50:  1.40E+3nMAssay Description:Effect on IgE/Fcepsilon RI triggered rat basophil cell (RBL-2H3) degranulation assessed by measuring the amount of 5-HT releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132443(4-{5-Methoxy-3-[2-oxo-5-sulfamoyl-1,2-dihydro-indo...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effect on IgE/Fcepsilon RI triggered rat basophil cell (RBL-2H3) degranulation assessed by measuring the amount of 5-HT releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132451(3-[1-(5-Methoxy-1-methyl-1H-indol-3-yl)-meth-(Z)-y...)
Affinity DataEC50:  100nMAssay Description:Effect on IgE/Fcepsilon RI triggered rat basophil cell (RBL-2H3) degranulation assessed by measuring the amount of 5-HT releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132444(5-{5-Methoxy-3-[2-oxo-5-sulfamoyl-1,2-dihydro-indo...)
Affinity DataEC50:  6.96E+3nMAssay Description:Effect on IgE/Fcepsilon RI triggered rat basophil cell (RBL-2H3) degranulation assessed by measuring the amount of 5-HT releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132454(6-{5-Methoxy-3-[2-oxo-5-sulfamoyl-1,2-dihydro-indo...)
Affinity DataEC50:  6.30E+3nMAssay Description:Effect on IgE/Fcepsilon RI triggered rat basophil cell (RBL-2H3) degranulation assessed by measuring the amount of 5-HT releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132455(3-[1-(5-Methoxy-1-methyl-1H-indol-3-yl)-meth-(Z)-y...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effect on IgE/Fcepsilon RI triggered rat basophil cell (RBL-2H3) degranulation assessed by measuring the amount of 5-HT releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
LigandPNGBDBM703707(3-[[4-[3-fluoro-5- isobutyl-2-(2H- tetrazol-5-yl)p...)
Affinity DataIC50: 0.893nMAssay Description:All synthesized ligands were evaluated in a radioligand assay by displacing 125I-[Sar1, Ile8]-Angiotensin II (Perkin Elmer, NEX248050UC) from human A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
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LigandPNGBDBM703697(3-[[(2S)-4-[3-fluoro- 5-isobutyl-2-(2H- tetrazol-5...)
Affinity DataIC50: 2.35nMAssay Description:All synthesized ligands were evaluated in a radioligand assay by displacing 125I-[Sar1, Ile8]-Angiotensin II (Perkin Elmer, NEX248050UC) from human A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

LigandPNGBDBM703740((2S)-4-[3-fluoro-5- isobutyl-2-(2H- tetrazol-5-yl)...)
Affinity DataIC50: 2.79nMAssay Description:All synthesized ligands were evaluated in a radioligand assay by displacing 125I-[Sar1, Ile8]-Angiotensin II (Perkin Elmer, NEX248050UC) from human A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

LigandPNGBDBM703703(3-[[4-[3-fluoro-5- isobutyl-2-(2H- tetrazol-5-yl)p...)
Affinity DataIC50: 3.95nMAssay Description:All synthesized ligands were evaluated in a radioligand assay by displacing 125I-[Sar1, Ile8]-Angiotensin II (Perkin Elmer, NEX248050UC) from human A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

LigandPNGBDBM703746(2-[[(2S)-4-[3-fluoro- 5-isobutyl-2-(2H- tetrazol-5...)
Affinity DataIC50: 6nMAssay Description:All synthesized ligands were evaluated in a radioligand assay by displacing 125I-[Sar1, Ile8]-Angiotensin II (Perkin Elmer, NEX248050UC) from human A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

LigandPNGBDBM703710(3-[[(2S,6S)-4-[3- fluoro-5-isobutyl-2- (2H-tetrazo...)
Affinity DataIC50: 7.26nMAssay Description:All synthesized ligands were evaluated in a radioligand assay by displacing 125I-[Sar1, Ile8]-Angiotensin II (Perkin Elmer, NEX248050UC) from human A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

LigandPNGBDBM703752((2S)-4-[3-fluoro-5- isobutyl-2-(2H- tetrazol-5-yl)...)
Affinity DataIC50: 7.98nMAssay Description:All synthesized ligands were evaluated in a radioligand assay by displacing 125I-[Sar1, Ile8]-Angiotensin II (Perkin Elmer, NEX248050UC) from human A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

LigandPNGBDBM703706(3-[[4-[3-fluoro-5- isobutyl-2-(2H- tetrazol-5-yl)p...)
Affinity DataIC50: 8.33nMAssay Description:All synthesized ligands were evaluated in a radioligand assay by displacing 125I-[Sar1, Ile8]-Angiotensin II (Perkin Elmer, NEX248050UC) from human A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

LigandPNGBDBM703750((2S)-4-[3-fluoro-5- isobutyl-2-(2H- tetrazol-5-yl)...)
Affinity DataIC50: 8.75nMAssay Description:All synthesized ligands were evaluated in a radioligand assay by displacing 125I-[Sar1, Ile8]-Angiotensin II (Perkin Elmer, NEX248050UC) from human A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

LigandPNGBDBM703745(2-[[4-[3-fluoro-5- isobutyl-2-(2H- tetrazol-5-yl)p...)
Affinity DataIC50: 9.47nMAssay Description:All synthesized ligands were evaluated in a radioligand assay by displacing 125I-[Sar1, Ile8]-Angiotensin II (Perkin Elmer, NEX248050UC) from human A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069616((2R,3S)-N*1*-Hydroxy-2-{2-[(E)-hydroxyimino]-2-phe...)
Affinity DataIC50: 12nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 100-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM703659(2-[[4-[3-ethyl-5- isobutyl-2-(2H- tetrazol-5-yl)ph...)
Affinity DataIC50: 12.1nMAssay Description:All synthesized ligands were evaluated in a radioligand assay by displacing 125I-[Sar1, Ile8]-Angiotensin II (Perkin Elmer, NEX248050UC) from human A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069604([(2S,3R)-3-((S)-1-Carbamoyl-2-phenyl-ethylcarbamoy...)
Affinity DataIC50: 13nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 100-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM703711(3-[[4-[3-fluoro-5- isobutyl-2-(2H- tetrazol-5-yl)p...)
Affinity DataIC50: 13.9nMAssay Description:All synthesized ligands were evaluated in a radioligand assay by displacing 125I-[Sar1, Ile8]-Angiotensin II (Perkin Elmer, NEX248050UC) from human A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

LigandPNGBDBM703704(3-[[3-ethyl-4-[3- fluoro-5-isobutyl-2- (2H-tetrazo...)
Affinity DataIC50: 14.8nMAssay Description:All synthesized ligands were evaluated in a radioligand assay by displacing 125I-[Sar1, Ile8]-Angiotensin II (Perkin Elmer, NEX248050UC) from human A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

LigandPNGBDBM703751((2S)-4-[3-fluoro-5- isobutyl-2-(2H- tetrazol-5-yl)...)
Affinity DataIC50: 14.9nMAssay Description:All synthesized ligands were evaluated in a radioligand assay by displacing 125I-[Sar1, Ile8]-Angiotensin II (Perkin Elmer, NEX248050UC) from human A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

LigandPNGBDBM703694(5-isobutyl-N-meth- yl-3-[4-(pyridazin- 3-ylmethyl)...)
Affinity DataIC50: 15.8nMAssay Description:All synthesized ligands were evaluated in a radioligand assay by displacing 125I-[Sar1, Ile8]-Angiotensin II (Perkin Elmer, NEX248050UC) from human A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069601((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)
Affinity DataIC50: 16nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 100-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM703660(2-[[4-[3-cycloprop- yl-5-isobutyl-2- (2H-tetrazol-...)
Affinity DataIC50: 16nMAssay Description:All synthesized ligands were evaluated in a radioligand assay by displacing 125I-[Sar1, Ile8]-Angiotensin II (Perkin Elmer, NEX248050UC) from human A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

LigandPNGBDBM703696(3-[[4-[3-fluoro-5- isobutyl-2-(2H- tetrazol-5-yl)p...)
Affinity DataIC50: 16nMAssay Description:All synthesized ligands were evaluated in a radioligand assay by displacing 125I-[Sar1, Ile8]-Angiotensin II (Perkin Elmer, NEX248050UC) from human A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

LigandPNGBDBM703691(3-[4-[3-ethyl-5- isobutyl-2-(2H- tetrazol-5-yl)phe...)
Affinity DataIC50: 17.7nMAssay Description:All synthesized ligands were evaluated in a radioligand assay by displacing 125I-[Sar1, Ile8]-Angiotensin II (Perkin Elmer, NEX248050UC) from human A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

LigandPNGBDBM703709(3-[[(2S,6R)-4-[3- fluoro-5-isobutyl-2- (2H-tetrazo...)
Affinity DataIC50: 18.3nMAssay Description:All synthesized ligands were evaluated in a radioligand assay by displacing 125I-[Sar1, Ile8]-Angiotensin II (Perkin Elmer, NEX248050UC) from human A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

LigandPNGBDBM703705(3-[[4-[3-fluoro-5- isobutyl-2-(2H- tetrazol-5-yl)p...)
Affinity DataIC50: 18.6nMAssay Description:All synthesized ligands were evaluated in a radioligand assay by displacing 125I-[Sar1, Ile8]-Angiotensin II (Perkin Elmer, NEX248050UC) from human A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069620((2R,3S)-N*1*-((S)-1-Carbamoyl-2-phenyl-ethyl)-N*4*...)
Affinity DataIC50: 20nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 100-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082225((2R,3S)-N*4*-((S)-1-Carbamoyl-2,2-dimethyl-propyl)...)
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against IgE receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082218((2R,3S)-2-Benzo[b]thiophen-2-ylmethyl-N*1*-((S)-1-...)
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against IgE receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082226((2R,3S)-N*4*-((S)-1-Carbamoyl-2,2-dimethyl-propyl)...)
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against IgE receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM703658(2-[4-[5-isobutyl-3- methyl-2-(2H- tetrazol-5-yl)ph...)
Affinity DataIC50: 22nMAssay Description:All synthesized ligands were evaluated in a radioligand assay by displacing 125I-[Sar1, Ile8]-Angiotensin II (Perkin Elmer, NEX248050UC) from human A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

LigandPNGBDBM703692(3-[[4-[3-cycloprop- yl-5-isobutyl-2-(2H- tetrazol-...)
Affinity DataIC50: 25.3nMAssay Description:All synthesized ligands were evaluated in a radioligand assay by displacing 125I-[Sar1, Ile8]-Angiotensin II (Perkin Elmer, NEX248050UC) from human A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

LigandPNGBDBM703699(3-[[(2S)-4-[2-fluoro- 3-isobutyl-6-(2H- tetrazol-5...)
Affinity DataIC50: 28.7nMAssay Description:All synthesized ligands were evaluated in a radioligand assay by displacing 125I-[Sar1, Ile8]-Angiotensin II (Perkin Elmer, NEX248050UC) from human A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069597((2R,3S)-N*1*-((S)-1-Carbamoyl-2-phenyl-ethyl)-N*4*...)
Affinity DataIC50: 30nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 100-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069606((2R,3S)-2-Benzylsulfanylmethyl-N*1*-hydroxy-3-isob...)
Affinity DataIC50: 30nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 30-1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM703690(3-[[4-[5-isobutyl-3- methyl-2-(2H- tetrazol-5-yl)p...)
Affinity DataIC50: 32.6nMAssay Description:All synthesized ligands were evaluated in a radioligand assay by displacing 125I-[Sar1, Ile8]-Angiotensin II (Perkin Elmer, NEX248050UC) from human A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

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