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Report error Found 19 of affinity data for UniProtKB/TrEMBL: P06151
TargetL-lactate dehydrogenase A chain(Mouse)
Chinook Therapeutics

Curated by ChEMBL
LigandPNGBDBM50250656(CHEMBL4081890 | US11247971, Cmpd ID 276)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of recombinant mouse LDHA expressed in BL21 gold (DE3) using sodium pyruvate as substrate preincubated for 10 mins followed by sodium pyru...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Mouse)
Chinook Therapeutics

Curated by ChEMBL
LigandPNGBDBM50572933(CHEMBL4861379)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant mouse LDHA expressed in BL21 gold (DE3) using sodium pyruvate as substrate preincubated for 10 mins followed by sodium pyru...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Mouse)
Chinook Therapeutics

Curated by ChEMBL
LigandPNGBDBM50572931(CHEMBL4855986)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant mouse LDHA expressed in BL21 gold (DE3) using sodium pyruvate as substrate preincubated for 10 mins followed by sodium pyru...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Mouse)
Chinook Therapeutics

Curated by ChEMBL
LigandPNGBDBM50572930(CHEMBL4873879)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant mouse LDHA expressed in BL21 gold (DE3) using sodium pyruvate as substrate preincubated for 10 mins followed by sodium pyru...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Mouse)
Chinook Therapeutics

Curated by ChEMBL
LigandPNGBDBM50572934(CHEMBL4847068)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant mouse LDHA expressed in BL21 gold (DE3) using sodium pyruvate as substrate preincubated for 10 mins followed by sodium pyru...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Mouse)
Chinook Therapeutics

Curated by ChEMBL
LigandPNGBDBM50572932(CHEMBL4850573)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant mouse LDHA expressed in BL21 gold (DE3) using sodium pyruvate as substrate preincubated for 10 mins followed by sodium pyru...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Mouse)
Chinook Therapeutics

Curated by ChEMBL
LigandPNGBDBM50572929(CHEMBL4864519)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of recombinant mouse LDHA expressed in BL21 gold (DE3) using sodium pyruvate as substrate preincubated for 10 mins followed by sodium pyru...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Mouse)
Chinook Therapeutics

Curated by ChEMBL
LigandPNGBDBM50572929(CHEMBL4864519)
Affinity DataIC50: 136nMAssay Description:Inhibition of LDHA in wild type CD1 mouse primary hepatocyte assessed as inhibition of lactate production using pyruvate as substrate measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Mouse)
Chinook Therapeutics

Curated by ChEMBL
LigandPNGBDBM50572931(CHEMBL4855986)
Affinity DataIC50: 143nMAssay Description:Inhibition of LDHA in wild type CD1 mouse primary hepatocyte assessed as inhibition of lactate production using pyruvate as substrate measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Mouse)
Chinook Therapeutics

Curated by ChEMBL
LigandPNGBDBM50572934(CHEMBL4847068)
Affinity DataIC50: 170nMAssay Description:Inhibition of LDHA in wild type CD1 mouse primary hepatocyte assessed as inhibition of lactate production using pyruvate as substrate measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Mouse)
Chinook Therapeutics

Curated by ChEMBL
LigandPNGBDBM50572932(CHEMBL4850573)
Affinity DataIC50: 198nMAssay Description:Inhibition of LDHA in wild type CD1 mouse primary hepatocyte assessed as inhibition of lactate production using pyruvate as substrate measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Mouse)
Chinook Therapeutics

Curated by ChEMBL
LigandPNGBDBM50572933(CHEMBL4861379)
Affinity DataIC50: 230nMAssay Description:Inhibition of LDHA in wild type CD1 mouse primary hepatocyte assessed as inhibition of lactate production using pyruvate as substrate measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Mouse)
Chinook Therapeutics

Curated by ChEMBL
LigandPNGBDBM50572930(CHEMBL4873879)
Affinity DataIC50: 732nMAssay Description:Inhibition of LDHA in wild type CD1 mouse primary hepatocyte assessed as inhibition of lactate production using pyruvate as substrate measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Mouse)
Chinook Therapeutics

Curated by ChEMBL
LigandPNGBDBM23222(carbamoylformic acid | Oxalamic acid | Oxamidic Ac...)
Affinity DataIC50: 8.00E+4nMpH: 7.4Assay Description:Lactate dehydrogenase activity was determined by recording the absorbance change at 340 nm produced by the oxidation of NADH. Assays were performed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetL-lactate dehydrogenase A chain(Mouse)
Chinook Therapeutics

Curated by ChEMBL
LigandPNGBDBM234443(N-Ethyl oxamate)
Affinity DataIC50: 1.40E+5nMpH: 7.4Assay Description:Lactate dehydrogenase activity was determined by recording the absorbance change at 340 nm produced by the oxidation of NADH. Assays were performed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Mouse)
Chinook Therapeutics

Curated by ChEMBL
LigandPNGBDBM234447(N-sec-Butyl oxamate)
Affinity DataIC50: 1.25E+7nMpH: 7.4Assay Description:Lactate dehydrogenase activity was determined by recording the absorbance change at 340 nm produced by the oxidation of NADH. Assays were performed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Mouse)
Chinook Therapeutics

Curated by ChEMBL
LigandPNGBDBM234446(N-Isobutyl oxamate)
Affinity DataIC50: 6.00E+6nMpH: 7.4Assay Description:Lactate dehydrogenase activity was determined by recording the absorbance change at 340 nm produced by the oxidation of NADH. Assays were performed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Mouse)
Chinook Therapeutics

Curated by ChEMBL
LigandPNGBDBM234445(N-Butyl oxamate)
Affinity DataIC50: 9.10E+6nMpH: 7.4Assay Description:Lactate dehydrogenase activity was determined by recording the absorbance change at 340 nm produced by the oxidation of NADH. Assays were performed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Mouse)
Chinook Therapeutics

Curated by ChEMBL
LigandPNGBDBM234444(N-Propyl oxamate)
Affinity DataIC50: 1.75E+6nMpH: 7.4Assay Description:Lactate dehydrogenase activity was determined by recording the absorbance change at 340 nm produced by the oxidation of NADH. Assays were performed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed