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Report error Found 6 of affinity data for UniProtKB/TrEMBL: P05050
TargetAlpha-ketoglutarate-dependent dioxygenase AlkB(Escherichia coli (strain K12))
University College London

Curated by ChEMBL
LigandPNGBDBM50396018(CHEMBL1230640)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of Escherichia coli AlkB DNA repair activity using 1-methyladenine with GC-1meA-AGGTCCCGTAGTGCG sequence as substrate by FDH coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAlpha-ketoglutarate-dependent dioxygenase AlkB(Escherichia coli (strain K12))
University College London

Curated by ChEMBL
LigandPNGBDBM32021(RHEIN | cid_10168 | SMR000058210 | MLS000069639 | ...)
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of Escherichia coli AlkB by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAlpha-ketoglutarate-dependent dioxygenase AlkB(Escherichia coli (strain K12))
University College London

Curated by ChEMBL
LigandPNGBDBM50417864(CHEMBL5286796)
Affinity DataIC50: 1.94E+4nMAssay Description:Inhibition of Escherichia coli AlkB-mediated demethylation using 40-mer single N3-meC containing ssDNA as substrate preincubated for 1 hr followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase AlkB(Escherichia coli (strain K12))
University College London

Curated by ChEMBL
LigandPNGBDBM50596053(CHEMBL5173876)
Affinity DataIC50: 3.35E+4nMAssay Description:Inhibition of Escherichia coli AlkB using 15-mer m1A-ssDNA as substrate incubated for 10 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase AlkB(Escherichia coli (strain K12))
University College London

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | Oxalylglycine | [(carboxymethyl)carb...)
Affinity DataIC50: 1.08E+5nMAssay Description:Inhibition of Escherichia coli AlkB using 15-mer m1A-ssDNA as substrate incubated for 10 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase AlkB(Escherichia coli (strain K12))
University College London

Curated by ChEMBL
LigandPNGBDBM50416550(CHEMBL5274121)
Affinity DataIC50: 1.69E+5nMAssay Description:Inhibition of Escherichia coli AlkB using 15-mer m1A-ssDNA as substrate incubated for 10 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed