Compile Data Set for Download or QSAR
Report error Found 77 of affinity data for UniProtKB/TrEMBL: P04409
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50057512((1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-4a,7b-dihydroxy-3-...)
Affinity DataKi:  0.200nMAssay Description:Ability to displace bound [20-3H]-PDBU from a recombinant single isozyme (PKCalpha) in the presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50133238(Hexadecanedioic acid ((S)-5-hydroxymethyl-2-isopro...)
Affinity DataKi:  1.80nMAssay Description:Tested for ability to displace [20e3] phorbol 12,13- dibutyrate binding from recombinant bovine Protein kinase C alpha in presence of [Ca2+]More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50133235(Docosanedioic acid ((S)-5-hydroxymethyl-2-isopropy...)
Affinity DataKi:  2.40nMAssay Description:Tested for ability to displace [20e3] phorbol 12,13- dibutyrate binding from recombinant bovine Protein kinase C alpha in presence of [Ca2+]More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50133236(Tetradecanedioic acid ((S)-5-hydroxymethyl-2-isopr...)
Affinity DataKi:  3.70nMAssay Description:Tested for ability to displace [20e3] phorbol 12,13- dibutyrate binding from recombinant bovine Protein kinase C alpha in presence of [Ca2+]More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50368315(PROSTRATIN)
Affinity DataKi:  4.80nMAssay Description:Ability to displace bound [20-3H]-PDBU from a recombinant single isozyme (PKCalpha) in the presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50133249(Dodecanedioic acid [(S)-5-hydroxymethyl-2-((S)-iso...)
Affinity DataKi:  5.60nMAssay Description:Tested for ability to displace [20e3] phorbol 12,13- dibutyrate binding from recombinant bovine Protein kinase C alpha in presence of [Ca2+]More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50100125(3-Isopropyl-4-methyl-pent-2-enoic acid 3-hydroxy-2...)
Affinity DataKi:  24.6nMAssay Description:Ability to displace bound [20-3H]-PDBU from a recombinant single isozyme (PKCalpha) in the presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50087241(3-Isopropyl-4-methyl-pentanoic acid 3-hydroxy-2-(3...)
Affinity DataKi:  28.6nMAssay Description:Ability to displace bound [20-3H]-PDBU from a recombinant single isozyme (PKCalpha) in the presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50100126(3-Isopropyl-4-methyl-pent-2-enoic acid 1-hydroxyme...)
Affinity DataKi:  31.1nMAssay Description:Ability to displace bound [20-3H]-PDBU from a recombinant single isozyme (PKCalpha) in the presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50015677(CHEMBL55267 | 1,2-dioctanoyl-sn-glycerol | 1,2-Dio...)
Affinity DataKi:  33nMAssay Description:Ability to displace bound [20-3H]-PDBU from a recombinant single isozyme (PKCalpha) in the presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50133243(Decanedioic acid ((S)-5-hydroxymethyl-2-isopropyl-...)
Affinity DataKi:  38nMAssay Description:Tested for ability to displace [20e3] phorbol 12,13- dibutyrate binding from recombinant bovine Protein kinase C alpha in presence of [Ca2+]More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50100129(3-Isopropyl-4-methyl-pentanoic acid 3-hydroxy-2-(3...)
Affinity DataKi:  39.9nMAssay Description:Ability to displace bound [20-3H]-PDBU from a recombinant single isozyme (PKCalpha) in the presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50100122(3-Isopropyl-4-methyl-pent-2-enoic acid 1-hydroxyme...)
Affinity DataKi:  44.5nMAssay Description:Ability to displace bound [20-3H]-PDBU from a recombinant single isozyme (PKCalpha) in the presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50100118(Octadec-9-enoic acid 2-acetoxy-3-hydroxy-propyl es...)
Affinity DataKi:  50.4nMAssay Description:Ability to displace bound [20-3H]-PDBU from a recombinant single isozyme (PKCalpha) in the presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50133240(Decanedioic acid ((2S,5S)-5-hydroxymethyl-2-isopro...)
Affinity DataKi:  57nMAssay Description:Tested for ability to displace [20e3] phorbol 12,13- dibutyrate binding from recombinant bovine Protein kinase C alpha in presence of [Ca2+]More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50100127(3-Isopropyl-4-methyl-pent-2-enoic acid 1-hydroxyme...)
Affinity DataKi:  68.3nMAssay Description:Ability to displace bound [20-3H]-PDBU from a recombinant single isozyme (PKCalpha) in the presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50100123(3-Isopropyl-4-methyl-pentanoic acid 3-hydroxy-2-(3...)
Affinity DataKi:  71nMAssay Description:Ability to displace bound [20-3H]-PDBU from a recombinant single isozyme (PKCalpha) in the presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50100119(3-Isopropyl-4-methyl-pent-2-enoic acid 3-hydroxy-2...)
Affinity DataKi:  73nMAssay Description:Ability to displace bound [20-3H]-PDBU from a recombinant single isozyme (PKCalpha) in the presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50100115(3-Isopropyl-4-methyl-pentanoic acid 1-hydroxymethy...)
Affinity DataKi:  74.9nMAssay Description:Ability to displace bound [20-3H]-PDBU from a recombinant single isozyme (PKCalpha) in the presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50087240((E)-Octadec-9-enoic acid (S)-1-hydroxymethyl-2-((E...)
Affinity DataKi:  87.2nMAssay Description:Ability to displace bound [20-3H]-PDBU from a recombinant single isozyme (PKCalpha) in the presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50100117(3-Isopropyl-4-methyl-pent-2-enoic acid 3-hydroxy-2...)
Affinity DataKi:  110nMAssay Description:Ability to displace bound [20-3H]-PDBU from a recombinant single isozyme (PKCalpha) in the presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50133251(Tetradecanedioic acid 4-(2-hydroxymethyl-4-isoprop...)
Affinity DataKi:  154nMAssay Description:Tested for ability to displace [20e3] phorbol 12,13- dibutyrate binding from recombinant bovine Protein kinase C alpha in presence of [Ca2+]More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50100120(3-Isopropyl-4-methyl-pentanoic acid 1-hydroxymethy...)
Affinity DataKi:  154nMAssay Description:Ability to displace bound [20-3H]-PDBU from a recombinant single isozyme (PKCalpha) in the presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50133248(Dodecanedioic acid 4-(2-hydroxymethyl-4-isopropyl-...)
Affinity DataKi:  169nMAssay Description:Tested for ability to displace [20e3] phorbol 12,13- dibutyrate binding from recombinant bovine Protein kinase C alpha in presence of [Ca2+]More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50133241(Octanedioic acid 4-(2-hydroxymethyl-4-isopropyl-5-...)
Affinity DataKi:  174nMAssay Description:Tested for ability to displace [20e3] phorbol 12,13- dibutyrate binding from recombinant bovine Protein kinase C alpha in presence of [Ca2+]More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50283474(Acetic acid (2S,3R)-2-hydroxymethyl-6-oxo-5-tetrad...)
Affinity DataKi:  200nMAssay Description:Displacement of [3H-20]-phorbol-12-13-dibutyrate from bovine brain protein kinase C alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50281846((2R,3R)-2-Hydroxymethyl-5-oxo-4-tridec-(E)-ylidene...)
Affinity DataKi:  200nMAssay Description:Displacement of [3H-20]-phorbol-12-13-dibutyrate from bovine brain protein kinase C alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50133247(Decanedioic acid 4-(2-hydroxymethyl-4-isopropyl-5-...)
Affinity DataKi:  208nMAssay Description:Tested for ability to displace [20e3] phorbol 12,13- dibutyrate binding from recombinant bovine Protein kinase C alpha in presence of [Ca2+]More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50122946(Hexanoic acid [(S)-5-hydroxymethyl-2-((S)-isopropy...)
Affinity DataKi:  225nMAssay Description:Tested for ability to displace [20e3] phorbol 12,13- dibutyrate binding from recombinant bovine Protein kinase C alpha in presence of [Ca2+]More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50133244(Hexadecanedioic acid 4-(2-hydroxymethyl-4-isopropy...)
Affinity DataKi:  254nMAssay Description:Tested for ability to displace [20e3] phorbol 12,13- dibutyrate binding from recombinant bovine Protein kinase C alpha in presence of [Ca2+]More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50133242(Hexanedioic acid 4-(2-hydroxymethyl-4-isopropyl-5-...)
Affinity DataKi:  278nMAssay Description:Tested for ability to displace [20e3] phorbol 12,13- dibutyrate binding from recombinant bovine Protein kinase C alpha in presence of [Ca2+]More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50133237(Nonanoic acid 4-((2S,4R)-2-hydroxymethyl-4-isoprop...)
Affinity DataKi:  296nMAssay Description:Tested for ability to displace [20e3] phorbol 12,13- dibutyrate binding from recombinant bovine Protein kinase C alpha in presence of [Ca2+]More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50133250(Docosanedioic acid 4-(2-hydroxymethyl-4-isopropyl-...)
Affinity DataKi:  296nMAssay Description:Tested for ability to displace [20e3] phorbol 12,13- dibutyrate binding from recombinant bovine Protein kinase C alpha in presence of [Ca2+]More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50281845((2R,3R)-2-Hydroxymethyl-5-oxo-4-tridec-(E)-ylidene...)
Affinity DataKi:  300nMAssay Description:Displacement of [3H-20]-phorbol-12-13-dibutyrate from bovine brain protein kinase C alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50133246(Hexanedioic acid [(S)-5-hydroxymethyl-2-((S)-isopr...)
Affinity DataKi:  320nMAssay Description:Tested for ability to displace [20e3] phorbol 12,13- dibutyrate binding from recombinant bovine Protein kinase C alpha in presence of [Ca2+]More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50100121(3-Isopropyl-4-methyl-pent-2-enoic acid 1-hydroxyme...)
Affinity DataKi:  330nMAssay Description:Ability to displace bound [20-3H]-PDBU from a recombinant single isozyme (PKCalpha) in the presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50133245(Octanedioic acid ((1S,6S)-5-hydroxymethyl-2-isopro...)
Affinity DataKi:  558nMAssay Description:Tested for ability to displace [20e3] phorbol 12,13- dibutyrate binding from recombinant bovine Protein kinase C alpha in presence of [Ca2+]More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM3014(3-({4-[(3-chlorophenyl)amino]-1H-pyrazolo[3,4-d]py...)
Affinity DataIC50: 560nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2005
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM3012(4-({4-[(3-chlorophenyl)amino]-1H-pyrazolo[3,4-d]py...)
Affinity DataIC50: 1.00E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2005
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM3016(3-N-(4-aminophenyl)-4-N-(3-chlorophenyl)-1H-pyrazo...)
Affinity DataIC50: 1.00E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2005
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50100116(3-Methyl-but-2-enoic acid 1-hydroxymethyl-2-(3-met...)
Affinity DataKi:  1.05E+3nMAssay Description:Ability to displace bound [20-3H]-PDBU from a recombinant single isozyme (PKCalpha) in the presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50283473(Acetic acid (2S,3R)-2-hydroxymethyl-6-oxo-5-tetrad...)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [3H-20]-phorbol-12-13-dibutyrate from bovine brain protein kinase C alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50100128(3-Methyl-butyric acid 1-hydroxymethyl-2-(3-methyl-...)
Affinity DataKi:  1.41E+3nMAssay Description:Ability to displace bound [20-3H]-PDBU from a recombinant single isozyme (PKCalpha) in the presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM3027(3-(3-Aminophenyl)-4-((3-chlorophenyl)amino)-1H-pyr...)
Affinity DataIC50: 1.50E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2005
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50100124(3-Methyl-but-2-enoic acid 3-hydroxy-2-(3-methyl-bu...)
Affinity DataKi:  1.80E+3nMAssay Description:Ability to displace bound [20-3H]-PDBU from a recombinant single isozyme (PKCalpha) in the presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM3025(4-{4-[(3-chlorophenyl)amino]-1H-pyrazolo[3,4-d]pyr...)
Affinity DataIC50: 1.85E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2005
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50283471(Acetic acid (2S,3R)-2-hydroxymethyl-6-oxo-5-tetrad...)
Affinity DataKi:  1.90E+3nMAssay Description:Displacement of [3H-20]-phorbol-12-13-dibutyrate from bovine brain protein kinase C alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50100113(3-Methyl-but-2-enoic acid 1-hydroxymethyl-2-(3-met...)
Affinity DataKi:  2.40E+3nMAssay Description:Ability to displace bound [20-3H]-PDBU from a recombinant single isozyme (PKCalpha) in the presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM3017(3-((4-(Dimethylamino)phenyl)amino)-4-((3-chlorophe...)
Affinity DataIC50: 2.90E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2005
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM3029(3-(4-Aminophenyl)-4-((3-chlorophenyl)amino)-1H-pyr...)
Affinity DataIC50: 3.60E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2005
Entry Details Article
PubMed
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