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TargetTubulin alpha-1A/beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50030765(NPI-2358 | Plinabulin)
Affinity DataKd:  1.00E+3nMAssay Description:Binding affinity to porcine tubulin incubated for 1 hr by spectrofluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50030766(CHEMBL3342339)
Affinity DataKd:  1.30E+3nMAssay Description:Binding affinity to porcine tubulin incubated for 1 hr by spectrofluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50030765(NPI-2358 | Plinabulin)
Affinity DataKd:  1.06E+3nMAssay Description:Binding affinity to porcine tubulin after 1 hr by spectrofluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50483308(CHEMBL1643852)
Affinity DataKd:  1.79E+4nMAssay Description:Binding affinity to porcine tubulin after 1 hr by spectrofluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50014846(7alphaH-colchicine | (S)-N-(5,6,7,9-tetrahydro-1,2...)
Affinity DataKd:  3.70E+3nMAssay Description:Binding affinity to porcine tubulin after 1 hr by spectrofluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50482142(KPU-244-B3 | CHEMBL1096312)
Affinity DataKd:  2.52E+4nMAssay Description:Binding affinity to pig tubulin after 1 hr by fluorescence quenching analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50030765(NPI-2358 | Plinabulin)
Affinity DataKd:  1.06E+3nMAssay Description:Binding affinity to pig tubulin after 1 hr by fluorescence quenching analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50482143(KPU-244-B2 | CHEMBL1077255)
Affinity DataKd:  9.74E+3nMAssay Description:Binding affinity to pig tubulin after 1 hr by fluorescence quenching analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50030765(NPI-2358 | Plinabulin)
Affinity DataKd:  1.06E+3nMAssay Description:Binding affinity to porcine tubulin after 1 hr by spectrofluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50485035(CHEMBL2024561)
Affinity DataKd:  620nMAssay Description:Binding affinity to porcine tubulin after 1 hr by spectrofluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50485036(CHEMBL2024544)
Affinity DataKd:  200nMAssay Description:Binding affinity to porcine tubulin after 1 hr by spectrofluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50001839(CHEMBL428647 | taxol | PACLITAXEL)
Affinity DataEC50:  520nMAssay Description:Induction of porcine brain tubulin polymerization after 20 mins by Bradford assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50485690(CHEMBL2152244)
Affinity DataEC50:  680nMAssay Description:Induction of porcine brain tubulin polymerization after 20 mins by Bradford assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50520178(CHEMBL4468642)
Affinity DataKd:  2.66E+3nMAssay Description:Binding affinity to porcine brain tubulin polymerization by surface plasmon analysis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50014846(7alphaH-colchicine | (S)-N-(5,6,7,9-tetrahydro-1,2...)
Affinity DataKd:  1.13E+4nMAssay Description:Binding affinity to porcine brain tubulin polymerization by surface plasmon analysis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50609720(CHEMBL5285469)
Affinity DataKd:  1.70E+3nMAssay Description:Binding affinity to porcine brain tubulin assessed as changes in the fluorescence incubated for 10 mins tryptophan-based binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50609721(CHEMBL5270408)
Affinity DataKd:  4.49E+3nMAssay Description:Binding affinity to porcine brain tubulin assessed as changes in the fluorescence incubated for 10 mins tryptophan-based binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50005480(combretastin A4 | CHEMBL67 | 2-Methoxy-5-[2-(3,4,5...)
Affinity DataKd:  3.51E+3nMAssay Description:Binding affinity to porcine brain tubulin assessed as changes in the fluorescence incubated for 10 mins tryptophan-based binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50500878(CHEMBL3799906)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of porcine brain tubulin polymerization measured every 1 min for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50500880(CHEMBL3799435)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of porcine brain tubulin polymerization measured every 1 min for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50500879(CHEMBL3800118)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of porcine brain tubulin polymerization measured every 1 min for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50014846(7alphaH-colchicine | (S)-N-(5,6,7,9-tetrahydro-1,2...)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of porcine brain tubulin polymerization measured every 1 min for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50014846(7alphaH-colchicine | (S)-N-(5,6,7,9-tetrahydro-1,2...)
Affinity DataIC50: 10nMAssay Description:Inhibition of porcine brain tubulin polymerization preincubated for 1 mins followed by GTP addition and measured for 60 mins at 1 min interval by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50012278(VINBLASTINE SULFATE | (2ALPHA,2''BETA,3BETA,4ALPHA...)
Affinity DataIC50: 130nMAssay Description:In vitro inhibition of maximum porcine tubulin assembly rate after 20 min at 37 degrees CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50012278(VINBLASTINE SULFATE | (2ALPHA,2''BETA,3BETA,4ALPHA...)
Affinity DataIC50: 130nMAssay Description:Inhibition of tubulin polymerization in porcine brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50012278(VINBLASTINE SULFATE | (2ALPHA,2''BETA,3BETA,4ALPHA...)
Affinity DataIC50: 130nMAssay Description:Inhibition of pig brain tubulin polymerization after 30 mins by turbidimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50012278(VINBLASTINE SULFATE | (2ALPHA,2''BETA,3BETA,4ALPHA...)
Affinity DataIC50: 130nMAssay Description:Inhibition of pig brain tubulin polymerization after 30 mins by turbidimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50012278(VINBLASTINE SULFATE | (2ALPHA,2''BETA,3BETA,4ALPHA...)
Affinity DataIC50: 130nMAssay Description:Inhibition of pig tubulin polymerization determined after 45 mins at 37 degC by turbidimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50012278(VINBLASTINE SULFATE | (2ALPHA,2''BETA,3BETA,4ALPHA...)
Affinity DataIC50: 130nMAssay Description:Inhibition of porcine brain tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50012278(VINBLASTINE SULFATE | (2ALPHA,2''BETA,3BETA,4ALPHA...)
Affinity DataIC50: 130nMAssay Description:Inhibition of pig brain tubulin polymerization after 30 mins by turbidimetry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50500399(CHEMBL3746906)
Affinity DataIC50: 160nMAssay Description:Displacement of [3H]-colchicine from biotinylated porcine tubulin after 2 hrs by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50474288(CHEMBL112192)
Affinity DataIC50: 220nMAssay Description:In vitro inhibitory concentration required to displace [3H]colchicine from its binding site on tubulinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50477242(CHEMBL240468)
Affinity DataIC50: 290nMAssay Description:Inhibition of porcine brain tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50477251(CHEMBL429265)
Affinity DataIC50: 290nMAssay Description:Inhibition of porcine brain tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50035218(podophyllotoxin | CHEMBL61 | Podophyllinic acid la...)
Affinity DataIC50: 350nMAssay Description:In vitro inhibition of maximum porcine tubulin assembly rate after 20 min at 37 degrees CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50035218(podophyllotoxin | CHEMBL61 | Podophyllinic acid la...)
Affinity DataIC50: 350nMAssay Description:Inhibition of tubulin polymerization in porcine brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50035218(podophyllotoxin | CHEMBL61 | Podophyllinic acid la...)
Affinity DataIC50: 350nMAssay Description:Inhibition of pig brain tubulin polymerization after 30 mins by turbidimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50035218(podophyllotoxin | CHEMBL61 | Podophyllinic acid la...)
Affinity DataIC50: 350nMAssay Description:Inhibition of pig brain tubulin polymerization after 30 mins by turbidimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50035218(podophyllotoxin | CHEMBL61 | Podophyllinic acid la...)
Affinity DataIC50: 350nMAssay Description:Inhibition of pig tubulin polymerization determined after 45 mins at 37 degC by turbidimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50035218(podophyllotoxin | CHEMBL61 | Podophyllinic acid la...)
Affinity DataIC50: 350nMAssay Description:Inhibition of porcine brain tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50035218(podophyllotoxin | CHEMBL61 | Podophyllinic acid la...)
Affinity DataIC50: 350nMAssay Description:Inhibition of pig brain tubulin polymerization after 30 mins by turbidimetry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50469125(CHEMBL1210959)
Affinity DataIC50: 360nMAssay Description:Inhibition of pig brain tubulin polymerization after 30 mins by turbidimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50469121(CHEMBL1210876)
Affinity DataIC50: 360nMAssay Description:Inhibition of pig brain tubulin polymerization after 30 mins by turbidimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50482385(CHEMBL1210322)
Affinity DataIC50: 360nMAssay Description:Inhibition of pig brain tubulin polymerization after 30 mins by turbidimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50474300(CHEMBL116173)
Affinity DataIC50: 370nMAssay Description:In vitro inhibitory concentration required to displace [3H]colchicine from its binding site on TubulinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50476049(CHEMBL219102)
Affinity DataIC50: 380nMAssay Description:Inhibition of tubulin polymerization in porcine brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50482387(CHEMBL1209944)
Affinity DataIC50: 380nMAssay Description:Inhibition of pig brain tubulin polymerization after 30 mins by turbidimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50477244(CHEMBL237880)
Affinity DataIC50: 390nMAssay Description:Inhibition of porcine brain tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50504509(CHEMBL4452039)
Affinity DataIC50: 400nMAssay Description:Inhibition of pig brain tubulin polymerization in presence of GTP by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50479547(CHEMBL455138)
Affinity DataIC50: 400nMAssay Description:Displacement of [3H]Colchicine from pig biotinylated tubulin after 2 hrs by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
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