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Report error Found 3 of affinity data for UniProtKB/TrEMBL: P01223
TargetThyrotropin subunit beta(Bovine)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM60862(BDBM189328 | US9174940, 32)
Affinity DataIC50: 48nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetThyrotropin subunit beta(Bovine)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM189329(US9174940, Compound C | (+)-(1-Acetyl-4-methyl-4-p...)
Affinity DataIC50: 192nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetThyrotropin subunit beta(Bovine)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM189327(US9174940, Compound A | Hexanoic acid (Compound A))
Affinity DataIC50: 368nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent