Compile Data Set for Download or QSAR
Report error Found 4665 of affinity data for UniProtKB/TrEMBL: P00797
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50014096(1-Acetyl-pyrrolidine-2-carboxylic acid {1-[1-{1-[(...)
Affinity DataKd:  29nMAssay Description:Dissociation constant (Kd) of renin inhibitor was determined over a temperature range of 8-37 degree by the fluorescence displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50427041(CHEMBL2322210)
Affinity DataKd: >5.00E+5nMAssay Description:Binding affinity to human recombinant renin by NMR titration analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50291951((R)-2-(2-Amino-thiazol-4-ylmethyl)-N*1*-((1S,2R,3S...)
Affinity DataKon:  0.00133M-1s-1 Koff:  5.43s-1Assay Description:Component acylation rate constant by the compound against Renin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50084627(2-(2-Amino-thiazol-4-ylmethyl)-N*4*-cyclohexylmeth...)
Affinity DataKon:  0.000280M-1s-1 Koff:  5.93s-1Assay Description:Component acylation rate constant by the compound against Renin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50291952((R)-2-(2-Amino-thiazol-4-ylmethyl)-N*1*-((1S,2R,3S...)
Affinity DataKon:  0.00481M-1s-1 Koff:  2.07s-1Assay Description:Component acylation rate constant by the compound against Renin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50291953((R)-2-(2-Amino-thiazol-4-ylmethyl)-N*1*-((1S,2R,3S...)
Affinity DataKon:  0.00175M-1s-1 Koff:  2.28s-1Assay Description:Component acylation rate constant by the compound against Renin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50291954((R)-2-(2-Amino-thiazol-4-ylmethyl)-N*1*-((1S,2R,3S...)
Affinity DataKon:  0.00135M-1s-1 Koff:  6.68s-1Assay Description:Component acylation rate constant by the compound against Renin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50291955((R)-2-(2-Amino-thiazol-4-ylmethyl)-N*1*-((1S,2R,3S...)
Affinity DataKon:  0.000569M-1s-1 Koff:  1.22s-1Assay Description:Component acylation rate constant by the compound against Renin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50291956((R)-2-(2-Amino-thiazol-4-ylmethyl)-N*1*-((1S,2R,3S...)
Affinity DataKon:  0.00130M-1s-1 Koff:  2s-1Assay Description:Component acylation rate constant by the compound against Renin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50291957((R)-2-(2-Amino-thiazol-4-ylmethyl)-N*4*-cyclohepty...)
Affinity DataKon:  0.000234M-1s-1 Koff:  8.63s-1Assay Description:Component acylation rate constant by the compound against Renin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM18040(4-amino-N-{2-[2-({2-amino-6-ethyl-5-[4-(3-methoxyp...)
Affinity DataKd:  270nMAssay Description:Binding affinity to human recombinant renin by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM18041(N-[2-({2-amino-6-ethyl-5-[4-(3-methoxypropyl)-2,2-...)
Affinity DataKd:  79nMAssay Description:Binding affinity to human recombinant renin by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50427042(CHEMBL2322211)
Affinity DataKd: >5.00E+5nMAssay Description:Binding affinity to human recombinant renin by NMR titration analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50406401(U-77646E | CHEMBL2062122)
Affinity DataKd:  5.40nMAssay Description:Dissociation constant (Kd) of renin inhibitor was determined over a temperature range of 8-37 degree by the fluorescence displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50406402(U-80631E | CHEMBL2062126)
Affinity DataKd:  370nMAssay Description:Dissociation constant (Kd) of renin inhibitor was determined over a temperature range of 8-37 degree by the fluorescence displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50406403(U-72408E | CHEMBL2062121)
Affinity DataKd:  98nMAssay Description:Dissociation constant (Kd) of renin inhibitor was determined over a temperature range of 8-37 degree by the fluorescence displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50406404(U-62168E | CHEMBL2028834)
Affinity DataKd:  810nMAssay Description:Dissociation constant (Kd) of renin inhibitor was determined over a temperature range of 8-37 degree by the fluorescence displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50406405(U-72409E | CHEMBL2062124)
Affinity DataKd:  23nMAssay Description:Dissociation constant (Kd) of renin inhibitor was determined over a temperature range of 8-37 degree by the fluorescence displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50406406(U-72407E | CHEMBL2062129)
Affinity DataKd:  204nMAssay Description:Dissociation constant (Kd) of renin inhibitor was determined over a temperature range of 8-37 degree by the fluorescence displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50406407(U-80215E | CHEMBL2062127)
Affinity DataKd:  1.00E+3nMAssay Description:Dissociation constant (Kd) of renin inhibitor was determined over a temperature range of 8-37 degree by the fluorescence displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50406408(U-77451E | CHEMBL2062128)
Affinity DataKd:  2.5nMAssay Description:Dissociation constant (Kd) of renin inhibitor was determined over a temperature range of 8-37 degree by the fluorescence displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50025900(Iva-His-Pro-Phe-His-Sta-Ile-Phe-NH2 | CHEMBL438100)
Affinity DataKd:  1.70nMAssay Description:Dissociation constant (Kd) of renin inhibitor was determined over a temperature range of 8-37 degree by the fluorescence displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50022859(Pro-His-Prp-Phe-His-Leu(psi)[CH2NH]Val-Ile-His-Lys...)
Affinity DataKd:  8nMAssay Description:Dissociation constant (Kd) of renin inhibitor was determined over a temperature range of 8-37 degree by the fluorescence displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50406409(U-73777E | CHEMBL2062125)
Affinity DataKd:  220nMAssay Description:Dissociation constant (Kd) of renin inhibitor was determined over a temperature range of 8-37 degree by the fluorescence displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50406410(U-77647E | CHEMBL2062123)
Affinity DataKd:  1.30nMAssay Description:Dissociation constant (Kd) of renin inhibitor was determined over a temperature range of 8-37 degree by the fluorescence displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50077669(CHEMBL31601 | 2-Benzyl-N-[1-(1-cyclohexylmethyl-3-...)
Affinity DataKd:  0.131nMAssay Description:Binding affinity to renin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50340417(5-(3-(((3R,4S)-N-cyclopropyl-4-(4-(2-(2,6-dichloro...)
Affinity DataIC50: 0.0100nMpH: 7.4Assay Description:Inhibition of human recombinant renin in PBS buffer using tetradecapeptide at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50340419(1-(2-(3-(((3R,4S)-N-cyclopropyl-4-(4-(2-(2,6-dichl...)
Affinity DataIC50: 0.0100nMpH: 7.4Assay Description:Inhibition of human recombinant renin in PBS buffer using tetradecapeptide at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50340421((3R,4S)-N-cyclopropyl-4-(4-(2-(2,6-dichloro-4-meth...)
Affinity DataIC50: 0.0100nMpH: 7.4Assay Description:Inhibition of human recombinant renin in PBS buffer using tetradecapeptide at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50346987(CHEMBL1796073)
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of human recombinant renin using Q-FRET substrate after 3 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50340416(4-(3-(((3R,4S)-N-cyclopropyl-4-(4-(2-(2,6-dichloro...)
Affinity DataIC50: 0.0200nMpH: 7.4Assay Description:Inhibition of human recombinant renin in PBS buffer using tetradecapeptide at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50340418(4-(3-(((3R,4S)-N-cyclopropyl-4-(4-(2-(2,6-dichloro...)
Affinity DataIC50: 0.0200nMpH: 7.4Assay Description:Inhibition of human recombinant renin in PBS buffer using tetradecapeptide at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50340407((3R,4S)-N-cyclopropyl-4-(4-(2-(2,6-dichloro-4-meth...)
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of renin in human plasma using Q-FRET substrate pretreated for 10 mins before substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50340407((3R,4S)-N-cyclopropyl-4-(4-(2-(2,6-dichloro-4-meth...)
Affinity DataIC50: 0.0210nMpH: 7.4Assay Description:Inhibition of human recombinant renin in PBS buffer using tetradecapeptide at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50340410((3R,4S)-N-cyclopropyl-4-(4-(2-(2,6-dichloro-4-meth...)
Affinity DataIC50: 0.0220nMpH: 7.4Assay Description:Inhibition of human recombinant renin in PBS buffer using tetradecapeptide at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50077669(CHEMBL31601 | 2-Benzyl-N-[1-(1-cyclohexylmethyl-3-...)
Affinity DataIC50: 0.0250nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50340413((1S,2S)-2-((3-(((3R,4S)-N-cyclopropyl-4-(4-(2-(2,6...)
Affinity DataIC50: 0.0270nMpH: 7.4Assay Description:Inhibition of human recombinant renin in PBS buffer using tetradecapeptide at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50340406((3R,4S)-N-(3-((1-(cyanomethyl)cyclopropyl)methoxy)...)
Affinity DataIC50: 0.0280nMpH: 7.4Assay Description:Inhibition of human recombinant renin in PBS buffer using tetradecapeptide at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50340409((3R,4S)-N-cyclopropyl-4-(4-(2-(2,6-dichloro-4-meth...)
Affinity DataIC50: 0.0280nMpH: 7.4Assay Description:Inhibition of human recombinant renin in PBS buffer using tetradecapeptide at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50403370(CP-71362 | CHEMBL2052021)
Affinity DataIC50: 0.0300nMAssay Description:Compound was tested for its inhibitory activity against dog plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50340422((3R,4S)-N-(3-((1-((2H-tetrazol-5-yl)methyl)cyclopr...)
Affinity DataIC50: 0.0300nMpH: 7.4Assay Description:Inhibition of human recombinant renin in PBS buffer using tetradecapeptide at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50355509(CHEMBL1910311)
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of human recombinant renin using DNP-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-D,L-Amp as Q-FRET substrate after 3 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50330345(N-(2-(7-(((3R,4R)-4-(4-(3-(2-methoxybenzyloxy)prop...)
Affinity DataIC50: 0.0390nMAssay Description:Inhibition of human recombinant renin in bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50195783(CHEMBL3907708)
Affinity DataIC50: 0.0390nMAssay Description:Inhibition of recombinant human preprorenin expressed in human 293F cells using angiotensinogen as substrate preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50195783(CHEMBL3907708)
Affinity DataIC50: 0.0390nMAssay Description:Inhibition of recombinant human preprorenin expressed in human 293F cells using angiotensinogen as substrate preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50330345(N-(2-(7-(((3R,4R)-4-(4-(3-(2-methoxybenzyloxy)prop...)
Affinity DataIC50: 0.0390nMAssay Description:Inhibition of human recombinant rennin in buffer assessed as accumulation of angiotensin 1 using human tetradecapeptide by immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50327295(N-(2-(4'-(1-amino-3-(4-(2-(2,6-dichloro-4-methylph...)
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of human recombinant renin in phosphate bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50328867(rac-5-chloro-4-((N-cyclopropyl-4-(4-(2-(2,6-dichlo...)
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of renin in bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50340414(2-(1-((3-(((3R,4S)-N-cyclopropyl-4-(4-(2-(2,6-dich...)
Affinity DataIC50: 0.0400nMpH: 7.4Assay Description:Inhibition of human recombinant renin in PBS buffer using tetradecapeptide at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetRenin(Human)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50355517(CHEMBL1910319)
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of human recombinant renin using DNP-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-D,L-Amp as Q-FRET substrate after 3 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
Displayed 1 to 50 (of 4665 total ) | Next | Last >>
Jump to: