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TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50033766(CHEMBL3358149)
Affinity DataKd: <100nMAssay Description:Binding affinity to recombinant F13A (unknown origin) by microscale thermophoresis methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50033803(CHEMBL3358150)
Affinity DataKd:  800nMAssay Description:Binding affinity to recombinant F13A (unknown origin) by microscale thermophoresis methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandPNGBDBM50608716(CHEMBL5269322)
Affinity DataKd:  2.53E+4nMAssay Description:Binding affinity to human coagulation factor XIIIa by Spectrofluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50083722(CHEMBL3423198)
Affinity DataIC50: 4nMAssay Description:Inhibition of thrombin-activated F13-A (unknown origin) in plasma assessed as inhibition of fibrin clot formation after 7 mins by biotin incorporatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50083725(CHEMBL3423195)
Affinity DataIC50: 4nMAssay Description:Inhibition of thrombin-activated F13-A (unknown origin) in plasma assessed as inhibition of fibrin clot formation after 7 mins by biotin incorporatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetCoagulation factor XIII A/B chain(Human)
Zedira

US Patent
LigandPNGBDBM577483(US11472838, Compound 5)
Affinity DataIC50: 4nMAssay Description:The most relevant off-targets are the transglutaminase isoenzymes especially tissue transglutaminase (TG2) because the enzyme is ubiquitously express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A/B chain(Human)
Zedira

US Patent
LigandPNGBDBM577483(US11472838, Compound 5)
Affinity DataIC50: 10nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577509(US11472838, Compound 27 | US11472838, Compound 31a...)
Affinity DataIC50: 10nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577537(US11472838, Compound Ref. 14)
Affinity DataIC50: 10nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577540(US11472838, Compound Ref. 16)
Affinity DataIC50: 10nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577546(US11472838, Compound Ref. 21)
Affinity DataIC50: 10nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50245478(CHEMBL4081588 | US11472838, Compound Ref. 25)
Affinity DataIC50: 10nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577484(US11472838, Compound 1a/b)
Affinity DataIC50: 11nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577511(US11472838, Compound 29 | US11472838, Compound 32a...)
Affinity DataIC50: 12nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577487(US11472838, Compound 4)
Affinity DataIC50: 13nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577512(US11472838, Compound 30)
Affinity DataIC50: 15nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577483(US11472838, Compound 5)
Affinity DataIC50: 16nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577485(US11472838, Compound 2a/b)
Affinity DataIC50: 16nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577483(US11472838, Compound 5)
Affinity DataIC50: 16nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577488(US11472838, Compound 6)
Affinity DataIC50: 17nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577506(US11472838, Compound 24a/b)
Affinity DataIC50: 18nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577486(US11472838, Compound 3)
Affinity DataIC50: 20nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577507(US11472838, Compound 25a/b)
Affinity DataIC50: 20nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577489(US11472838, Compound 7a/b)
Affinity DataIC50: 21nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577490(US11472838, Compound 8a/b)
Affinity DataIC50: 21nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577483(US11472838, Compound 5)
Affinity DataIC50: 24nMAssay Description:The most relevant off-targets are the transglutaminase isoenzymes especially tissue transglutaminase (TG2) because the enzyme is ubiquitously express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577483(US11472838, Compound 5)
Affinity DataIC50: 24nMAssay Description:The most relevant off-targets are the transglutaminase isoenzymes especially tissue transglutaminase (TG2) because the enzyme is ubiquitously express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577511(US11472838, Compound 29 | US11472838, Compound 32a...)
Affinity DataIC50: 24nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577496(US11472838, Compound 14a/b)
Affinity DataIC50: 26nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandPNGBDBM50608714(CHEMBL5281897)
Affinity DataIC50: 26nMAssay Description:Inhibition of human plasma coagulation factor XIIIa by fluorescence spectrophotometeric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577509(US11472838, Compound 27 | US11472838, Compound 31a...)
Affinity DataIC50: 27nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandPNGBDBM50608719(CHEMBL5269766)
Affinity DataIC50: 29nMAssay Description:Inhibition of human recombinant coagulation factor XIIIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577547(US11472838, Compound 45a/b)
Affinity DataIC50: 35nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577510(US11472838, Compound 28)
Affinity DataIC50: 36nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50420503(CHEMBL2086505)
Affinity DataIC50: 39nMAssay Description:Inhibition of thrombin activated human F13a by fluorescent transamidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577530(US11472838, Compound 39a/b)
Affinity DataIC50: 39nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577499(US11472838, Compound 17a/b)
Affinity DataIC50: 41nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577518(US11472838, Compound 36a/b)
Affinity DataIC50: 41nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577492(US11472838, Compound 10a/b)
Affinity DataIC50: 42nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577504(US11472838, Compound 22a/b)
Affinity DataIC50: 42nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577508(US11472838, Compound 26a/b)
Affinity DataIC50: 43nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577528(US11472838, Compound 38)
Affinity DataIC50: 47nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50083726(CHEMBL3423194)
Affinity DataIC50: 48nMAssay Description:Inhibition of thrombin-activated F13-A (unknown origin) in plasma assessed as inhibition of fibrin clot formation after 7 mins by biotin incorporatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50420457(CHEMBL2086890)
Affinity DataIC50: 51nMAssay Description:Inhibition of thrombin activated human F13a by fluorescent transamidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577494(US11472838, Compound 12a/b)
Affinity DataIC50: 51nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50083728(CHEMBL3423193)
Affinity DataIC50: 55nMAssay Description:Inhibition of thrombin-activated F13-A (unknown origin) in plasma assessed as inhibition of fibrin clot formation after 7 mins by biotin incorporatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577534(US11472838, Compound 42a/b)
Affinity DataIC50: 56nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577549(US11472838, Compound Ref. 23)
Affinity DataIC50: 56nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM577503(US11472838, Compound 21a/b)
Affinity DataIC50: 59nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XIII A chain(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50420458(CHEMBL2086891)
Affinity DataIC50: 66nMAssay Description:Inhibition of thrombin activated human F13a by fluorescent transamidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
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