Compile Data Set for Download or QSAR
Report error Found 142 of affinity data for UniProtKB/TrEMBL: P00371
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50260723(1H-pyrrole-2-carboxylic acid | pyrrole-2-carboxyli...)
Affinity DataKd:  2.60E+4nMAssay Description:Binding affinity to pig kidney DAAO using D-alanine as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50460188(CHEMBL1886565)
Affinity DataKd:  4.59E+3nMAssay Description:Binding affinity to pig kidney DAAO by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM22821(7-methyl-2,3-dihydro-1H-indole-2,3-dione | Isatin-...)
Affinity DataKd:  8.23E+3nMAssay Description:Binding affinity to pig kidney DAAO by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50008990(CHEMBL276725 | 1H-indazol-3-ol | 1,2-Dihydro-indaz...)
Affinity DataKd:  4.43E+3nMAssay Description:Binding affinity to pig kidney DAAO by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50460190(CHEMBL4225412)
Affinity DataKd:  1.20E+3nMAssay Description:Binding affinity to pig kidney DAAO by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50460191(CHEMBL4225929)
Affinity DataKd:  1.00E+3nMAssay Description:Binding affinity to pig kidney DAAO by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50460189(CHEMBL4225931)
Affinity DataKd:  3.31E+3nMAssay Description:Binding affinity to pig kidney DAAO by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170230(CHEMBL445990)
Affinity DataKd:  870nMAssay Description:Binding affinity to pig kidney DAAO by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50232880(Benzo[D]Isoxazol-3-Ol | CHEMBL444173)
Affinity DataKd:  440nMAssay Description:Binding affinity to pig kidney DAAO by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50460192(CHEMBL4224785)
Affinity DataKd:  2.00E+3nMAssay Description:Binding affinity to pig kidney DAAO by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50460193(CHEMBL4227374)
Affinity DataKd:  780nMAssay Description:Binding affinity to pig kidney DAAO by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50460194(CHEMBL2001613)
Affinity DataKd:  3.29E+3nMAssay Description:Binding affinity to pig kidney DAAO by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM31148(3-hydroxyquinolin-2(1H)-one, 2 | US9701638, 1)
Affinity DataKd:  150nMAssay Description:Binding affinity to pig kidney DAAO by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM406232(6-(naphthalen-1-ylmethyl)-3-oxo-2,3-dihydropyridaz...)
Affinity DataIC50: 55nMAssay Description:The pkDAAO (porcine kidney DAAO) activity was measured by using D-Proine as a substrate to produce hydrogen peroxide (H2O2). The produced H2O2 would ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
Go to US Patent

TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM406233(6-(naphthalen-1-ylmethyl)-3-oxo-2,3-dihydropyridaz...)
Affinity DataIC50: 55nMAssay Description:The pkDAAO (porcine kidney DAAO) activity was measured by using D-Proine as a substrate to produce hydrogen peroxide (H2O2). The produced H2O2 would ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
Go to US Patent

TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM406234(6-(naphthalen-1-ylmethyl)-3-oxo-2,3-dihydropyridaz...)
Affinity DataIC50: 55nMAssay Description:The pkDAAO (porcine kidney DAAO) activity was measured by using D-Proine as a substrate to produce hydrogen peroxide (H2O2). The produced H2O2 would ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
Go to US Patent

TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM406235(6-(naphthalen-1-ylmethyl)-3-oxo-2,3-dihydropyridaz...)
Affinity DataIC50: 55nMAssay Description:The pkDAAO (porcine kidney DAAO) activity was measured by using D-Proine as a substrate to produce hydrogen peroxide (H2O2). The produced H2O2 would ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
Go to US Patent

TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM406236(US10336724, Compound Table 1.16)
Affinity DataIC50: 55nMAssay Description:The pkDAAO (porcine kidney DAAO) activity was measured by using D-Proine as a substrate to produce hydrogen peroxide (H2O2). The produced H2O2 would ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
Go to US Patent

TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM406237(US10336724, Compound Table 1.17)
Affinity DataIC50: 55nMAssay Description:The pkDAAO (porcine kidney DAAO) activity was measured by using D-Proine as a substrate to produce hydrogen peroxide (H2O2). The produced H2O2 would ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
Go to US Patent

TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM406238(US10336724, Compound Table 1.18)
Affinity DataIC50: 55nMAssay Description:The pkDAAO (porcine kidney DAAO) activity was measured by using D-Proine as a substrate to produce hydrogen peroxide (H2O2). The produced H2O2 would ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
Go to US Patent

TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM406239(US10336724, Compound Table 1.19)
Affinity DataIC50: 55nMAssay Description:The pkDAAO (porcine kidney DAAO) activity was measured by using D-Proine as a substrate to produce hydrogen peroxide (H2O2). The produced H2O2 would ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
Go to US Patent

TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM31148(3-hydroxyquinolin-2(1H)-one, 2 | US9701638, 1)
Affinity DataIC50: 100nMAssay Description:Inhibition of DAAO in porcine kidney homogenate using D-alanine as substrate assessed as pyruvate production incubated for 5 mins by microplate reade...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2017
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170227(CHEMBL3805642)
Affinity DataIC50: 150nMAssay Description:Inhibition of DAAO in porcine kidney homogenate using D-alanine as substrate assessed as pyruvate production incubated for 5 mins by microplate reade...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2017
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170229(CHEMBL3804851)
Affinity DataIC50: 180nMAssay Description:Inhibition of DAAO in porcine kidney homogenate using D-alanine as substrate assessed as pyruvate production incubated for 5 mins by microplate reade...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2017
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM23174(CHEMBL445990 | 6-chloro-1,2-benzoxazol-3-ol | 6-ch...)
Affinity DataIC50: 188nMpH: 8.5 T: 2°CAssay Description:D-amino acid oxidase (DAAO) was assayed in a 96-well plate format. D-serine was oxidatively deaminated by porcine D-amino acid oxidase in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50393043(CHEMBL2152732)
Affinity DataIC50: 200nMAssay Description:Inhibition of pig DAAO using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170230(CHEMBL445990)
Affinity DataIC50: 210nMAssay Description:Inhibition of DAAO in porcine kidney homogenate using D-alanine as substrate assessed as pyruvate production incubated for 5 mins by microplate reade...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2017
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170228(CHEMBL3804953)
Affinity DataIC50: 220nMAssay Description:Inhibition of DAAO in porcine kidney homogenate using D-alanine as substrate assessed as pyruvate production incubated for 5 mins by microplate reade...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2017
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170225(CHEMBL3805223)
Affinity DataIC50: 240nMAssay Description:Inhibition of DAAO in porcine kidney homogenate using D-alanine as substrate assessed as pyruvate production incubated for 5 mins by microplate reade...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2017
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170226(CHEMBL92084)
Affinity DataIC50: 260nMAssay Description:Inhibition of DAAO in porcine kidney homogenate using D-alanine as substrate assessed as pyruvate production incubated for 5 mins by microplate reade...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2017
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM23175(6-methyl-1,2-benzoxazol-3-ol | Benzo[d]isoxazol-3-...)
Affinity DataIC50: 269nMpH: 8.5 T: 2°CAssay Description:D-amino acid oxidase (DAAO) was assayed in a 96-well plate format. D-serine was oxidatively deaminated by porcine D-amino acid oxidase in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM258351(US9505753, 10t)
Affinity DataIC50: 300nMpH: 8.5 T: 2°CAssay Description:A reliable 96-well plate D-amino acid oxidase (DAAO) assay was developed based on previously published reports (J. Biol. Chem. 277: 27782 (2002)). Br...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2017
Entry Details
Go to US Patent

TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM406228(5-chloro-2-oxo-1,2-dihydroquinolin-3-yl 3-(4-chlor...)
Affinity DataIC50: 300nMAssay Description:The pkDAAO (porcine kidney DAAO) activity was measured by using D-Proine as a substrate to produce hydrogen peroxide (H2O2). The produced H2O2 would ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
Go to US Patent

TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50393061(CHEMBL2152722)
Affinity DataIC50: 400nMAssay Description:Inhibition of pig DAAO using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50393063(CHEMBL2152724)
Affinity DataIC50: 400nMAssay Description:Inhibition of pig DAAO using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50393045(CHEMBL2152734)
Affinity DataIC50: 400nMAssay Description:Inhibition of pig DAAO using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170234(CHEMBL329680)
Affinity DataIC50: 400nMAssay Description:Inhibition of DAAO in porcine kidney homogenate using D-alanine as substrate assessed as pyruvate production incubated for 5 mins by microplate reade...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2017
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM23173(6-fluoro-1,2-benzoxazol-3-ol | Benzo[d]isoxazol-3-...)
Affinity DataIC50: 444nMpH: 8.5 T: 2°CAssay Description:D-amino acid oxidase (DAAO) was assayed in a 96-well plate format. D-serine was oxidatively deaminated by porcine D-amino acid oxidase in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170246(CHEMBL3806244)
Affinity DataIC50: 460nMAssay Description:Inhibition of DAAO in porcine kidney homogenate using D-alanine as substrate assessed as pyruvate production incubated for 5 mins by microplate reade...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2017
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170232(CHEMBL3805370)
Affinity DataIC50: 480nMAssay Description:Inhibition of DAAO in porcine kidney homogenate using D-alanine as substrate assessed as pyruvate production incubated for 5 mins by microplate reade...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2017
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50393060(CHEMBL2152721)
Affinity DataIC50: 500nMAssay Description:Inhibition of pig DAAO using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170274(CHEMBL3804949)
Affinity DataIC50: 520nMAssay Description:Inhibition of DAAO in porcine kidney homogenate using D-alanine as substrate assessed as pyruvate production incubated for 5 mins by microplate reade...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2017
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170231(CHEMBL3806101)
Affinity DataIC50: 530nMAssay Description:Inhibition of DAAO in porcine kidney homogenate using D-alanine as substrate assessed as pyruvate production incubated for 5 mins by microplate reade...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2017
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM406224(5-chloro-2-oxo-1,2-dihydroquinolin-3-yl 3-phenethy...)
Affinity DataIC50: 550nMAssay Description:The pkDAAO (porcine kidney DAAO) activity was measured by using D-Proine as a substrate to produce hydrogen peroxide (H2O2). The produced H2O2 would ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
Go to US Patent

TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM406229(5-(((3,4-dichlorophenyl) thio) methyl)-2-oxo-1,2-d...)
Affinity DataIC50: 550nMAssay Description:The pkDAAO (porcine kidney DAAO) activity was measured by using D-Proine as a substrate to produce hydrogen peroxide (H2O2). The produced H2O2 would ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
Go to US Patent

TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM23170(5-bromo-1,2-benzoxazol-3-ol | Benzo[d]isoxazol-3-o...)
Affinity DataIC50: 599nMpH: 8.5 T: 2°CAssay Description:D-amino acid oxidase (DAAO) was assayed in a 96-well plate format. D-serine was oxidatively deaminated by porcine D-amino acid oxidase in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50393051(CHEMBL2152740)
Affinity DataIC50: 600nMAssay Description:Inhibition of pig DAAO using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM258352(US9505753, 10u)
Affinity DataIC50: 600nMpH: 8.5 T: 2°CAssay Description:A reliable 96-well plate D-amino acid oxidase (DAAO) assay was developed based on previously published reports (J. Biol. Chem. 277: 27782 (2002)). Br...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2017
Entry Details
Go to US Patent

TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170277(CHEMBL3805717)
Affinity DataIC50: 630nMAssay Description:Inhibition of DAAO in porcine kidney homogenate using D-alanine as substrate assessed as pyruvate production incubated for 5 mins by microplate reade...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2017
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170233(CHEMBL3805789)
Affinity DataIC50: 650nMAssay Description:Inhibition of DAAO in porcine kidney homogenate using D-alanine as substrate assessed as pyruvate production incubated for 5 mins by microplate reade...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2017
Entry Details Article
PubMed
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