Compile Data Set for Download or QSAR
Report error Found 124 of affinity data for UniProtKB/TrEMBL: O94788
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50567384(CHEMBL4849586)
Affinity DataIC50: 21nMAssay Description:Inhibition of human ALDH1A2 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50567363(CHEMBL4876602)
Affinity DataIC50: 40nMAssay Description:Inhibition of human ALDH1A2 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM689520(US12054475, Compound 142)
Affinity DataIC50: 57nMAssay Description:Recombinant protein extraction: pET-Aldh1a2 transformed BL21-DE3 cultures induced at 20° C. for 19 h with 0.3 mM IPTG rocking. Cultures were spun at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50567385(CHEMBL4846203)
Affinity DataIC50: 58nMAssay Description:Inhibition of human ALDH1A2 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50567372(CHEMBL4875157)
Affinity DataIC50: 63nMAssay Description:Inhibition of human ALDH1A2 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50236909(CHEMBL4090473)
Affinity DataIC50: 65nMAssay Description:Inhibition of full length recombinant human ALDH1A2 expressed in Escherichia coli BL21(DE3) assessed as reduction in dehydrogenase activity by measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2019
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50567383(CHEMBL4847114)
Affinity DataIC50: 65nMAssay Description:Inhibition of human ALDH1A2 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50236908(CHEMBL1562069)
Affinity DataIC50: 69nMAssay Description:Inhibition of full length recombinant human ALDH1A2 expressed in Escherichia coli BL21(DE3) assessed as reduction in dehydrogenase activity by measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2019
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM689538(US12054475, Compound 168)
Affinity DataIC50: 70nMAssay Description:Recombinant protein extraction: pET-Aldh1a2 transformed BL21-DE3 cultures induced at 20° C. for 19 h with 0.3 mM IPTG rocking. Cultures were spun at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM689526(US12054475, Compound 151)
Affinity DataIC50: 75nMAssay Description:Recombinant protein extraction: pET-Aldh1a2 transformed BL21-DE3 cultures induced at 20° C. for 19 h with 0.3 mM IPTG rocking. Cultures were spun at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50567382(CHEMBL4859904)
Affinity DataIC50: 80nMAssay Description:Inhibition of human ALDH1A2 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM689524(US12054475, Compound 149)
Affinity DataIC50: 87nMAssay Description:Recombinant protein extraction: pET-Aldh1a2 transformed BL21-DE3 cultures induced at 20° C. for 19 h with 0.3 mM IPTG rocking. Cultures were spun at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50567373(CHEMBL4855442)
Affinity DataIC50: 89nMAssay Description:Inhibition of human ALDH1A2 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM689537(US12054475, Compound 161)
Affinity DataIC50: 89nMAssay Description:Recombinant protein extraction: pET-Aldh1a2 transformed BL21-DE3 cultures induced at 20° C. for 19 h with 0.3 mM IPTG rocking. Cultures were spun at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM689519(US12054475, Compound 140)
Affinity DataIC50: 99nMAssay Description:Recombinant protein extraction: pET-Aldh1a2 transformed BL21-DE3 cultures induced at 20° C. for 19 h with 0.3 mM IPTG rocking. Cultures were spun at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50406342(CHEMBL5283146)
Affinity DataIC50: 100nMAssay Description:Inhibition of full length human ALDH1A2 using propionaldehyde as substrate preincubated for 30 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50406343(CHEMBL5269320)
Affinity DataIC50: 100nMAssay Description:Inhibition of full length human ALDH1A2 using propionaldehyde as substrate preincubated for 30 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50567376(CHEMBL4848831)
Affinity DataIC50: 100nMAssay Description:Inhibition of human ALDH1A2 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50567378(CHEMBL4846491)
Affinity DataIC50: 108nMAssay Description:Inhibition of human ALDH1A2 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50567361(CHEMBL4862833)
Affinity DataIC50: 110nMAssay Description:Inhibition of human ALDH1A2 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50567362(CHEMBL4848258)
Affinity DataIC50: 110nMAssay Description:Inhibition of human ALDH1A2 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50567386(CHEMBL4861872)
Affinity DataIC50: 112nMAssay Description:Inhibition of human ALDH1A2 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM689529(US12054475, Compound 145)
Affinity DataIC50: 120nMAssay Description:Recombinant protein extraction: pET-Aldh1a2 transformed BL21-DE3 cultures induced at 20° C. for 19 h with 0.3 mM IPTG rocking. Cultures were spun at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM689533(US12054475, Compound 150)
Affinity DataIC50: 121nMAssay Description:Recombinant protein extraction: pET-Aldh1a2 transformed BL21-DE3 cultures induced at 20° C. for 19 h with 0.3 mM IPTG rocking. Cultures were spun at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50236905(CHEMBL1349972)
Affinity DataIC50: 130nMAssay Description:Inhibition of full length recombinant human ALDH1A2 expressed in Escherichia coli BL21(DE3) assessed as reduction in dehydrogenase activity by measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2019
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50567377(CHEMBL4874309)
Affinity DataIC50: 136nMAssay Description:Inhibition of human ALDH1A2 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50459603(CHEMBL4213331)
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant ALDH1A2 assessed as reduction in of NAD(P)H formation incubated for 2 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50459603(CHEMBL4213331)
Affinity DataIC50: 150nMAssay Description:Inhibition of human ALDH1A2 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM689532(US12054475, Compound 160)
Affinity DataIC50: 163nMAssay Description:Recombinant protein extraction: pET-Aldh1a2 transformed BL21-DE3 cultures induced at 20° C. for 19 h with 0.3 mM IPTG rocking. Cultures were spun at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50567369(CHEMBL4873090)
Affinity DataIC50: 170nMAssay Description:Inhibition of human ALDH1A2 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50567366(CHEMBL4876076)
Affinity DataIC50: 179nMAssay Description:Inhibition of human ALDH1A2 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50466622(CHEMBL4286209)
Affinity DataIC50: 191nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human RALDH2 using RAL as substrate preincubated for 20 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50567381(CHEMBL4867380)
Affinity DataIC50: 216nMAssay Description:Inhibition of human ALDH1A2 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50459602(CHEMBL4216790)
Affinity DataIC50: 230nMAssay Description:Inhibition of human recombinant ALDH1A2 assessed as reduction in of NAD(P)H formation incubated for 2 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50567352(CHEMBL4873315)
Affinity DataIC50: 240nMAssay Description:Inhibition of human ALDH1A2 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50459588(CHEMBL4210115)
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant ALDH1A2 assessed as reduction in of NAD(P)H formation incubated for 2 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50459588(CHEMBL4210115)
Affinity DataIC50: 250nMAssay Description:Inhibition of human ALDH1A2 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50567371(CHEMBL4868666)
Affinity DataIC50: 270nMAssay Description:Inhibition of human ALDH1A2 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM689525(US12054475, Compound 141)
Affinity DataIC50: 289nMAssay Description:Recombinant protein extraction: pET-Aldh1a2 transformed BL21-DE3 cultures induced at 20° C. for 19 h with 0.3 mM IPTG rocking. Cultures were spun at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50236899(CHEMBL4099822)
Affinity DataIC50: 300nMAssay Description:Inhibition of full length recombinant human ALDH1A2 expressed in Escherichia coli BL21(DE3) assessed as reduction in dehydrogenase activity by measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2019
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50567367(CHEMBL4863668)
Affinity DataIC50: 300nMAssay Description:Inhibition of human ALDH1A2 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM689521(US12054475, Compound 144)
Affinity DataIC50: 304nMAssay Description:Recombinant protein extraction: pET-Aldh1a2 transformed BL21-DE3 cultures induced at 20° C. for 19 h with 0.3 mM IPTG rocking. Cultures were spun at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50236900(CHEMBL4072941)
Affinity DataIC50: 330nMAssay Description:Inhibition of full length recombinant human ALDH1A2 expressed in Escherichia coli BL21(DE3) assessed as reduction in dehydrogenase activity by measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2019
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50459613(CHEMBL4214509)
Affinity DataIC50: 340nMAssay Description:Inhibition of human recombinant ALDH1A2 assessed as reduction in of NAD(P)H formation incubated for 2 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM689522(US12054475, Compound 146)
Affinity DataIC50: 356nMAssay Description:Recombinant protein extraction: pET-Aldh1a2 transformed BL21-DE3 cultures induced at 20° C. for 19 h with 0.3 mM IPTG rocking. Cultures were spun at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM689516(US12054475, Compound 53)
Affinity DataIC50: 374nMAssay Description:Recombinant protein extraction: pET-Aldh1a2 transformed BL21-DE3 cultures induced at 20° C. for 19 h with 0.3 mM IPTG rocking. Cultures were spun at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50567374(CHEMBL4849624)
Affinity DataIC50: 380nMAssay Description:Inhibition of human ALDH1A2 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50567370(CHEMBL4860590)
Affinity DataIC50: 400nMAssay Description:Inhibition of human ALDH1A2 assessed as NADH formation using propionaldehyde as substrate by spectrophotometeryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM689512(US12054475, Compound 77)
Affinity DataIC50: 415nMAssay Description:Recombinant protein extraction: pET-Aldh1a2 transformed BL21-DE3 cultures induced at 20° C. for 19 h with 0.3 mM IPTG rocking. Cultures were spun at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

TargetRetinal dehydrogenase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM689531(US12054475, Compound 147)
Affinity DataIC50: 431nMAssay Description:Recombinant protein extraction: pET-Aldh1a2 transformed BL21-DE3 cultures induced at 20° C. for 19 h with 0.3 mM IPTG rocking. Cultures were spun at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent

Displayed 1 to 50 (of 124 total ) | Next | Last >>
Jump to: