Compile Data Set for Download or QSAR
Report error Found 41 of affinity data for UniProtKB/TrEMBL: O88319
TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50130880(pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-L...)
Affinity DataEC50:  2nMAssay Description:Agonist activity at NTR1 in mouse N1E-115 cells assessed as increase in intracellular calcium concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50280251(UK-73093 | 4-Methyl-N-[2-(3-oxo-1-phenyl-1,3-dihyd...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory concentration required for the displacement of [3H]NT from neurotensin receptor in mouse; value ranges from 4-6 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50281791(Ac-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH | CHEMBL...)
Affinity DataKi:  0.0130nMAssay Description:Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50240845(2-{(S)-2-[2-({(S)-1-[(S)-2-((S)-2-Amino-5-guanidin...)
Affinity DataKi:  0.0180nMAssay Description:Binding affinity to NTR1 in mouse brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50240845(2-{(S)-2-[2-({(S)-1-[(S)-2-((S)-2-Amino-5-guanidin...)
Affinity DataKi:  0.0180nMAssay Description:Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50281781(Ac-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH | CHEMBL2645...)
Affinity DataKi:  0.0240nMAssay Description:Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50286859(2-{2-[(S)-2-({1-[(S)-6-Amino-2-((S)-(S)-2,6-diamin...)
Affinity DataKi:  0.0600nMAssay Description:Compound was tested in vitro for its binding affinity against Neurotensin Receptor after peripheral administrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50240339(CHEMBL266571 | Neurotensin 2 | 2-{(R)-(S)-2-[(S)-2...)
Affinity DataKi:  0.0640nMAssay Description:Compound was tested in vitro for its binding affinity against Neurotensin Receptor after peripheral administrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50286864((S)-2-{(S)-2-[(S)-2-({(R)-1-[5-Guanidino-2-(3-guan...)
Affinity DataKi:  0.100nMAssay Description:Compound was tested in vitro for its binding affinity against Neurotensin Receptor after peripheral administrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50281785((S)-2-{2-[(S)-2-{[(S)-1-((S)-2-{(S)-2-[((S)-1-Acet...)
Affinity DataKi:  0.100nMAssay Description:Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50240339(CHEMBL266571 | Neurotensin 2 | 2-{(R)-(S)-2-[(S)-2...)
Affinity DataKi:  0.110nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2012
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50281793(Ac-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu...)
Affinity DataKi:  0.110nMAssay Description:Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50281795(Ac-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH | CH...)
Affinity DataKi:  0.120nMAssay Description:Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50240844((S)-2-{2-[(S)-2-({(S)-1-[(S)-2-((S)-2-Acetylamino-...)
Affinity DataKi:  0.130nMAssay Description:Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50366427(CHEMBL1793865)
Affinity DataKi:  0.150nMAssay Description:Compound was tested in vitro for its binding affinity against Neurotensin Receptor after peripheral administrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50130880(pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-L...)
Affinity DataKi:  0.170nMAssay Description:Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50281784(Ac-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH ...)
Affinity DataKi:  0.210nMAssay Description:Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50281787((1S,4R)-2-{2-[2-({(S)-1-[(S)-2-((S)-2-Amino-propio...)
Affinity DataKi:  0.25nMAssay Description:Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM82078(NSC_128644 | CAS_55508-42-4 | Neurotensin)
Affinity DataKi:  0.25nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2012
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50286868((1S,2S,4S)-2-{2-[(S)-2-({1-[6-Amino-2-(2,6-diamino...)
Affinity DataKi:  0.400nMAssay Description:Compound was tested in vitro for its binding affinity against Neurotensin Receptor after peripheral administrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50240845(2-{(S)-2-[2-({(S)-1-[(S)-2-((S)-2-Amino-5-guanidin...)
Affinity DataKi:  0.520nMAssay Description:Compound was tested in vitro for its binding affinity against Neurotensin Receptor after peripheral administrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50281794((S)-2-{(2S,3R)-2-[(S)-2-{2-[2-((S)-2-(S)-Amino-5-g...)
Affinity DataKi:  0.920nMAssay Description:Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50286866(2-{2-[(S)-2-({1-[(S)-6-Amino-2-((S)-2,6-diamino-he...)
Affinity DataKi:  1.10nMAssay Description:Compound was tested in vitro for its binding affinity against Neurotensin Receptor after peripheral administrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50281782((1S,4R)-2-{2-[2-[((S)-{(S)-1-[2-((S)-2-Amino-5-gua...)
Affinity DataKi:  2.10nMAssay Description:Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50286861((S)-2-{(S)-2-[(S)-2-({(R)-1-[6-Amino-2-(4-amino-bu...)
Affinity DataKi:  3.80nMAssay Description:Compound was tested in vitro for its binding affinity against Neurotensin Receptor after peripheral administrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50281786(2-{(S)-2-[2-({(S)-1-[(S)-2-((S)-2-Amino-5-guanidin...)
Affinity DataKi:  4.5nMAssay Description:Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50281783((S)-1-[(S)-2-((S)-2-Amino-5-guanidino-pentanoylami...)
Affinity DataKi:  10nMAssay Description:Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50563026(CHEMBL4748559)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]-neurotensin from NTS1 in mouse brain membrane incubated for 30 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50286863((S)-2-{(S)-2-[(S)-2-({(R)-1-[5-Amino-2-(3-amino-pr...)
Affinity DataKi:  17nMAssay Description:Compound was tested in vitro for its binding affinity against Neurotensin Receptor after peripheral administrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50286865((S)-2-{(S)-2-[(S)-2-({(R)-1-[(S)-6-Amino-2-((S)-2-...)
Affinity DataKi:  17nMAssay Description:Compound was tested in vitro for its binding affinity against Neurotensin Receptor after peripheral administrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50286867((S)-2-{(S)-2-[(S)-2-({(R)-1-[(S)-6-Amino-2-(6-amin...)
Affinity DataKi:  27nMAssay Description:Compound was tested in vitro for its binding affinity against Neurotensin Receptor after peripheral administrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50286869((S)-2-{(S)-2-[(S)-2-({(R)-1-[(S)-6-Amino-2-((S)-2,...)
Affinity DataKi:  31nMAssay Description:Compound was tested in vitro for its binding affinity against Neurotensin Receptor after peripheral administrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50286858((S)-2-{(S)-2-[(S)-2-{[(S)-1-((S)-2,6-Diamino-hexan...)
Affinity DataKi:  60nMAssay Description:Compound was tested in vitro for its binding affinity against Neurotensin Receptor after peripheral administrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50563028(CHEMBL4786197)
Affinity DataKi:  83nMAssay Description:Displacement of [3H]-neurotensin from NTS1 in mouse brain membrane incubated for 30 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50281780((2S,5S)-2-{2-[2-({(S)-1-[(S)-2-((S)-2-Amino-5-guan...)
Affinity DataKi:  110nMAssay Description:Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50281790(2-{(S)-2-[2-({(S)-1-[(S)-2-((S)-2-Amino-5-guanidin...)
Affinity DataKi:  200nMAssay Description:Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50563025(CHEMBL4750764)
Affinity DataKi:  410nMAssay Description:Displacement of [3H]-neurotensin from NTS1 in mouse brain membrane incubated for 30 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50286862((S)-2-{(S)-2-[(S)-2-({(R)-1-[(S)-6-Amino-2-((S)-2-...)
Affinity DataKi:  437nMAssay Description:Compound was tested in vitro for its binding affinity against Neurotensin Receptor after peripheral administrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50563027(CHEMBL4796388)
Affinity DataKi:  770nMAssay Description:Displacement of [3H]-neurotensin from NTS1 in mouse brain membrane incubated for 30 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50281789((S)-2-{2-[2-({(S)-1-[(S)-2-((S)-2-Amino-5-guanidin...)
Affinity DataKi:  3.90E+3nMAssay Description:Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetNeurotensin receptor type 1(Mouse)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50281792((S)-1-[(S)-2-((S)-2-Amino-5-guanidino-pentanoylami...)
Affinity DataKi:  1.20E+4nMAssay Description:Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article