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TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50458416(CHEMBL1230155)
Affinity DataKd:  9.00E+5nMAssay Description:Binding affinity to 15N-Gly/Cys/Ser/Trp-labeled human USP2a expressed in Escherichia coli BL21(DE3) assessed as change in chemical shift by NMR metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM442822(PR-619)
Affinity DataEC50:  7.20E+3nMAssay Description:Inhibition of USP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50636164(CHEMBL5556193)
Affinity DataIC50: 250nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50636166(CHEMBL5555634)
Affinity DataIC50: 800nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50636163(CHEMBL5561761)
Affinity DataIC50: 800nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50636157(CHEMBL5523555)
Affinity DataIC50: 890nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50608544(CHEMBL3392741)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human USP2 using Di-Ub IQF as substrate incubated for 15 mins by K63-2 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50608544(CHEMBL3392741)
Affinity DataIC50: 1.10E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50636162(CHEMBL5523445)
Affinity DataIC50: 1.30E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50636161(CHEMBL5560776)
Affinity DataIC50: 1.40E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50636151(CHEMBL5562321)
Affinity DataIC50: 1.50E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50636156(CHEMBL5542690)
Affinity DataIC50: 1.60E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50636145(CHEMBL5562765)
Affinity DataIC50: 3.20E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50636155(CHEMBL5532378)
Affinity DataIC50: 3.30E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50458422(CHEMBL4216958)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human USP2a (258 to 605 residues) expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate incubated for 30 mins measured at 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2 [258-605](Human)
Jagiellonian University

LigandPNGBDBM223973(LCAE)
Affinity DataIC50: 3.30E+3nMAssay Description:The assays were performed using Infinite 200 PRO - Tecan plate reader and 96-well, black Greiner microplates in a 100 ml reaction volume. The assays ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2017
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50636143(CHEMBL5560773)
Affinity DataIC50: 3.40E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50608544(CHEMBL3392741)
Affinity DataIC50: 3.60E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2 [258-605](Human)
Jagiellonian University

LigandPNGBDBM223976(LCAHA)
Affinity DataIC50: 3.70E+3nMAssay Description:The assays were performed using Infinite 200 PRO - Tecan plate reader and 96-well, black Greiner microplates in a 100 ml reaction volume. The assays ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2017
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50636149(CHEMBL5557100)
Affinity DataIC50: 3.80E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50591324(CHEMBL5185273)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of USP2 (unknown origin) using Ub-Rho measured after 0.5 to 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50636150(CHEMBL5557814)
Affinity DataIC50: 4.40E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50636158(CHEMBL5562196)
Affinity DataIC50: 4.60E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50591321(CHEMBL5172138)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of USP2 (unknown origin) using Ub-Rho measured after 0.5 to 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50636146(CHEMBL5559526)
Affinity DataIC50: 5.50E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50636152(CHEMBL5566850)
Affinity DataIC50: 5.50E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50375582(CHEMBL272041)
Affinity DataIC50: 5.80E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2 [258-605](Human)
Jagiellonian University

LigandPNGBDBM223973(LCAE)
Affinity DataIC50: 5.80E+3nMAssay Description:The assays were performed using Infinite 200 PRO - Tecan plate reader and 96-well, black Greiner microplates in a 100 ml reaction volume. The assays ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2017
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50636141(CHEMBL5565871)
Affinity DataIC50: 5.90E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50591322(CHEMBL5196686)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of USP2 (unknown origin) using Ub-Rho measured after 0.5 to 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50636142(CHEMBL5559268)
Affinity DataIC50: 6.40E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2 [258-605](Human)
Jagiellonian University

LigandPNGBDBM223972(LCACN)
Affinity DataIC50: 7.40E+3nMAssay Description:The assays were performed using Infinite 200 PRO - Tecan plate reader and 96-well, black Greiner microplates in a 100 ml reaction volume. The assays ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2017
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50458415(CHEMBL567508 | EN300-02284)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of human USP2a (258 to 605 residues) expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate incubated for 30 mins measured at 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50514116(CHEMBL4458718)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of USP2 (unknown origin) using Ub-AMC substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM223976(LCAHA)
Affinity DataIC50: 9.70E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2 [258-605](Human)
Jagiellonian University

LigandPNGBDBM223976(LCAHA)
Affinity DataIC50: 9.70E+3nMAssay Description:The assays were performed using Infinite 200 PRO - Tecan plate reader and 96-well, black Greiner microplates in a 100 ml reaction volume. The assays ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2017
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50591323(CHEMBL5173239)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of USP2 (unknown origin) using Ub-Rho measured after 0.5 to 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50538571(CHEMBL4635160)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human GST-tagged USP2 isoform 4 expressed in Escherichia coli assessed as cleavage of Ubiquitin-Rhodamine110-glycine to Ubiquitin and R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50636144(CHEMBL5562787)
Affinity DataIC50: 1.05E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50636154(CHEMBL5523454)
Affinity DataIC50: 1.33E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2 [258-605](Human)
Jagiellonian University

LigandPNGBDBM223972(LCACN)
Affinity DataIC50: 1.39E+4nMAssay Description:The assays were performed using Infinite 200 PRO - Tecan plate reader and 96-well, black Greiner microplates in a 100 ml reaction volume. The assays ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2017
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50636148(CHEMBL5560170)
Affinity DataIC50: 1.45E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50636160(CHEMBL5558678)
Affinity DataIC50: 1.54E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2 [258-605](Human)
Jagiellonian University

LigandPNGBDBM223975(LCANH2)
Affinity DataIC50: 1.67E+4nMAssay Description:The assays were performed using Infinite 200 PRO - Tecan plate reader and 96-well, black Greiner microplates in a 100 ml reaction volume. The assays ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2017
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50442907(CHEMBL3039433 | Acetyl Isogambogic Acid)
Affinity DataIC50: 1.82E+4nMpH: 7.5 T: 2°CAssay Description:Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM200235(Rifampicin | cid_5381226)
Affinity DataIC50: 2.12E+4nMpH: 7.5 T: 2°CAssay Description:Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM217379(CDDO-Me, 2)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of USP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2020
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50636159(CHEMBL5523517)
Affinity DataIC50: 2.23E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50612976(CHEMBL5266959)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human His-tagged USP2 (259 to 605 residues) using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50612975(CHEMBL5269490)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human His-tagged USP2 (259 to 605 residues) using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
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