Compile Data Set for Download or QSAR
Report error Found 472 of affinity data for UniProtKB/TrEMBL: O70528
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM82505(CAS_121881 | NSC_121881 | SB204070)
Affinity DataKi:  0.0100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM82505(CAS_121881 | NSC_121881 | SB204070)
Affinity DataKi:  0.0129nMAssay Description:Compound was tested for binding affinity against 5-HT4 receptor in guinea pig striata using [3H]GR-113808 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2020
Entry Details Article

Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM82505(CAS_121881 | NSC_121881 | SB204070)
Affinity DataKd:  0.0200nMAssay Description:Binding affinity to 5HT4 receptor in guinea pig distal colonMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50421360(SB-207058 | CHEMBL358119)
Affinity DataIC50: 0.0250nMAssay Description:Ability to antagonize 5-HT-evoked contractions mediated through 5-hydroxytryptamine 4 receptor activation in the guinea pig distal colon LMMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50421360(SB-207058 | CHEMBL358119)
Affinity DataIC50: 0.0251nMAssay Description:Ability to block 5-HT4 receptor mediated effect of 5-HT was assessed in the guinea-pig distal colon longitudinal muscle myenteric plexus preparation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article

Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM85020(GR-125487 | 5-Fluoro-2-methoxy-1H-indole-3-carboxy...)
Affinity DataKi:  0.0300nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM29525(GR 113808 | [3H] GR 113808 | CHEMBL518682 | 3H-GR1...)
Affinity DataKi:  0.0600nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM82505(CAS_121881 | NSC_121881 | SB204070)
Affinity DataKi:  0.0700nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM82505(CAS_121881 | NSC_121881 | SB204070)
Affinity DataIC50: 0.0794nMAssay Description:Ability to block 5-HT4 receptor mediated effect of 5-HT was assessed in the guinea-pig distal colon longitudinal muscle myenteric plexus preparation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article

Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM82505(CAS_121881 | NSC_121881 | SB204070)
Affinity DataIC50: 0.0800nMAssay Description:Ability to antagonize 5-HT-evoked contractions mediated through 5-hydroxytryptamine 4 receptor activation in the guinea pig distal colon LMMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM85027(1-(7-Chloro-8-amino-1,4-benzodioxane-5-yl)-3-[1-[3...)
Affinity DataKi:  0.100nMAssay Description:Compound was evaluated for binding affinity against 5-hydroxytryptamine 4 receptor using radioligand binding assay using [3H]GR as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2018
Entry Details

Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM85027(1-(7-Chloro-8-amino-1,4-benzodioxane-5-yl)-3-[1-[3...)
Affinity DataKi:  0.100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50421359(CHEMBL145075)
Affinity DataIC50: 0.100nMAssay Description:Ability to antagonize 5-HT-evoked contractions mediated through 5-hydroxytryptamine 4 receptor activation in the guinea pig distal colon LMMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM82505(CAS_121881 | NSC_121881 | SB204070)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of 5-HT-evoked 5-HT4 receptor-mediated contractions in the guinea pig distal colon longitudinal muscle myenteric plexus (LMMP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50422085(CHEMBL142490)
Affinity DataIC50: 0.100nMAssay Description:Ability to antagonize 5-HT-evoked contractions mediated through 5-hydroxytryptamine 4 receptor activation in the guinea pig distal colon LMMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50421359(CHEMBL145075)
Affinity DataIC50: 0.100nMAssay Description:Ability to block 5-HT4 receptor mediated effect of 5-HT was assessed in the guinea-pig distal colon longitudinal muscle myenteric plexus preparation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article

Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM29525(GR 113808 | [3H] GR 113808 | CHEMBL518682 | 3H-GR1...)
Affinity DataKi:  0.110nMAssay Description:Binding affinity against 5-hydroxytryptamine 4 receptor in guinea pig striatum using [3H]GR-113808 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50421362(CHEMBL143862)
Affinity DataIC50: 0.158nMAssay Description:Ability to block 5-HT4 receptor mediated effect of 5-HT was assessed in the guinea-pig distal colon longitudinal muscle myenteric plexus preparation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article

Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50421362(CHEMBL143862)
Affinity DataIC50: 0.160nMAssay Description:Ability to antagonize 5-HT-evoked contractions mediated through 5-hydroxytryptamine 4 receptor activation in the guinea pig distal colon LMMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50181844((1R,7aS)-hexahydro-1H-pyrrolizin-1-ylmethyl 4-amin...)
Affinity DataKi:  0.183nMAssay Description:Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50181840((1R,7aS)-hexahydro-1H-pyrrolizin-1-ylmethyl 1-Meth...)
Affinity DataKi:  0.183nMAssay Description:Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM85020(GR-125487 | 5-Fluoro-2-methoxy-1H-indole-3-carboxy...)
Affinity DataKi:  0.190nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50327858(CHEMBL114112 | SB207710 | 8-Amino-7-iodo-2,3-dihyd...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]GR113808 from 5HT4 receptor in guinea pig striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50327865((1-Butylpiperidin-4-yl)methyl 4-Amino-3-(2-fluoroe...)
Affinity DataKi:  0.215nMAssay Description:Displacement of [3H]GR113808 from 5HT4 receptor in guinea pig striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM29525(GR 113808 | [3H] GR 113808 | CHEMBL518682 | 3H-GR1...)
Affinity DataKi:  0.25nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM29525(GR 113808 | [3H] GR 113808 | CHEMBL518682 | 3H-GR1...)
Affinity DataKi:  0.25nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM29525(GR 113808 | [3H] GR 113808 | CHEMBL518682 | 3H-GR1...)
Affinity DataKi:  0.310nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM29525(GR 113808 | [3H] GR 113808 | CHEMBL518682 | 3H-GR1...)
Affinity DataKi:  0.310nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM29525(GR 113808 | [3H] GR 113808 | CHEMBL518682 | 3H-GR1...)
Affinity DataKi:  0.310nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50327863((1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3...)
Affinity DataKi:  0.334nMAssay Description:Displacement of [3H]GR113808 from 5HT4 receptor in guinea pig striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50327864((1-Butylpiperidin-4-yl)methyl 4-Amino-3-(fluoromet...)
Affinity DataKi:  0.334nMAssay Description:Displacement of [3H]GR113808 from 5HT4 receptor in guinea pig striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50469670(CHEMBL82976)
Affinity DataKi:  0.339nMAssay Description:Compound was tested for binding affinity against 5-HT4 receptor in guinea pig striata using [3H]GR-113808 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2020
Entry Details Article

Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50181845((1S,7aS)-1-{[(4-amino-5-chloro-2-methoxybenzoyl)am...)
Affinity DataKi:  0.350nMAssay Description:Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM85026(SB-207266 | N-(1-Butylpiperidine-4-ylmethyl)-1,2-(...)
Affinity DataKi:  0.390nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM29525(GR 113808 | [3H] GR 113808 | CHEMBL518682 | 3H-GR1...)
Affinity DataKi:  0.390nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50181837((1S,7aR)-hexahydro-1H-pyrrolizin-1-ylmethyl 1-meth...)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50327859((1-Butylpiperidin-4-yl)methyl 8-amino-7-cyano-2,3-...)
Affinity DataKi:  0.450nMAssay Description:Displacement of [3H]GR113808 from 5HT4 receptor in guinea pig striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50469669(CHEMBL84294)
Affinity DataKi:  0.468nMAssay Description:Compound was tested for binding affinity against 5-HT4 receptor in guinea pig striata using [3H]GR-113808 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2020
Entry Details Article

Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50469668(CHEMBL310667)
Affinity DataKi:  0.479nMAssay Description:Compound was tested for binding affinity against 5-HT4 receptor in guinea pig striata using [3H]GR-113808 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2020
Entry Details Article

Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50421361(CHEMBL143426)
Affinity DataIC50: 0.5nMAssay Description:Ability to antagonize 5-HT-evoked contractions mediated through 5-hydroxytryptamine 4 receptor activation in the guinea pig distal colon LMMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50421361(CHEMBL143426)
Affinity DataIC50: 0.501nMAssay Description:Ability to block 5-HT4 receptor mediated effect of 5-HT was assessed in the guinea-pig distal colon longitudinal muscle myenteric plexus preparation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article

Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50327860((1-Butylpiperidin-4-yl)methyl 7-chloro-8-(methylam...)
Affinity DataKi:  0.577nMAssay Description:Displacement of [3H]GR113808 from 5HT4 receptor in guinea pig striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50181842((1R,7aS)-hexahydro-1H-pyrrolizin-1-ylmethyl 5-Fluo...)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50327861((1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxyben...)
Affinity DataKi:  0.738nMAssay Description:Displacement of [3H]GR113808 from 5HT4 receptor in guinea pig striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM82273(CAS_167710-87-4 | RS 39604)
Affinity DataKi:  0.741nMAssay Description:Compound was tested for binding affinity against 5-HT4 receptor in guinea pig striata using [3H]GR-113808 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2020
Entry Details Article

Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM82273(CAS_167710-87-4 | RS 39604)
Affinity DataKi:  0.790nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM82273(CAS_167710-87-4 | RS 39604)
Affinity DataKi:  0.790nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50442803(CHEMBL2440453)
Affinity DataKi:  0.794nMAssay Description:Displacement of [125I]SB207710 from 5-HT4 receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50181841((1S,7aR)-hexahydro-1H-pyrrolizin-1-ylmethyl 1H-ind...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50469671(CHEMBL83755)
Affinity DataKi:  0.813nMAssay Description:Compound was tested for binding affinity against 5-HT4 receptor in guinea pig striata using [3H]GR-113808 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2020
Entry Details Article

Displayed 1 to 50 (of 472 total ) | Next | Last >>
Jump to: