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TargetProstaglandin G/H synthase 1(Bovine)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50247597(4,5-Bis(4-methoxyphenyl)-3H-1,2-dithiol-3-one | CH...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50247826(4,5-bis(4-methoxyphenyl)isothiazole | CHEMBL473946)
Affinity DataIC50: 3nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM13066({2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid |...)
Affinity DataIC50: 3nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Bovine)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of bovine COX1 assessed as inhibition of calcium ionophore A23187-induced 12-hydroxyheptadecatrienoic acid formation by reverse-phase HPLC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50247901(4-(4-Chlorophenyl)-5-p-tolyl-3H-1,2-dithiole-3-thi...)
Affinity DataIC50: 6nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50245432(4,5-Bis(4-methoxyphenyl)-1,2-selenazole | CHEMBL47...)
Affinity DataIC50: 6nMAssay Description:Inhibition of bovine COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225193(CHEMBL432463)
Affinity DataIC50: 8nMAssay Description:Inhibition of prostaglandin G/H synthase obtained from bovine seminal vesicles.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50247827(5-(4-methoxyphenyl)-4-p-tolylisothiazole | CHEMBL5...)
Affinity DataIC50: 10nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50245465(5-(4-Chlorophenyl)-4-(4-methoxyphenyl)-1,2-selenaz...)
Affinity DataIC50: 10nMAssay Description:Inhibition of bovine COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50247851(4-(4-Chlorophenyl)-5-(4-methoxyphenyl)isothiazole ...)
Affinity DataIC50: 20nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50247578(4-(4-Chlorophenyl)-5-p-tolyl-3H-1,2-dithiol-3-one ...)
Affinity DataIC50: 20nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50245466(4-(4-Chlorophenyl)-5-(4-methoxyphenyl)-1,2-selenaz...)
Affinity DataIC50: 20nMAssay Description:Inhibition of bovine COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50245433(5-(4-Methoxyphenyl)-4-p-tolyl-1,2-selenazole | CHE...)
Affinity DataIC50: 20nMAssay Description:Inhibition of bovine COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225114(CHEMBL28507)
Affinity DataIC50: 20nMAssay Description:Inhibition of prostaglandin G/H synthase obtained from bovine seminal vesicles.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225184(CHEMBL28976)
Affinity DataIC50: 20nMAssay Description:Inhibition of prostaglandin G/H synthase obtained from bovine seminal vesicles.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225190(CHEMBL28508)
Affinity DataIC50: 20nMAssay Description:Inhibition of prostaglandin G/H synthase obtained from bovine seminal vesicles.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50247902(4,5-bis(4-methoxyphenyl)-3H-1,2-dithiole-3-thione ...)
Affinity DataIC50: 30nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225186(CHEMBL281012)
Affinity DataIC50: 30nMAssay Description:Inhibition of prostaglandin G/H synthase obtained from bovine seminal vesicles.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50247847(5-(4-Chlorophenyl)-4-p-tolylisothiazole | CHEMBL52...)
Affinity DataIC50: 40nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225122(CHEMBL29047)
Affinity DataIC50: 40nMAssay Description:Inhibition of prostaglandin G/H synthase obtained from bovine seminal vesicles.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50245435(4-(4-Chlorophenyl)-5-p-tolyl-1,2-selenazole | CHEM...)
Affinity DataIC50: 50nMAssay Description:Inhibition of bovine COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225136(CHEMBL538408)
Affinity DataIC50: 50nMAssay Description:Inhibition of prostaglandin G/H synthase obtained from bovine seminal vesicles.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225141(CHEMBL418035)
Affinity DataIC50: 50nMAssay Description:Inhibition of prostaglandin G/H synthase obtained from bovine seminal vesicles.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50247850(5-(4-Chlorophenyl)-4-(4-methoxyphenyl)isothiazole ...)
Affinity DataIC50: 70nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225112(43-715 | Arthrex | Proquazone)
Affinity DataIC50: 70nMAssay Description:Inhibition of PG synthetase activity obtained from bovine seminal vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225123(CHEMBL28543)
Affinity DataIC50: 70nMAssay Description:Inhibition of prostaglandin G/H synthase obtained from bovine seminal vesicles.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225195(CHEMBL31313)
Affinity DataIC50: 70nMAssay Description:Inhibition of prostaglandin G/H synthase obtained from bovine seminal vesicles.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225126(CHEMBL283267)
Affinity DataIC50: 80nMAssay Description:Inhibition of prostaglandin G/H synthase obtained from bovine seminal vesicles.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225143(CHEBI:140536 | AHR-10282B | Bromday | Bromfenac So...)
Affinity DataIC50: 80nMAssay Description:Inhibition of prostaglandin G/H synthase obtained from bovine seminal vesicles.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50247849(4,5-Bis(4-chlorophenyl)isothiazole | CHEMBL491088)
Affinity DataIC50: 100nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225118(CHEMBL436147)
Affinity DataIC50: 100nMAssay Description:Inhibition of prostaglandin G/H synthase obtained from bovine seminal vesicles.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225121(CHEMBL286716)
Affinity DataIC50: 100nMAssay Description:Inhibition of prostaglandin G/H synthase obtained from bovine seminal vesicles.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225134(CHEMBL32037)
Affinity DataIC50: 100nMAssay Description:Inhibition of prostaglandin G/H synthase obtained from bovine seminal vesicles.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225176(CHEMBL29291)
Affinity DataIC50: 100nMAssay Description:Inhibition of prostaglandin G/H synthase obtained from bovine seminal vesicles.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50038649(ML-3000 | [2-(4-Chloro-phenyl)-6,6-dimethyl-1-phen...)
Affinity DataIC50: 150nMAssay Description:Inhibition of bovine COX1 assessed as inhibition of calcium ionophore A23187-induced 12-hydroxyheptadecatrienoic acid formation by reverse-phase HPLC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50247848(4-(4-Chlorophenyl)-5-p-tolylisothiazole | CHEMBL49...)
Affinity DataIC50: 200nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50247577(5-(4-Chlorophenyl)-4-p-tolyl-3H-1,2-dithiol-3-one ...)
Affinity DataIC50: 200nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50038649(ML-3000 | [2-(4-Chloro-phenyl)-6,6-dimethyl-1-phen...)
Affinity DataIC50: 200nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50245436(4,5-Bis(4-chlorophenyl)-1,2-selenazole | CHEMBL501...)
Affinity DataIC50: 200nMAssay Description:Inhibition of bovine COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50245434(5-(4-Chlorophenyl)-4-p-tolyl-1,2-selenazole | CHEM...)
Affinity DataIC50: 200nMAssay Description:Inhibition of bovine COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50224285(AHR-5850D | Amfenac Sodium | CHEBI:75918)
Affinity DataIC50: 200nMAssay Description:Evaluated for the inhibition of prostaglandin synthetase obtained from bovine seminal vesicles at the dose of 4.0 mg/kg (p.o.)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225110(CHEBI:75915 | Amfenac)
Affinity DataIC50: 200nMAssay Description:Inhibition of PG synthetase activity obtained from bovine seminal vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50224285(AHR-5850D | Amfenac Sodium | CHEBI:75918)
Affinity DataIC50: 200nMAssay Description:Inhibition of prostaglandin G/H synthase obtained from bovine seminal vesicles.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225140(CHEMBL28955)
Affinity DataIC50: 200nMAssay Description:Inhibition of prostaglandin G/H synthase obtained from bovine seminal vesicles.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225181(CHEMBL282828)
Affinity DataIC50: 200nMAssay Description:Inhibition of prostaglandin G/H synthase obtained from bovine seminal vesicles.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50022550(4-Hydroxy-2-(1-hydroxy-propyl)-8-trifluoromethyl-q...)
Affinity DataIC50: 200nMAssay Description:Inhibition of bovine Prostaglandin G/H synthase after oral administrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225117(CHEMBL28703)
Affinity DataIC50: 300nMAssay Description:Inhibition of prostaglandin G/H synthase obtained from bovine seminal vesicles.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225130(CHEMBL27620)
Affinity DataIC50: 300nMAssay Description:Inhibition of prostaglandin G/H synthase obtained from bovine seminal vesicles.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225135(CHEMBL284647)
Affinity DataIC50: 300nMAssay Description:Inhibition of prostaglandin G/H synthase obtained from bovine seminal vesicles.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225187(CHEMBL28700)
Affinity DataIC50: 300nMAssay Description:Inhibition of prostaglandin G/H synthase obtained from bovine seminal vesicles.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2018
Entry Details Article
PubMed
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