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Report error Found 34 of affinity data for UniProtKB/TrEMBL: O55239
TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566781(CHEMBL4867273)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566783(CHEMBL4859806)
Affinity DataIC50: 0.620nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566782(CHEMBL4857394)
Affinity DataIC50: 0.950nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566776(CHEMBL4847740)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566772(CHEMBL4878738)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566784(CHEMBL4872872)
Affinity DataIC50: 2nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566777(CHEMBL4848464)
Affinity DataIC50: 13nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566775(CHEMBL4856854)
Affinity DataIC50: 18nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566773(CHEMBL4853328)
Affinity DataIC50: 18nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50557606(CHEMBL4791213)
Affinity DataIC50: 21nMAssay Description:Inhibition of mouse NNMT using nicotinamide as substrate incubated for 2 hrs in presence of S-5'adenosyl-L-methionine by RapidFire Mass spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566771(CHEMBL4859039)
Affinity DataIC50: 23nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566759(CHEMBL4868588)
Affinity DataIC50: 25nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566785(CHEMBL4868364)
Affinity DataIC50: 40nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566770(CHEMBL4863816)
Affinity DataIC50: 58nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566780(CHEMBL4860372)
Affinity DataIC50: 73nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566765(CHEMBL4849636)
Affinity DataIC50: 96nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566766(CHEMBL4875414)
Affinity DataIC50: 188nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566774(CHEMBL4858283)
Affinity DataIC50: 214nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566760(CHEMBL4870987)
Affinity DataIC50: 217nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566786(CHEMBL4866114)
Affinity DataIC50: 243nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566764(CHEMBL4873940)
Affinity DataIC50: 253nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566779(CHEMBL4878905)
Affinity DataIC50: 263nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566762(CHEMBL4851654)
Affinity DataIC50: 277nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566778(CHEMBL4868547)
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566767(CHEMBL4856886)
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50455078(CHEMBL4218848)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of NNMT in mouse 3T3L1 cells assessed as reduction in MNA production after 24 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50455078(CHEMBL4218848)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of mouse NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50455095(CHEMBL4206972)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of mouse NNMT preincubated for 30 mins followed by substrate, cofactor addition and measured after 60 mins using nicotinamide as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50455095(CHEMBL4206972)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of endogenous mouse NNMT overexpressed in murine 3T3-L1 cells assessed incubated for 24 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566763(CHEMBL4869822)
Affinity DataIC50: 8.03E+3nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566761(CHEMBL4859787)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566787(CHEMBL4846940)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566769(CHEMBL4856096)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566768(CHEMBL4875995)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed