Compile Data Set for Download or QSAR
Report error Found 8381 of affinity data for UniProtKB/TrEMBL: O42275
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50292572(CHEMBL15910 | 3,3-dimethylbutan-2-yl methylphospho...)
Affinity DataKd:  610nMAssay Description:Binding affinity to electric eel AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50292572(CHEMBL15910 | 3,3-dimethylbutan-2-yl methylphospho...)
Affinity DataKd:  400nMAssay Description:Binding affinity to Electric eel AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50027343(CHEBI:75701 | ISOPROPYL METHYLPHOSPHONOFLUORIDATE)
Affinity DataKd:  2.20E+3nMAssay Description:Binding affinity to Electric eel AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50240416(diethyl 4-nitrophenyl phosphate | paraoxon | O,O-d...)
Affinity DataKd:  1.70E+5nMAssay Description:Binding affinity to Electric eel AChE using acetylthiocholine as substrate measured for 30 secs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50241991(CHEMBL4085438)
Affinity DataKd:  2.00E+3nMAssay Description:Binding affinity to Electric eel AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataKd:  16nMAssay Description:Binding affinity to electric eel AChE after 24 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50462577(CHEMBL4243833)
Affinity DataKd:  0nMAssay Description:Binding affinity to electric eel AChE after 24 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50462578(CHEMBL4239697)
Affinity DataKd:  0nMAssay Description:Binding affinity to electric eel AChE after 24 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50462580(CHEMBL4239268)
Affinity DataKd:  0nMAssay Description:Binding affinity to electric eel AChE after 24 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50044549(CHEMBL3314093)
Affinity DataKd:  0nMAssay Description:Binding affinity to electric eel AChE after 24 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50462581(CHEMBL4246013)
Affinity DataKd:  0nMAssay Description:Binding affinity to electric eel AChE after 24 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50044548(CHEMBL3314092)
Affinity DataKd:  0nMAssay Description:Binding affinity to electric eel AChE after 24 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50462576(CHEMBL4249808)
Affinity DataKd:  0nMAssay Description:Binding affinity to electric eel AChE after 24 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50462582(CHEMBL4250783)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to electric eel AChE after 24 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50149201(3,8-Diamino-6-phenyl-5-(6-{3-[2-(1,2,3,4-tetrahydr...)
Affinity DataKd:  0nMAssay Description:Binding affinity to electric eel AChE after 24 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50465496(CHEMBL4287206)
Affinity DataEC50:  1.21E+6nMAssay Description:Resurrection of methylphosphonate-aged electric eel AChE assessed as enzyme reactivation using acetylthiocholine as substrate at pH 9 after 1 day by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50465496(CHEMBL4287206)
Affinity DataEC50:  1.02E+6nMAssay Description:Resurrection of isopropyl phosphate-aged electric eel AChE assessed as enzyme reactivation using acetylthiocholine as substrate at pH 9 after 1 day b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50490821(2-Fluoroethyl 4-Nitrophenyl Ethylphosphonate | CHE...)
Affinity DataKoff:  1.43E+3s-1Assay Description:Inhibition of electric eel AChE by time-dependent inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50490822(2-Fluoroethyl 4-Nitrophenyl Methylphosphonate | CH...)
Affinity DataKoff:  417s-1Assay Description:Inhibition of electric eel AChE by time-dependent inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50490823(2-Bromoethyl 4-Nitrophenyl Methylphosphonate | CHE...)
Affinity DataKoff:  1.35E+3s-1Assay Description:Inhibition of electric eel AChE by concentration-dependent inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50490821(2-Fluoroethyl 4-Nitrophenyl Ethylphosphonate | CHE...)
Affinity DataKoff:  917s-1Assay Description:Inhibition of electric eel AChE by concentration-dependent inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50490824(CHEMBL2348369)
Affinity DataKoff:  200s-1Assay Description:Inhibition of electric eel AChE by time-dependent inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50240416(diethyl 4-nitrophenyl phosphate | paraoxon | O,O-d...)
Affinity DataKoff:  333s-1Assay Description:Inhibition of electric eel AChE by concentration-dependent inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50490822(2-Fluoroethyl 4-Nitrophenyl Methylphosphonate | CH...)
Affinity DataKoff:  983s-1Assay Description:Inhibition of electric eel AChE by concentration-dependent inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50490825(CHEMBL2348368)
Affinity DataKoff:  183s-1Assay Description:Inhibition of electric eel AChE by time-dependent inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50523387(CHEMBL4556281)
Affinity DataKd:  4.82E+3nMAssay Description:Displacement of propidium iodide from peripheral binding site of electric eel AChE assessed as dissociation constant at 8 to 56 uM by spectrofluorome...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50556952(CHEMBL4754487)
Affinity DataKd:  3.60nMAssay Description:Displacement of propidium iodide from PAS-region of electric eel AChE assessed as dissociation constant by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50560224(CHEMBL4751100)
Affinity DataKd:  2.03E+3nMAssay Description:Displacement of propidium iodide from PAS region of electric eel AChE by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50448131(CHEMBL3122167)
Affinity DataKd:  1.76E+3nMAssay Description:Displacement of propidium from electric eel AChE peripheral anionic site assessed as decrease in fluorescence intensity by spectrofluorometric analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50016936(CHEMBL3277093)
Affinity DataKoff:  18.3s-1Assay Description:Inhibition of electric eel AChE assessed as decrease in thiophenol formation using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50448130(CHEMBL3122168)
Affinity DataKd:  2.18E+3nMAssay Description:Displacement of propidium from electric eel AChE peripheral anionic site assessed as decrease in fluorescence intensity by spectrofluorometric analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50016937(CHEMBL3277094)
Affinity DataKoff:  0.430s-1Assay Description:Inhibition of electric eel AChE assessed as decrease in thiophenol formation using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50016938(CHEMBL3277095)
Affinity DataKoff:  13.3s-1Assay Description:Inhibition of electric eel AChE assessed as decrease in thiophenol formation using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50016935(CHEMBL3277092)
Affinity DataKoff:  68.3s-1Assay Description:Inhibition of electric eel AChE assessed as decrease in thiophenol formation using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50235363(CHEMBL4083174)
Affinity DataKd:  7.31E+3nMAssay Description:Displacement of propidium iodide from electric eel AChE by spectrofluorometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50016940(Ecothiopate Iodide | Phospholine Iodide | CHEBI:59...)
Affinity DataKoff:  4.33E+4s-1Assay Description:Inhibition of electric eel AChE assessed as decrease in thiophenol formation using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50016939(CHEMBL3277096)
Affinity DataKoff:  2.50E+4s-1Assay Description:Inhibition of electric eel AChE assessed as decrease in thiophenol formation using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50448132(CHEMBL3122150)
Affinity DataKd:  3.20E+3nMAssay Description:Displacement of propidium from electric eel AChE peripheral anionic site assessed as decrease in fluorescence intensity by spectrofluorometric analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50502681(CHEMBL4439521)
Affinity DataIC50: 0.0380nMAssay Description:Inhibition of electric eel AChE by Ellman's colorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50379273(CHEMBL1994202 | US9238626, (-)-Huprine Y HCl)
Affinity DataIC50: 0.0600nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and (+)-(Ib) was evaluated spectrophotometrically at 25° C. by the method of Ellman ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
Go to US Patent

TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50557533(CHEMBL4757683)
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM10592(7-chloro-15-methyl-10-azatetracyclo[11.3.1.0^{2,11...)
Affinity DataIC50: 0.0800nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and (+)-(Ib) was evaluated spectrophotometrically at 25° C. by the method of Ellman ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
Go to US Patent

TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50557532(CHEMBL4792421)
Affinity DataIC50: 0.0920nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50402577(CHEMBL2206129)
Affinity DataIC50: 0.110nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50402583(CHEMBL2206123)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM8963(N-[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]-...)
Affinity DataIC50: 0.170nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine chloride as substrate preincubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50595061(CHEMBL5209357)
Affinity DataIC50: 0.25nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine chloride as substrate preincubated for 20 mins followed by substrate addition by DTNB reagent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50435279(CHEMBL2393107)
Affinity DataIC50: 0.299nMAssay Description:Inhibition of electric eel AChE preincubated for 30 mins prior to horseradish peroxidase, H2O2 and DETAPAC addition measured for 20 mins under ROS co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50443517(CHEMBL3087899)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of electric eel AChE using acetylcholine as substrate preincubated for 15 mins prior to substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50502695(CHEMBL4535500)
Affinity DataIC50: 0.306nMAssay Description:Inhibition of electric eel AChE by Ellman's colorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
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