Compile Data Set for Download or QSAR
Report error Found 73 of affinity data for UniProtKB/TrEMBL: O35904
LigandPNGBDBM50462596(CHEMBL4242659)
Affinity DataIC50: 0.290nMAssay Description:Inhibition of PI3Kdelta in Balb/c mouse splenocytes-derived B cells assessed as reduction in anti-IgM antibody-stimulated B cell proliferation after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM50462587(CHEMBL4250271)
Affinity DataIC50: 0.410nMAssay Description:Inhibition of PI3Kdelta in Balb/c mouse splenocytes-derived B cells assessed as reduction in anti-IgM antibody-stimulated B cell proliferation after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM50462594(CHEMBL4249087)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of PI3Kdelta in Balb/c mouse splenocytes-derived B cells assessed as reduction in anti-IgM antibody-stimulated B cell proliferation after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM50462589(CHEMBL4247328)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of PI3Kdelta in Balb/c mouse splenocytes-derived B cells assessed as reduction in anti-IgM antibody-stimulated B cell proliferation after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM50462588(CHEMBL4248505)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of PI3Kdelta in Balb/c mouse splenocytes-derived B cells assessed as reduction in anti-IgM antibody-stimulated B cell proliferation after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM50380313(CHEMBL1234354 | US8633204, 286)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of mouse PI3Kdelta expressed in insect cells assessed as fluorescence polarization incubated for 30 mins by ATP competitive assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
LigandPNGBDBM50461379(CHEMBL4227156)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of PI3Kdelta in Balb/c mouse splenocytes-derived B cells assessed as reduction in anti-IgM antibody-stimulated B cell proliferation after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM50575900(CHEMBL4853960)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of mouse PI3KdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
LigandPNGBDBM50403096(CHEMBL2216895)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of PI3Kdelta in Balb/c mouse B cells assessed as inhibition of antiIgM-induced Akt phosphorylation at ser 473 residue preincubated for 45 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50461373(CHEMBL4228899)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of PI3Kdelta in Balb/c mouse splenocytes-derived B cells assessed as reduction in anti-IgM antibody-stimulated B cell proliferation after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM50462595(CHEMBL4250966)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of PI3Kdelta in Balb/c mouse splenocytes-derived B cells assessed as reduction in anti-IgM antibody-stimulated B cell proliferation after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM346183(US10202371, Example 13)
Affinity DataIC50: 3nMAssay Description:AlphaScreen (Amplified Luminescent Proximity Homogeneous Assay, ALPHA, Perkin Elmer) is a non-radioactive bead-based proximity assay technology to st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent

LigandPNGBDBM50232430(CHEMBL4061855 | US10214537, Example 262)
Affinity DataIC50: 4nMAssay Description:Inhibition of PI3Kdelta in mouse spleen assessed suppression of CD86More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM346184(US10202371, Example 14)
Affinity DataIC50: 4nMAssay Description:AlphaScreen (Amplified Luminescent Proximity Homogeneous Assay, ALPHA, Perkin Elmer) is a non-radioactive bead-based proximity assay technology to st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent

LigandPNGBDBM346182(US10202371, Example 12)
Affinity DataIC50: 4nMAssay Description:AlphaScreen (Amplified Luminescent Proximity Homogeneous Assay, ALPHA, Perkin Elmer) is a non-radioactive bead-based proximity assay technology to st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent

LigandPNGBDBM50557968(CHEMBL4754382)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of PI3Kdelta in Balb/c mouse B cells assessed as inhibition of antiIgM-induced Akt phosphorylation at ser 473 residue preincubated for 45 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50462590(CHEMBL4244862)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of PI3Kdelta in Balb/c mouse splenocytes-derived B cells assessed as reduction in anti-IgM antibody-stimulated B cell proliferation after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM50557972(CHEMBL4790186)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of PI3Kdelta in Balb/c mouse B cells assessed as inhibition of antiIgM-induced Akt phosphorylation at ser 473 residue preincubated for 45 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50557969(CHEMBL4763849)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of PI3Kdelta in Balb/c mouse B cells assessed as inhibition of antiIgM-induced Akt phosphorylation at ser 473 residue preincubated for 45 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50462593(CHEMBL4246031)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of PI3Kdelta in Balb/c mouse splenocytes-derived B cells assessed as reduction in anti-IgM antibody-stimulated B cell proliferation after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM50239718(US10214537, Example 639 | CHEMBL4064666)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of PI3Kdelta in mouse whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2019
Entry Details Article
PubMed
LigandPNGBDBM346173(US10202371, Example 3)
Affinity DataIC50: 6nMAssay Description:AlphaScreen (Amplified Luminescent Proximity Homogeneous Assay, ALPHA, Perkin Elmer) is a non-radioactive bead-based proximity assay technology to st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent

LigandPNGBDBM50462598(CHEMBL4245438)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of PI3Kdelta in Balb/c mouse splenocytes-derived B cells assessed as reduction in anti-IgM antibody-stimulated B cell proliferation after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM50403081(CHEMBL2216855)
Affinity DataIC50: 10nMAssay Description:Inhibition of PI3Kdelta-mediated AKT phosphorylation in mouse Raw 264.7 cells by immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM118299(US8653092, 67)
Affinity DataIC50: 10nMAssay Description:Inhibition of PI3Kdelta in anti-CD3/CD28 stimulated mouse CD4-positive T cells assessed as reduction in T cell differentiation to Th2 cells by measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50203699(CHEMBL3977066)
Affinity DataIC50: 11nMAssay Description:Inhibition of PI3Kdelta in Balb/c mouse in rat B cells assessed as reduction in anti-IgM induced proliferation measured over last 16 hrs of 88 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
LigandPNGBDBM346179(US10202371, Example 9)
Affinity DataIC50: 11nMAssay Description:AlphaScreen (Amplified Luminescent Proximity Homogeneous Assay, ALPHA, Perkin Elmer) is a non-radioactive bead-based proximity assay technology to st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent

LigandPNGBDBM346171((4S,5R)-3-(2′-Amino-2-morpholin-4-yl-4′...)
Affinity DataIC50: 11.3nMAssay Description:AlphaScreen (Amplified Luminescent Proximity Homogeneous Assay, ALPHA, Perkin Elmer) is a non-radioactive bead-based proximity assay technology to st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent

LigandPNGBDBM217352(GS-9820)
Affinity DataIC50: 12.7nMAssay Description:Biochemical in vitro lipid kinase assays were performed by the SelectScreen biochemical kinase assay service (Invitrogen Ltd.). A stock solution of G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2017
Entry Details Article
PubMed
LigandPNGBDBM118300(US8653092, 68)
Affinity DataIC50: 15nMAssay Description:Inhibition of PI3Kdelta in Balb/c mouse splenocytes assessed as reduction in anti-IgM stimulated CD86 expression pretreated for 1 hr followed by anti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2020
Entry Details Article
PubMed
LigandPNGBDBM346181(US10202371, Example 11)
Affinity DataIC50: 20nMAssay Description:AlphaScreen (Amplified Luminescent Proximity Homogeneous Assay, ALPHA, Perkin Elmer) is a non-radioactive bead-based proximity assay technology to st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent

LigandPNGBDBM50462591(CHEMBL4249694)
Affinity DataIC50: 20nMAssay Description:Inhibition of PI3Kdelta in Balb/c mouse splenocytes-derived B cells assessed as reduction in anti-IgM antibody-stimulated B cell proliferation after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM346180(US10202371, Example 10)
Affinity DataIC50: 22nMAssay Description:AlphaScreen (Amplified Luminescent Proximity Homogeneous Assay, ALPHA, Perkin Elmer) is a non-radioactive bead-based proximity assay technology to st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent

LigandPNGBDBM50533775(CHEMBL4588314)
Affinity DataIC50: 26nMAssay Description:Inhibition of PI3Kdelta in Balb/c mouse B cells assessed as reduction in anti-IgM induced CD86 expression preincubated for 1 hr followed by anti-IgM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
LigandPNGBDBM346178(US10202371, Example 8)
Affinity DataIC50: 28nMAssay Description:AlphaScreen (Amplified Luminescent Proximity Homogeneous Assay, ALPHA, Perkin Elmer) is a non-radioactive bead-based proximity assay technology to st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent

LigandPNGBDBM118299(US8653092, 67)
Affinity DataIC50: 33nMAssay Description:Inhibition of PI3Kdelta in mouse spleen cells assessed as reduction in cell proliferation by measuring [3H]thymidine incorporation by beta counting b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50203701(CHEMBL3944013)
Affinity DataIC50: 34nMAssay Description:Inhibition of PI3K-delta in mouse splenocytes assessed as inhibition anti-IgM induced CD86 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2018
Entry Details Article
PubMed
LigandPNGBDBM50203701(CHEMBL3944013)
Affinity DataIC50: 34nMAssay Description:Inhibition of PI3Kdelta in Balb/c mouse B cells assessed as reduction in anti-IgM induced CD86 expression preincubated for 1 hr followed by anti-IgM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
LigandPNGBDBM50203699(CHEMBL3977066)
Affinity DataIC50: 48nMAssay Description:Inhibition of PI3Kdelta in Balb/c mouse splenocytes assessed as reduction in anti-IgM stimulated CD86 expression pretreated for 1 hr followed by anti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2020
Entry Details Article
PubMed
LigandPNGBDBM118299(US8653092, 67)
Affinity DataIC50: 48nMAssay Description:Inhibition of PI3Kdelta in Balb/c mouse splenocytes assessed as reduction in anti-IgM stimulated CD86 expression pretreated for 1 hr followed by anti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM118299(US8653092, 67)
Affinity DataIC50: 48nMAssay Description:Inhibition of PI3Kdelta in Balb/c mouse splenocytes assessed as reduction in anti-IgM stimulated CD86 expression pretreated for 1 hr followed by anti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50203682(CHEMBL3947814)
Affinity DataIC50: 70nMAssay Description:Inhibition of PI3K-delta in mouse splenocytes assessed as inhibition anti-IgM induced CD86 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2018
Entry Details Article
PubMed
LigandPNGBDBM50203699(CHEMBL3977066)
Affinity DataIC50: 70nMAssay Description:Inhibition of PI3Kdelta in Balb/c mouse B cells assessed as reduction in anti-IgM induced CD86 expression preincubated for 1 hr followed by anti-IgM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
LigandPNGBDBM50203682(CHEMBL3947814)
Affinity DataIC50: 70nMAssay Description:Inhibition of PI3Kdelta in Balb/c mouse B cells assessed as reduction in anti-IgM induced CD86 expression preincubated for 1 hr followed by anti-IgM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
LigandPNGBDBM50203682(CHEMBL3947814)
Affinity DataIC50: 70nMAssay Description:Inhibition of PI3Kdelta in Balb/c mouse splenocytes assessed as reduction in anti-IgM stimulated CD86 expression pretreated for 1 hr followed by anti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2020
Entry Details Article
PubMed
LigandPNGBDBM50533778(CHEMBL4453497)
Affinity DataIC50: 74nMAssay Description:Inhibition of PI3Kdelta in Balb/c mouse B cells assessed as reduction in anti-IgM induced CD86 expression preincubated for 1 hr followed by anti-IgM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
LigandPNGBDBM50203699(CHEMBL3977066)
Affinity DataIC50: 74nMAssay Description:Inhibition of PI3K-delta in mouse splenocytes assessed as inhibition anti-IgM induced CD86 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2018
Entry Details Article
PubMed
LigandPNGBDBM50203696(CHEMBL3896413)
Affinity DataIC50: 82nMAssay Description:Inhibition of PI3K-delta in mouse splenocytes assessed as inhibition anti-IgM induced CD86 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2018
Entry Details Article
PubMed
LigandPNGBDBM118293(US8653092, 61)
Affinity DataIC50: 84nMAssay Description:Inhibition of PI3Kdelta in Balb/c mouse splenocytes assessed as reduction in anti-IgM stimulated CD86 expression pretreated for 1 hr followed by anti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2020
Entry Details Article
PubMed
LigandPNGBDBM50203685(CHEMBL3966263)
Affinity DataIC50: 85nMAssay Description:Inhibition of PI3K-delta in mouse splenocytes assessed as inhibition anti-IgM induced CD86 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2018
Entry Details Article
PubMed
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