Compile Data Set for Download or QSAR
Report error Found 12 of affinity data for UniProtKB/TrEMBL: O35235
TargetTumor necrosis factor ligand superfamily member 11(Mouse)
Shanghai Jiaotong University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50525150(CHEMBL4469489)
Affinity DataKd:  2.84E+5nMAssay Description:Binding affinity to mouse N-terminal His6-Trx-tagged RANKL ectodomain (157 to 316 residues) expressed in Escherichia coli BL21 (DE3) by isothermal ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetTumor necrosis factor ligand superfamily member 11(Mouse)
Shanghai Jiaotong University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50525146(CHEMBL4462272)
Affinity DataKd:  1.73E+4nMAssay Description:Binding affinity to mouse N-terminal His6-Trx-tagged RANKL ectodomain (157 to 316 residues) expressed in Escherichia coli BL21 (DE3) by isothermal ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetTumor necrosis factor ligand superfamily member 11(Mouse)
Shanghai Jiaotong University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50644349(CHEMBL5565740)
Affinity DataKd:  2.70nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTumor necrosis factor ligand superfamily member 11(Mouse)
Shanghai Jiaotong University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50128343(CHEMBL3629176)
Affinity DataIC50: 560nMAssay Description:Antiosteoclast activity in mouse BMM cells assessed as reduction of RANKL-induced osteoclasts differentiation by measuring TRAP positive multinucleat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetTumor necrosis factor ligand superfamily member 11(Mouse)
Shanghai Jiaotong University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50128344(CHEMBL3629177)
Affinity DataIC50: 580nMAssay Description:Antiosteoclast activity in mouse BMM cells assessed as reduction of RANKL-induced osteoclasts differentiation by measuring TRAP positive multinucleat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetTumor necrosis factor ligand superfamily member 11(Mouse)
Shanghai Jiaotong University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50128235(CHEMBL3628709)
Affinity DataIC50: 780nMAssay Description:Inhibition of M-CSF/sRANKL-induced mouse BMDM differentiation into osteoclast after 72 hrs by TRAP staining-based microscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetTumor necrosis factor ligand superfamily member 11(Mouse)
Shanghai Jiaotong University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50128342(CHEMBL3629175)
Affinity DataIC50: 1.31E+3nMAssay Description:Antiosteoclast activity in mouse BMM cells assessed as reduction of RANKL-induced osteoclasts differentiation by measuring TRAP positive multinucleat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetTumor necrosis factor ligand superfamily member 11(Mouse)
Shanghai Jiaotong University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50108929(CHEMBL3596956)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of recombinant mouse RANKL-induced TRAP activity in mouse RAW264.7 cells using 4-nitrophenyl phosphate as TRAP substrate preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2016
Entry Details Article
PubMed
TargetTumor necrosis factor ligand superfamily member 11(Mouse)
Shanghai Jiaotong University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50108928(CHEMBL3596954)
Affinity DataIC50: 4.29E+3nMAssay Description:Inhibition of recombinant mouse RANKL-induced TRAP activity in mouse RAW264.7 cells using 4-nitrophenyl phosphate as TRAP substrate preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2016
Entry Details Article
PubMed
TargetTumor necrosis factor ligand superfamily member 11(Mouse)
Shanghai Jiaotong University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50108927(CHEMBL3596952)
Affinity DataIC50: 4.31E+3nMAssay Description:Inhibition of recombinant mouse RANKL-induced TRAP activity in mouse RAW264.7 cells using 4-nitrophenyl phosphate as TRAP substrate preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2016
Entry Details Article
PubMed
TargetTumor necrosis factor ligand superfamily member 11(Mouse)
Shanghai Jiaotong University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50108930(CHEMBL3335186)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of recombinant mouse RANKL-induced TRAP activity in mouse RAW264.7 cells using 4-nitrophenyl phosphate as TRAP substrate preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2016
Entry Details Article
PubMed
TargetTumor necrosis factor ligand superfamily member 11(Mouse)
Shanghai Jiaotong University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 2.00E+4nMAssay Description:Antiosteoclast activity in mouse BMM cells assessed as reduction of RANKL-induced osteoclasts differentiation by measuring TRAP positive multinucleat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed