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Report error Found 17 of affinity data for UniProtKB/TrEMBL: O15528
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50261586(CHEMBL4099180)
Affinity DataIC50: 60nMAssay Description:Inhibition of human CYP27B1 expressed in Escherichia coli assessed as reduction in hydrolase activity incubated for 25 mins using Adx, AdR and 1,25(O...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50261589(CHEMBL4081152)
Affinity DataIC50: 95nMAssay Description:Inhibition of human CYP27B1 expressed in Escherichia coli assessed as reduction in hydrolase activity incubated for 25 mins using Adx, AdR and 1,25(O...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM151585(US8987315, Ketoconazole | US9180183, Ketoconazole ...)
Affinity DataIC50: 340nMAssay Description:Inhibition of human CYP27B1 expressed in Escherichia coli assessed as reduction in hydrolase activity incubated for 25 mins using Adx, AdR and 1,25(O...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50261588(CHEMBL4074768)
Affinity DataIC50: 410nMAssay Description:Inhibition of human CYP27B1 expressed in Escherichia coli assessed as reduction in hydrolase activity incubated for 25 mins using Adx, AdR and 1,25(O...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50214607(MK-24 | MK-24(S)-S(O)(NH)Ph | CHEMBL541423)
Affinity DataIC50: 554nMAssay Description:Inhibition of CYP27B1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50556038(CHEMBL389014)
Affinity DataIC50: 554nMAssay Description:Inhibition of CYP27B in human SW900 cells using 3H-(23,24)-25-(OH)D3 as substrate incubated for 5 hrs by HPLC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50370925(CHEMBL1627233)
Affinity DataIC50: 554nMAssay Description:Inhibition of human CYP27B hydroxylase expressed in SW900 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50261587(CHEMBL4104395)
Affinity DataIC50: 570nMAssay Description:Inhibition of human CYP27B1 expressed in Escherichia coli assessed as reduction in hydrolase activity incubated for 25 mins using Adx, AdR and 1,25(O...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50214606(Azole, 12 | CHEMBL253613 | 4'-chloro-biphenyl-4-ca...)
Affinity DataIC50: 616nMAssay Description:Inhibition of CYP27B1 in human keratinocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50322358(4'-Chloro-biphenyl-4-carboxylic acid((R)-2-imidazo...)
Affinity DataIC50: 616nMAssay Description:Inhibition of human CYP27B1 expressed in Escherichia coli assessed as reduction in hydrolase activity incubated for 25 mins using Adx, AdR and 1,25(O...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM8610(24F2-1,25(OH)D3 | Ketoconazole (k) | KTZ | 1-[4-(4...)
Affinity DataKi:  53nMAssay Description:Inhibition assay using CYP24A1 and CYP27B1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2013
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM92778(AB47)
Affinity DataKi:  68nMAssay Description:Inhibition assay using CYP24A1 and CYP27B1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2013
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM92780(VIMI)
Affinity DataKi:  90nMAssay Description:Inhibition assay using CYP24A1 and CYP27B1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2013
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM8610(24F2-1,25(OH)D3 | Ketoconazole (k) | KTZ | 1-[4-(4...)
Affinity DataKi:  92nMAssay Description:Inhibition assay using CYP24A1 and CYP27B1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2013
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM92779(TS17)
Affinity DataKi:  1.52E+3nMAssay Description:Inhibition assay using CYP24A1 and CYP27B1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2013
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM92776(24COOH-25(OH)D3)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition assay using CYP24A1 and CYP27B1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2013
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM92781(CPA1)
Affinity DataKi:  3.34E+3nMAssay Description:Inhibition assay using CYP24A1 and CYP27B1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2013
Entry Details Article
PubMed