Compile Data Set for Download or QSAR
Report error Found 197 of affinity data for UniProtKB/TrEMBL: O15303
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50293743(CHEMBL556667 | cid_836002 | N-(3-chlorophenyl)pico...)
Affinity DataEC50:  5.36E+3nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50074749(LY379268 | (1R,4R,5S,6R)-4-Amino-2-oxa-bicyclo[3.1...)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of forskolin stimulated cAMP production in RGT cells expressing recombinant human mGluR5aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50074750(LY-389795 | 4-Amino-2-thia-bicyclo[3.1.0]hexane-4,...)
Affinity DataEC50:  2.43E+3nMAssay Description:Inhibition of forskolin stimulated cAMP production in RGT cells expressing recombinant human mGluR6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50056272((2S,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dicarboxy...)
Affinity DataEC50:  2.99E+3nMAssay Description:Inhibition of forskolin stimulated cAMP production in RGT cells expressing recombinant human mGluR6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50074749(LY379268 | (1R,4R,5S,6R)-4-Amino-2-oxa-bicyclo[3.1...)
Affinity DataEC50:  401nMAssay Description:Inhibition of forskolin stimulated cAMP production in RGT cells expressing recombinant human mGluR6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50064463(CHEMBL3401177)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation at mGluR6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50064444(CHEMBL3401195)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation at mGluR6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50132507(CHEMBL3633943)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of mGlu6 receptor (unknown origin) relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50217030((1S,2S)-1-amino-2-phosphonomethylcyclopropane-carb...)
Affinity DataEC50:  3.41E+3nMAssay Description:Agonist activity at mGlu6 receptor expressed in HEK 293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50089516((1R,2S)-1-amino-2-(phosphonomethyl)cyclopropanecar...)
Affinity DataEC50:  1.11E+5nMAssay Description:Agonist activity at mGlu6 receptor expressed in HEK 293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50089518((1R,2R)-1-amino-2-(phosphonomethyl)cyclopropanecar...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at mGlu6 receptor expressed in HEK 293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50217031((1S,2R)-1-amino-2-phosphonomethylcyclopropane-carb...)
Affinity DataEC50:  1.95E+3nMAssay Description:Agonist activity at mGlu6 receptor expressed in HEK 293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50121643(CHEMBL3616847)
Affinity DataEC50:  3.45E+3nMAssay Description:Agonist activity at human recombinant mGlu6 receptor expressed in AV12 cells assessed as inhibition of forskolin-stimulated cAMP production after 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50145198(CHEMBL3765778)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of mGluR6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2017
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50169622(CHEMBL3805883)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of mGlu6 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2017
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50169621(CHEMBL3806176)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of mGlu6 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2017
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50169620(CHEMBL3804903)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of mGlu6 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2017
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50169619(CHEMBL3804910)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of mGlu6 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2017
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50169618(CHEMBL3806226)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of mGlu6 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2017
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50169689(CHEMBL3805203)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of mGlu6 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2017
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50169690(CHEMBL3806137)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of mGlu6 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2017
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50169693(CHEMBL3805139)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of mGlu6 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2017
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50145198(CHEMBL3765778)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of mGlu6 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2017
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50358179(CHEMBL1921961)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulator activity at human mGlu6 receptor at 10 uM by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50004051(CHEMBL285843 | 2-Amino-4-phosphono-butyric acid | ...)
Affinity DataEC50:  280nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | D-Glu | D-Glutamat...)
Affinity DataEC50:  4.90E+3nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50064246((1R,2S,4R,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  8.00E+5nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50064247((1S,2S,4S,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50064248((1S,2S,4S,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  5.30E+3nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM66976(SMR001230688 | trans-( )-ACPD monohydrate | cid_16...)
Affinity DataEC50:  8.20E+4nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50064245((1R,2S,4R,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM17662(CHEMBL276815 | 2-amino-3-(3-hydroxy-5-methyl-4-iso...)
Affinity DataEC50:  2.20E+5nMAssay Description:Agonist activity of the compound at Metabotropic Excitatory Amino acid Receptors Expressed in CHO cells. mGlu6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM31174(CHEMBL29757 | D-Aspartate | D-Aspartic Acid)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonistic activity at mGlu6 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM18125(L-Aspartic acid, 2 | L-Aspartate | CHEMBL274323 | ...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonistic activity at mGlu6 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM17657(L-Glutamic acid | L-Glu | (2S)-2-aminopentanedioic...)
Affinity DataEC50:  2.00E+4nMAssay Description:Agonistic activity at mGlu6 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50004852(CHEMBL280585 | AMAA | Amino-(3-hydroxy-5-methyl-is...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity of the compound at Metabotropic Excitatory Amino acid Receptors Expressed in CHO cells. mGlu6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | D-Glu | D-Glutamat...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonistic activity at mGlu6 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM85356(CAS_542-32-5 | (S)-2-Aminoadipic acid)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonistic activity at mGlu6 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50052551(2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-butyr...)
Affinity DataEC50:  8.20E+4nMAssay Description:Agonistic activity at mGlu6 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50052549(2-Amino-heptanedioic acid | CHEMBL111050)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonistic activity at mGlu6 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50052553((2S)-2-aminohexanedioic acid | L-2-aminoadipic aci...)
Affinity DataEC50:  1.40E+5nMAssay Description:Agonistic activity at mGlu6 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50052552(2-Amino-octanedioic acid | CHEMBL320957)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonistic activity at mGlu6 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50052555(2-Amino-5-(3-hydroxy-5-methyl-isoxazol-4-yl)-penta...)
Affinity DataEC50:  4.10E+5nMAssay Description:Agonistic activity at mGlu6 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50052554(2-Amino-6-(3-hydroxy-5-methyl-isoxazol-4-yl)-hexan...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonistic activity at mGlu6 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50026947(2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propi...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity of the compound at Metabotropic Excitatory Amino acid Receptors Expressed in CHO cells. mGlu6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50204257(CHEMBL3947221)
Affinity DataEC50: >1.25E+4nMAssay Description:Agonist activity at recombinant human mGlu6 receptor expressed in hamster AV12 cells co-expressing EAAT1 assessed as induction of forskolin-stimulate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2018
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50434128(CHEMBL2381646)
Affinity DataEC50:  1.18E+4nMAssay Description:Agonist activity at human mGlu6 receptor expressed in golden Syrian hamster AV12 cells coexpressing EAAT1 after 20 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50434129(CHEMBL2381647)
Affinity DataEC50:  9.37E+3nMAssay Description:Agonist activity at human mGlu6 receptor expressed in golden Syrian hamster AV12 cells coexpressing EAAT1 after 20 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50167034((1S,2S,4S,5R,6S)-2-Amino-4-methyl-bicyclo[3.1.0]he...)
Affinity DataEC50:  9.28E+3nMAssay Description:Agonist activity at human mGlu6 receptor expressed in golden Syrian hamster AV12 cells coexpressing EAAT1 after 20 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50167032((1S,2S,4R,5R,6S)-2-Amino-4-methyl-bicyclo[3.1.0]he...)
Affinity DataEC50:  7.54E+3nMAssay Description:Agonist activity at human mGlu6 receptor expressed in golden Syrian hamster AV12 cells coexpressing EAAT1 after 20 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
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