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Report error Found 310 of affinity data for UniProtKB/TrEMBL: O00748
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50409669(CHEMBL155514)
Affinity DataIC50: 0.178nMAssay Description:In vitro inhibition of carboxylesterase in human liver microsomes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50409660(CHEMBL155513)
Affinity DataIC50: 3.39nMAssay Description:In vitro inhibition of carboxylesterase in human liver microsomes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50570553(CHEMBL4854298)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant CES2 expressed in mouse NSO cells using 4-NPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50570549(CHEMBL4853742)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human recombinant CES2 expressed in mouse NSO cells using 4-NPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50409672(CHEMBL153080)
Affinity DataIC50: 5.5nMAssay Description:In vitro inhibition of carboxylesterase in human liver microsomes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of human recombinant carboxylesterase 2 after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371971(CHEMBL440542)
Affinity DataIC50: 6.92nMAssay Description:In vitro inhibition of carboxylesterase in human liver microsomes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371961(CHEMBL270373)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of human recombinant carboxylesterase 2 after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371970(CHEMBL89506)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human recombinant carboxylesterase 2 after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50570554(CHEMBL4858186)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of human recombinant CES2 expressed in mouse NSO cells using 4-NPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50643043(CHEMBL5573291)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50643044(CHEMBL5574138)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50643045(CHEMBL5568952)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371961(CHEMBL270373)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant carboxylesterase 2 after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50570555(CHEMBL4868014)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant CES2 expressed in mouse NSO cells using 4-NPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50570561(CHEMBL4855838)
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant CES2 expressed in mouse NSO cells using 4-NPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50643051(CHEMBL5567105)
Affinity DataIC50: 18nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50154561(CHEMBL3774603)
Affinity DataIC50: 20nMAssay Description:Inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2017
Entry Details Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371959(CHEMBL86668)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant carboxylesterase 2 after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371964(CHEMBL273139)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant carboxylesterase 2 after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50570551(CHEMBL4853637)
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant CES2 expressed in mouse NSO cells using 4-NPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371964(CHEMBL273139)
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant carboxylesterase 2 after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50409657(CHEMBL153015)
Affinity DataIC50: 32.4nMAssay Description:In vitro inhibition of carboxylesterase in human liver microsomes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371959(CHEMBL86668)
Affinity DataIC50: 36nMAssay Description:Inhibition of human recombinant carboxylesterase 2 after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM22722(1,2-diphenylethane-1,2-dione | Diphenylethane-1,2-...)
Affinity DataIC50: 38nMAssay Description:Inhibition of human recombinant carboxylesterase 2 after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50643046(CHEMBL5593400)
Affinity DataIC50: 38nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50643053(CHEMBL5567018)
Affinity DataIC50: 43nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM22722(1,2-diphenylethane-1,2-dione | Diphenylethane-1,2-...)
Affinity DataIC50: 44nMAssay Description:Inhibition of human recombinant carboxylesterase 2 after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50371960(CHEMBL155621)
Affinity DataIC50: 46.8nMAssay Description:In vitro inhibition of carboxylesterase in human liver microsomes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50409670(CHEMBL421992)
Affinity DataIC50: 47.9nMAssay Description:In vitro inhibition of carboxylesterase in human liver microsomes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50570558(CHEMBL4849436)
Affinity DataIC50: 48nMAssay Description:Inhibition of human recombinant CES2 expressed in mouse NSO cells using 4-NPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50552232(CHEMBL4776624)
Affinity DataIC50: 52nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50643039(CHEMBL5574747)
Affinity DataIC50: 59nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50643054(CHEMBL5569141)
Affinity DataIC50: 61nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50643047(CHEMBL5575498)
Affinity DataIC50: 66nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50643041(CHEMBL5572109)
Affinity DataIC50: 68nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50643040(CHEMBL5569484)
Affinity DataIC50: 70nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50570552(CHEMBL4855755)
Affinity DataIC50: 71nMAssay Description:Inhibition of human recombinant CES2 expressed in mouse NSO cells using 4-NPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50570550(CHEMBL4849361)
Affinity DataIC50: 72nMAssay Description:Inhibition of human recombinant CES2 expressed in mouse NSO cells using 4-NPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50409658(CHEMBL153177)
Affinity DataIC50: 100nMAssay Description:In vitro inhibition of carboxylesterase in human liver microsomes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50643049(CHEMBL5565903)
Affinity DataIC50: 126nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50571105(CHEMBL4851375)
Affinity DataIC50: 130nMAssay Description:Inhibition of CES2 in human liver microsomes assessed as reduction in substrate hydrolysis using fluorescein diacetate as substrate preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50643042(CHEMBL5573951)
Affinity DataIC50: 172nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50643055(CHEMBL5572084)
Affinity DataIC50: 177nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50643050(CHEMBL5572424)
Affinity DataIC50: 178nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50643052(CHEMBL4095302)
Affinity DataIC50: 189nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50570559(CHEMBL4868687)
Affinity DataIC50: 193nMAssay Description:Inhibition of human recombinant CES2 expressed in mouse NSO cells using 4-NPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50643048(CHEMBL5569676)
Affinity DataIC50: 193nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50570566(CHEMBL4849604)
Affinity DataIC50: 230nMAssay Description:Inhibition of human recombinant CES2 expressed in mouse NSO cells using 4-NPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCocaine esterase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50505364(CHEMBL4460898)
Affinity DataIC50: 260nMAssay Description:Inhibition of CES2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
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