Compile Data Set for Download or QSAR
Report error Found 3438 of affinity data for UniProtKB/TrEMBL: O00519
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339891((S)-1-ethyl-3-(1-(4-(thiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataEC50:  350nMAssay Description:Inhibition of FAAH in human T84 cell assessed as conversion of [3H]AEA to [3H]ethanolamine by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339871((S)-3-(1-(4-(5-chlorothiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataEC50:  3nMAssay Description:Inhibition of FAAH in human T84 cell assessed as conversion of [3H]AEA to [3H]ethanolamine by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339872((S)-3-(1-(4-(5-chlorothiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataEC50:  2nMAssay Description:Inhibition of FAAH in human T84 cell assessed as conversion of [3H]AEA to [3H]ethanolamine by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339886((S)-3-(1-(2-amino-6-(4-fluorophenyl)pyrimidin-4-yl...)
Affinity DataEC50:  20nMAssay Description:Inhibition of FAAH in human T84 cell assessed as conversion of [3H]AEA to [3H]ethanolamine by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50434313(CHEMBL2386571)
Affinity DataKd:  0.800nMAssay Description:Binding affinity to FAAH in human cortical homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50166881(CHEMBL3798535)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50166892(CHEMBL3797772)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50166880(CHEMBL3798487)
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50447747(CHEMBL3113272)
Affinity DataIC50: 0.0250nMAssay Description:Apparent inhibition of human FAAH expressed in CHOK1 cells using AMCAA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50166868(CHEMBL3797635)
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50166873(CHEMBL3800456)
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50166871(CHEMBL3797841)
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50166866(CHEMBL3798156)
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50447748(CHEMBL3113271)
Affinity DataIC50: 0.0720nMAssay Description:Apparent inhibition of human FAAH expressed in CHOK1 cells using AMCAA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50166869(CHEMBL3799744)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50447745(CHEMBL3113274)
Affinity DataIC50: 0.0800nMAssay Description:Apparent inhibition of human FAAH expressed in CHOK1 cells using AMCAA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50166890(CHEMBL3797809)
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50350535(CHEMBL1812722)
Affinity DataIC50: 0.0930nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50161525(1-(oxazolo[4,5-b]pyridin-2-yl)-9-phenylnonan-1-one...)
Affinity DataIC50: 0.100nMAssay Description:Inhibitory concentration of fatty acid amide hydrolase using FP-Rh radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50132714((5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenesulfonyl f...)
Affinity DataIC50: 0.100nMAssay Description:Irreversible inhibition of fatty acid amide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50166867(CHEMBL3798476)
Affinity DataIC50: 0.140nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50309725(nicotinaldehyde O-4-(undecyloxy)phenylcarbamoyl ox...)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50166910(CHEMBL3798355)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50250852(CHEMBL4078217)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of human recombinant FAAH using arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2019
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50166878(CHEMBL3800599)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50166891(CHEMBL3799008)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50166911(CHEMBL3799516)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50309712(4-fluorobenzaldehyde O-4-(nonyloxy)phenylcarbamoyl...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM26739(URB 597 | URB597 | CHEMBL184238 | 3-(3-carbamoylph...)
Affinity DataIC50: 0.240nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50309701(benzaldehyde O-4-(nonyloxy)phenylcarbamoyl oxime |...)
Affinity DataIC50: 0.25nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50309713(4-fluorobenzaldehyde O-4-(decyloxy)phenylcarbamoyl...)
Affinity DataIC50: 0.25nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50309711(4-fluorobenzaldehyde O-4-(octyloxy)phenylcarbamoyl...)
Affinity DataIC50: 0.270nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50161520(1-(oxazolo[4,5-b]pyridin-2-yl)-8-phenyloctan-1-one...)
Affinity DataIC50: 0.300nMAssay Description:Inhibitory concentration of fatty acid amide hydrolase using FP-Rh radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM23316(7-phenyl-1-{pyrido[2,3-d][1,3]oxazol-2-yl}heptan-1...)
Affinity DataIC50: 0.300nMAssay Description:Inhibitory concentration of fatty acid amide hydrolase using FP-Rh radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM23316(7-phenyl-1-{pyrido[2,3-d][1,3]oxazol-2-yl}heptan-1...)
Affinity DataIC50: 0.300nMAssay Description:Inhibitory concentration against Fatty-acid amide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50434318(CHEMBL2386566)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human FAAH expressed in CHO cell lysates assessed as arachidonyl-7-amino-4-methylcoumarin amide hydrolysis to 7-amino 4-methyl coumarin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50132713(Methyl arachidonoyl fluorophophonate | methyl -ico...)
Affinity DataIC50: 0.330nMAssay Description:Inhibition of human FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50132713(Methyl arachidonoyl fluorophophonate | methyl -ico...)
Affinity DataIC50: 0.331nMAssay Description:Inhibition of human recombinant FAAH-maltose binding proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50309702(benzaldehyde O-4-(decyloxy)phenylcarbamoyl oxime |...)
Affinity DataIC50: 0.350nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50309724(nicotinaldehyde O-4-(decyloxy)phenylcarbamoyl oxim...)
Affinity DataIC50: 0.350nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50309726(nicotinaldehyde O-4-(dodecyloxy)phenylcarbamoyl ox...)
Affinity DataIC50: 0.350nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50166870(CHEMBL3797226)
Affinity DataIC50: 0.360nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM393394(US9963444, Example 95)
Affinity DataIC50: 0.360nMAssay Description:Inhibition of recombinant human FAAH expressed in Escherichia coli using fluorogenic AAMCA as substrate by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM23120(CHEMBL177577 | 7-phenyl-1-[5-(pyridin-2-yl)-1,3-ox...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50309714(4-fluorobenzaldehyde O-4-(undecyloxy)phenylcarbamo...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50275260(1-(oxazol-2-yl)-4-(1-(3-phenoxybenzyl)piperidin-4-...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50166875(CHEMBL3797377)
Affinity DataIC50: 0.410nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50309700(benzaldehyde O-4-(octyloxy)phenylcarbamoyl oxime |...)
Affinity DataIC50: 0.430nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50426652(CHEMBL2326178)
Affinity DataIC50: 0.430nMAssay Description:Apparent inhibition of human FAAH expressed in CHO-K1 cells using ethanolamine 1-3[H] as substrate after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50309703(benzaldehyde O-4-(undecyloxy)phenylcarbamoyl oxime...)
Affinity DataIC50: 0.450nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
Displayed 1 to 50 (of 3438 total ) | Next | Last >>
Jump to: