Compile Data Set for Download or QSAR
Report error Found 52 of affinity data for UniProtKB/TrEMBL: K9N7C7
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50384265(CHEMBL2030452)
Affinity DataKd:  7.60E+3nMAssay Description:Binding affinity to MERS-CoV papain-like protease by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM513874(bioRxiv20220126.477782, Screening Hit 2 | bioRxiv2...)
Affinity DataEC50:  1.40E+3nMAssay Description:Antiviral activity against SARS-CoV-2, SARS-CoV, MERS-CoV and HCoV-229E was assessed by monitoring cell viability; that against HCoV-OC43 was assesse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details

TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM97231(2-[(E)-2-(4-morpholin-4-ylphenyl)ethenyl]quinoline...)
Affinity DataKd:  7.60E+3nMAssay Description:Binding affinity to MERS-CoV papain-like protease by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50192743(CHEBI:50205 | 3,4-Dihydroxybenzaldehyde | Protocat...)
Affinity DataKd:  2.20E+5nMAssay Description:Binding affinity to MERS-CoV papain-like protease by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50523945(CHEMBL4475926)
Affinity DataKd:  7.60E+3nMAssay Description:Binding affinity to MERS-CoV papain-like protease by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50523950(CHEMBL1368663)
Affinity DataKd:  7.60E+3nMAssay Description:Binding affinity to MERS-CoV papain-like protease by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50103596(CHEBI:9334 | Azulfidine | Azulfidine EN | Azulfidi...)
Affinity DataKd:  7.60E+3nMAssay Description:Binding affinity to MERS-CoV papain-like protease by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50523946(ONO-1078)
Affinity DataKd:  1.41E+4nMAssay Description:Binding affinity to MERS-CoV papain-like protease by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50523944(CHEMBL4544405)
Affinity DataKd:  7.60E+3nMAssay Description:Binding affinity to MERS-CoV papain-like protease by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM496960(cmdc.202100576, 23c)
Affinity DataIC50: 1nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM496959(cmdc.202100576, 23b)
Affinity DataIC50: 1nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM496962(cmdc.202100576, 23e)
Affinity DataIC50: 2nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM496961(cmdc.202100576, 23d)
Affinity DataIC50: 2nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM496963(cmdc.202100576, 23f)
Affinity DataIC50: 5nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM476929(SARS-CoV-2 3CLpro Inhibitors 3b | SARS-CoV-2 3CLpr...)
Affinity DataIC50: 49nMAssay Description:Cloning and Expression of the 3CL Protease of SARS-CoV-2 and FRET Enzyme Assays. The codon-optimized cDNA of full length of 3CLpro of SARS-CoV-2 (Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM476928(SARS-CoV-2 3CLpro Inhibitors 2b | SARS-CoV-2 3CLpr...)
Affinity DataIC50: 52nMAssay Description:Cloning and Expression of the 3CL Protease of SARS-CoV-2 and FRET Enzyme Assays. The codon-optimized cDNA of full length of 3CLpro of SARS-CoV-2 (Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM476949(SARS-CoV-2 3CLpro Inhibitors 3l | SARS-CoV-2 3CLpr...)
Affinity DataIC50: 53nMAssay Description:Cloning and Expression of the 3CL Protease of SARS-CoV-2 and FRET Enzyme Assays. The codon-optimized cDNA of full length of 3CLpro of SARS-CoV-2 (Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM476948(SARS-CoV-2 3CLpro Inhibitors 2l | SARS-CoV-2 3CLpr...)
Affinity DataIC50: 55nMAssay Description:Cloning and Expression of the 3CL Protease of SARS-CoV-2 and FRET Enzyme Assays. The codon-optimized cDNA of full length of 3CLpro of SARS-CoV-2 (Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM476939(SARS-CoV-2 3CLpro Inhibitors 3f)
Affinity DataIC50: 58nMAssay Description:Cloning and Expression of the 3CL Protease of SARS-CoV-2 and FRET Enzyme Assays. The codon-optimized cDNA of full length of 3CLpro of SARS-CoV-2 (Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM476938(SARS-CoV-2 3CLpro Inhibitors 2f)
Affinity DataIC50: 63nMAssay Description:Cloning and Expression of the 3CL Protease of SARS-CoV-2 and FRET Enzyme Assays. The codon-optimized cDNA of full length of 3CLpro of SARS-CoV-2 (Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM496949(cmdc.202100576, 20b | GC868 | cmdc.202100576, 20e)
Affinity DataIC50: 300nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50458469(CHEMBL4208240)
Affinity DataIC50: 400nMAssay Description:Inhibition of Middle East respiratory syndrome-related coronavirus 3CL protease using Dabcyl-KTSAVLQ/SGFRKME-Edans as substrate incubated for 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM496950(cmdc.202100576, 20c | GC867)
Affinity DataIC50: 500nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50458471(CHEMBL4204431)
Affinity DataIC50: 500nMAssay Description:Inhibition of Middle East respiratory syndrome-related coronavirus 3CL protease using Dabcyl-KTSAVLQ/SGFRKME-Edans as substrate incubated for 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM496949(cmdc.202100576, 20b | GC868 | cmdc.202100576, 20e)
Affinity DataIC50: 600nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM496951(cmdc.202100576, 20d | GC861)
Affinity DataIC50: 600nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50458472(CHEMBL4217568)
Affinity DataIC50: 600nMAssay Description:Inhibition of Middle East respiratory syndrome-related coronavirus 3CL protease using Dabcyl-KTSAVLQ/SGFRKME-Edans as substrate incubated for 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50458462(CHEMBL4214066)
Affinity DataIC50: 600nMAssay Description:Inhibition of Middle East respiratory syndrome-related coronavirus 3CL protease using Dabcyl-KTSAVLQ/SGFRKME-Edans as substrate incubated for 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50458463(CHEMBL4213159)
Affinity DataIC50: 600nMAssay Description:Inhibition of Middle East respiratory syndrome-related coronavirus 3CL protease using Dabcyl-KTSAVLQ/SGFRKME-Edans as substrate incubated for 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM496953(cmdc.202100576, 20f | GC833)
Affinity DataIC50: 700nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50458465(CHEMBL4203883)
Affinity DataIC50: 700nMAssay Description:Inhibition of Middle East respiratory syndrome-related coronavirus 3CL protease using Dabcyl-KTSAVLQ/SGFRKME-Edans as substrate incubated for 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50458470(CHEMBL4209146)
Affinity DataIC50: 700nMAssay Description:Inhibition of Middle East respiratory syndrome-related coronavirus 3CL protease using Dabcyl-KTSAVLQ/SGFRKME-Edans as substrate incubated for 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50458473(CHEMBL4214471)
Affinity DataIC50: 700nMAssay Description:Inhibition of Middle East respiratory syndrome-related coronavirus 3CL protease using Dabcyl-KTSAVLQ/SGFRKME-Edans as substrate incubated for 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50458464(CHEMBL4202812)
Affinity DataIC50: 800nMAssay Description:Inhibition of Middle East respiratory syndrome-related coronavirus 3CL protease using Dabcyl-KTSAVLQ/SGFRKME-Edans as substrate incubated for 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50458466(CHEMBL4208764)
Affinity DataIC50: 900nMAssay Description:Inhibition of Middle East respiratory syndrome-related coronavirus 3CL protease using Dabcyl-KTSAVLQ/SGFRKME-Edans as substrate incubated for 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM429497(med.21724, Compound 170)
Affinity DataIC50: 6.00E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50458467(CHEMBL4212620)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of Middle East respiratory syndrome-related coronavirus 3CL protease using Dabcyl-KTSAVLQ/SGFRKME-Edans as substrate incubated for 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50458468(CHEMBL4216101)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of Middle East respiratory syndrome-related coronavirus 3CL protease using Dabcyl-KTSAVLQ/SGFRKME-Edans as substrate incubated for 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50058655(1,1',1'',1'''-[disulfanediylbis(carbonothioylnitri...)
Affinity DataIC50: 1.46E+4nMAssay Description:Inhibition of recombinant MERS-CoV PL protease using Ub-AFC incubated for 3 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50523945(CHEMBL4475926)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of MERS-CoV papain-like protease using Z-Arg-Leu-Arg-Gly-Gly-AMC as substrate preincubated for 5 mins followed by substrate addition and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM429499(med.21724, Compound 172)
Affinity DataIC50: 2.44E+4nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50523946(ONO-1078)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of MERS-CoV papain-like protease using Z-Arg-Leu-Arg-Gly-Gly-AMC as substrate preincubated for 5 mins followed by substrate addition and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM429498(med.21724, Compound 171)
Affinity DataIC50: 2.69E+4nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50121025(broussochalcone A | (E)-1-[2,4-Dihydroxy-5-(3-meth...)
Affinity DataIC50: 4.21E+4nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50001908(CHEMBL165012 | 1-(4-Nitro-phenyl)-piperazine)
Affinity DataIC50: 7.16E+4nMAssay Description:Inhibition of MERS-CoV papain-like protease using Z-Arg-Leu-Arg-Gly-Gly-AMC as substrate preincubated for 5 mins followed by substrate addition and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM429503(med.21724, Compound 176)
Affinity DataIC50: 1.13E+5nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50523947(CHEMBL4447423)
Affinity DataIC50: 1.37E+5nMAssay Description:Inhibition of MERS-CoV papain-like protease using Z-Arg-Leu-Arg-Gly-Gly-AMC as substrate preincubated for 5 mins followed by substrate addition and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50523948(CHEBI:78878 | CHEMBL1743207)
Affinity DataIC50: 1.41E+5nMAssay Description:Inhibition of MERS-CoV papain-like protease using Z-Arg-Leu-Arg-Gly-Gly-AMC as substrate preincubated for 5 mins followed by substrate addition and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50523949(CHEBI:16318 | 4-Nitrocatechol)
Affinity DataIC50: 1.45E+5nMAssay Description:Inhibition of MERS-CoV papain-like protease using Z-Arg-Leu-Arg-Gly-Gly-AMC as substrate preincubated for 5 mins followed by substrate addition and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50192743(CHEBI:50205 | 3,4-Dihydroxybenzaldehyde | Protocat...)
Affinity DataIC50: 2.39E+5nMAssay Description:Inhibition of MERS-CoV papain-like protease using Z-Arg-Leu-Arg-Gly-Gly-AMC as substrate preincubated for 5 mins followed by substrate addition and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
Displayed 1 to 50 (of 52 total ) | Next | Last >>
Jump to: