Compile Data Set for Download or QSAR
Report error Found 3 of affinity data for UniProtKB/TrEMBL: G3IAK4
TargetBeta-secretase 1(Chinese hamster)
University of Coimbra

Curated by ChEMBL
LigandPNGBDBM50023040(CHEMBL2272783)
Affinity DataEC50:  7.30E+4nMAssay Description:Inhibition of BACE-1 in CHO cells expressing wild-type APP assessed as reduction in amyloid beta-40 production after 6 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetBeta-secretase 1(Chinese hamster)
University of Coimbra

Curated by ChEMBL
LigandPNGBDBM116257(US8637508, 34 | US10035794, Example 34 | US1068328...)
Affinity DataIC50: 3nMAssay Description:Inhibition of BACE1 in CHO cells expressing human APP assessed as reduction in amyloidbeta (1 to 40 residues) level incubated for 24 hrs by immunoass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-secretase 1(Chinese hamster)
University of Coimbra

Curated by ChEMBL
LigandPNGBDBM186048(US9163011, 2)
Affinity DataIC50: 8nMAssay Description:Inhibition of BACE1 in CHO cells expressing human APP assessed as reduction in amyloidbeta (1 to 40 residues) level incubated for 24 hrs by immunoass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed