Compile Data Set for Download or QSAR
Report error Found 61 of affinity data for UniProtKB/TrEMBL: F5BCZ9
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50503152(CHEMBL4452216)
Affinity DataEC50:  2.80E+4nMAssay Description:Positive allosteric modulation of GluN2A receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50503144(CHEBI:35420 | CHEMBL1179605)
Affinity DataEC50:  3.40E+4nMAssay Description:Positive allosteric modulation of EGFP-fused human GluN2A receptor expressed in HEK293T cells assessed as increase in glycine-induced channel current...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50503145(CHEMBL4456824)
Affinity DataEC50:  1.00E+5nMAssay Description:Positive allosteric modulation of GluN2A receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50503147(CHEMBL4435232)
Affinity DataEC50:  3.20E+3nMAssay Description:Positive allosteric modulation of GluN2A receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50503144(CHEBI:35420 | CHEMBL1179605)
Affinity DataEC50:  2.10E+4nMAssay Description:Positive allosteric modulation of GluN2A receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50436060(CHEMBL2397100 | US10273214, Example 1390)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of GluN2A receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50503148(CHEMBL4583809)
Affinity DataEC50:  2.43E+3nMAssay Description:Positive allosteric modulation of GluN2A receptor (unknown origin) expressed in HEK cell assessed as increase in glycine-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50503143(CHEMBL4515734)
Affinity DataEC50:  8.50E+3nMAssay Description:Positive allosteric modulation of GluN2A receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50289910(1N-[21-(2-aminoethoxy)-3-(3-amino-1-hydroxypropyl)...)
Affinity DataIC50: 1nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50289923(1N-[21-(2-aminoethoxy)-3-[3-(1,4-diaminobutylcarbo...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50289914(1N-[21-(2-aminoethoxy)-3-[3-(1,5-diaminopentylcarb...)
Affinity DataIC50: 3nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50289922(1N-[3-[3-(1,4-diaminobutylcarboxamido)-1-hydroxypr...)
Affinity DataIC50: 3nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50289924(1N-[21-(2-aminoethoxy)-3-[3-(1,2-diaminoethylcarbo...)
Affinity DataIC50: 4nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50289917(1N-[21-(2-aminoethoxy)-3-[3-(1,3-diaminopropylcarb...)
Affinity DataIC50: 6nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50503151(CHEMBL4450420)
Affinity DataIC50: 7.90nMAssay Description:Negative allosteric modulation of human GluN2A receptor expressed in HEK cells assessed as reduction in 3 uM glycine/glutamate-induced intracellular ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50289909(1N-[3-[3-(1,5-diaminopentylcarboxamido)-1-hydroxyp...)
Affinity DataIC50: 10nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50289919(10,12-Dimethyl-tetradecanoic acid [3-(3-amino-1-hy...)
Affinity DataIC50: 10nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50289918(1N-[3-(3-aminomethylcarboxamido-1-hydroxypropyl)-6...)
Affinity DataIC50: 15nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50289913(1N-[3-[3-(4-aminobutylcarboxamido)-1-hydroxypropyl...)
Affinity DataIC50: 20nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50289920(1N-[3-[3-(2-aminoethylcarboxamido)-1-hydroxypropyl...)
Affinity DataIC50: 25nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50503154(CHEMBL4555447)
Affinity DataIC50: 27nMAssay Description:Negative allosteric modulation of human GluN2A receptor expressed in HEK cells assessed as reduction in 3 uM glycine/glutamate-induced intracellular ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50289911(1N-[3-[3-(1,2-diaminoethylcarboxamido)-1-hydroxypr...)
Affinity DataIC50: 30nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50478216(CHEBI:600520 | Micafungin | Mycamine)
Affinity DataIC50: 39.9nMAssay Description:Inhibition of Candida glabrata isolate 5416 1,3-beta-D-glucan synthase wild type Fks1p/Fks2p W1375L mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50289915(1N-[3-[3-(3-aminopropylcarboxamido)-1-hydroxypropy...)
Affinity DataIC50: 50nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50289912(1N-[3-[3-(1,3-diaminopropylcarboxamido)-1-hydroxyp...)
Affinity DataIC50: 60nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50478216(CHEBI:600520 | Micafungin | Mycamine)
Affinity DataIC50: 69.8nMAssay Description:Inhibition of Candida glabrata isolate 42031 1,3-beta-D-glucan synthase wild type Fks1p/Fks2p D666E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50417554(ANIDULAFUNGIN)
Affinity DataIC50: 74.7nMAssay Description:Inhibition of Candida glabrata isolate 5416 1,3-beta-D-glucan synthase wild type Fks1p/Fks2p W1375L mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50417554(ANIDULAFUNGIN)
Affinity DataIC50: 75.9nMAssay Description:Inhibition of Candida glabrata isolate 234 1,3-beta-D-glucan synthase wild type Fks1p/Fks2p F659V mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50478216(CHEBI:600520 | Micafungin | Mycamine)
Affinity DataIC50: 79.2nMAssay Description:Inhibition of Candida glabrata isolate 41400 1,3-beta-D-glucan synthase wild type Fks1p/Fks2p D666G mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50417554(ANIDULAFUNGIN)
Affinity DataIC50: 87.3nMAssay Description:Inhibition of Candida glabrata isolate 51916 1,3-beta-D-glucan synthase wild type Fks1p/Fks2p P667T mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50478216(CHEBI:600520 | Micafungin | Mycamine)
Affinity DataIC50: 87.3nMAssay Description:Inhibition of Candida glabrata isolate 51916 1,3-beta-D-glucan synthase wild type Fks1p/Fks2p P667T mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50478216(CHEBI:600520 | Micafungin | Mycamine)
Affinity DataIC50: 89.4nMAssay Description:Inhibition of Candida glabrata isolate 234 1,3-beta-D-glucan synthase wild type Fks1p/Fks2p F659V mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50289916(1N-[3-[3-(5-aminopentylcarboxamido)-1-hydroxypropy...)
Affinity DataIC50: 90nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50236939(CHEMBL2333945)
Affinity DataIC50: 109nMAssay Description:Negative allosteric modulation of eGFP-fused human GluN2A receptor expressed in HEK293T cells assessed as inhibition of NMDA-induced channel current ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2019
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50236939(CHEMBL2333945)
Affinity DataIC50: 110nMAssay Description:Negative allosteric modulation of human GluN2A receptor expressed in HEK cells assessed as reduction in glycine/glutamate-induced intracellular calci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50417554(ANIDULAFUNGIN)
Affinity DataIC50: 111nMAssay Description:Inhibition of Candida glabrata isolate 42031 1,3-beta-D-glucan synthase wild type Fks1p/Fks2p D666E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50478215(CHEBI:474180 | Cancidas | Caspofungin | Caspofungi...)
Affinity DataIC50: 115nMAssay Description:Inhibition of Candida glabrata isolate 234 1,3-beta-D-glucan synthase wild type Fks1p/Fks2p F659V mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50503154(CHEMBL4555447)
Affinity DataIC50: 143nMAssay Description:Negative allosteric modulation of human GluN2A receptor expressed in xenopus laevis oocytes assessed as reduction in 3 uM glycine-induced channel cur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50417554(ANIDULAFUNGIN)
Affinity DataIC50: 154nMAssay Description:Inhibition of Candida glabrata isolate 41400 1,3-beta-D-glucan synthase wild type Fks1p/Fks2p D666G mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50478215(CHEBI:474180 | Cancidas | Caspofungin | Caspofungi...)
Affinity DataIC50: 166nMAssay Description:Inhibition of Candida glabrata isolate 51916 1,3-beta-D-glucan synthase wild type Fks1p/Fks2p P667T mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50503151(CHEMBL4450420)
Affinity DataIC50: 198nMAssay Description:Negative allosteric modulation of human GluN2A receptor expressed in xenopus laevis oocytes assessed as reduction in 3 uM glycine-induced channel cur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50478215(CHEBI:474180 | Cancidas | Caspofungin | Caspofungi...)
Affinity DataIC50: 258nMAssay Description:Inhibition of Candida glabrata isolate 42031 1,3-beta-D-glucan synthase wild type Fks1p/Fks2p D666E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50289921(10,12-Dimethyl-tetradecanoic acid [3-(3-acetylamin...)
Affinity DataIC50: 300nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50236939(CHEMBL2333945)
Affinity DataIC50: 320nMAssay Description:Negative allosteric modulation of human GluN2A receptor expressed in xenopus laevis oocytes assessed as reduction in 3 uM glycine-induced channel cur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50236939(CHEMBL2333945)
Affinity DataIC50: 340nMAssay Description:Negative allosteric modulation of human GluN2A receptor expressed in HEK cells assessed as reduction in 3 uM glycine/glutamate-induced intracellular ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50478215(CHEBI:474180 | Cancidas | Caspofungin | Caspofungi...)
Affinity DataIC50: 507nMAssay Description:Inhibition of Candida glabrata isolate 41400 1,3-beta-D-glucan synthase wild type Fks1p/Fks2p D666G mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50478215(CHEBI:474180 | Cancidas | Caspofungin | Caspofungi...)
Affinity DataIC50: 608nMAssay Description:Inhibition of Candida glabrata isolate 5416 1,3-beta-D-glucan synthase wild type Fks1p/Fks2p W1375L mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50417554(ANIDULAFUNGIN)
Affinity DataIC50: 752nMAssay Description:Inhibition of Candida glabrata isolate 41026 1,3-beta-D-glucan synthase wild type Fks1p/Fks2p F659S mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50478216(CHEBI:600520 | Micafungin | Mycamine)
Affinity DataIC50: 839nMAssay Description:Inhibition of Candida glabrata isolate 41026 1,3-beta-D-glucan synthase wild type Fks1p/Fks2p F659S mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50478215(CHEBI:474180 | Cancidas | Caspofungin | Caspofungi...)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of Candida glabrata isolate 41026 1,3-beta-D-glucan synthase wild type Fks1p/Fks2p F659S mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
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