Compile Data Set for Download or QSAR
Report error Found 8 of affinity data for UniProtKB/TrEMBL: A0SYQ0
TargetProstaglandin E synthase(Dog)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50194138(CHEMBL3928608)
Affinity DataIC50: 11nMAssay Description:Inhibition of dog mPGES-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin E synthase(Dog)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50194138(CHEMBL3928608)
Affinity DataIC50: 23nMAssay Description:Inhibition of mPGES-1 in dog whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin E synthase(Dog)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50028854(CHEMBL3342693)
Affinity DataIC50: 139nMAssay Description:Inhibition of mPGES1 in LPS-induced dog whole blood assessed as suppression of PGE2 response pre-incubated for 30 mins followed by LPS addition and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetProstaglandin E synthase(Dog)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50099410(CHEMBL3342849)
Affinity DataIC50: 154nMAssay Description:Inhibition of mPGES-1 in dog whole blood assessed as inhibition of LPS-induced PGE2 production after overnight incubationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2016
Entry Details Article
PubMed
TargetProstaglandin E synthase(Dog)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50393042(CHEMBL2152712)
Affinity DataIC50: 555nMAssay Description:Inhibition of mPGES1 in LPS-induced dog whole blood assessed as suppression of PGE2 response pre-incubated for 30 mins followed by LPS addition and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin E synthase(Dog)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50460531(CHEMBL4226545)
Affinity DataIC50: 3.03E+3nMAssay Description:Inhibition of mPGES1 in dog whole blood assessed as reduction in LPS-induced PGE2 production measured after 20 to 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Dog)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50460534(CHEMBL4229061)
Affinity DataIC50: 3.54E+3nMAssay Description:Inhibition of mPGES1 in dog whole blood assessed as reduction in LPS-induced PGE2 production measured after 20 to 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Dog)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50460528(CHEMBL4224969)
Affinity DataIC50: 6.22E+3nMAssay Description:Inhibition of mPGES1 in dog whole blood assessed as reduction in LPS-induced PGE2 production measured after 20 to 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed