Compile Data Set for Download or QSAR
Report error Found 2 of affinity data for UniProtKB/TrEMBL: A0A0B4ZMU3
TargetDihydrofolate reductase(Streptococcus pneumoniae)
Arpida

LigandPNGBDBM18071(5-chloro-3-({4-[(2,4-diaminopyrimidin-5-yl)methyl]...)
Affinity DataKi:  9nM ΔG°:  -46.7kJ/mole IC50: 90nMpH: 7.0 T: 2°CAssay Description:Activity was measured as a change in absorbance over time at a wavelength of 340 nm (A340), so as to monitor the disappearance of NADPH. After incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2007
Entry Details

TargetDihydrofolate reductase(Streptococcus pneumoniae)
Arpida

LigandPNGBDBM18069(CHEMBL22 | TMP | Trimethoprim (TMP) | 5-[(3,4,5-tr...)
Affinity DataKi:  5.60E+3nM ΔG°:  -30.5kJ/mole IC50: 4.20E+4nMpH: 7.0 T: 2°CAssay Description:Activity was measured as a change in absorbance over time at a wavelength of 340 nm (A340), so as to monitor the disappearance of NADPH. After incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2007
Entry Details