BDBM6623 3-{5-[(tert-butylamino)methyl]-1H-pyrazol-3-yl}-1-{5-oxo-1H,2H,3H,5H,9bH-benzo[a]pyrrolizin-9-yl}urea::5-alkylaminomethyl pyrazole-3-yl urea deriv. 9d::N-{5-[(tert-Butylamino)methyl]-1H-pyrazol-3-yl}-N -(5-oxo-2,3,5,9b-tetrahydro-1H-pyrrolo[2,1-a]isoindol-9-yl)-urea

SMILES CC(C)(C)NCc1cc(NC(=O)Nc2cccc3C(=O)N4CCCC4c23)[nH]n1

InChI Key InChIKey=GTZWWDDACCTQQM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6623   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM6623(N-{5-[(tert-Butylamino)methyl]-1H-pyrazol-3-yl}-N ...)
Affinity DataIC50: 56nMAssay Description:Src, Lck, Flt-1, ZAP, EGFR, FGFR1, and PFGFR-beta were assayed in the Merck research laboratory (Homogeneous proximity tyrosine kinase assays: scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2005
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM6623(N-{5-[(tert-Butylamino)methyl]-1H-pyrazol-3-yl}-N ...)
Affinity DataIC50: 9.80E+3nMAssay Description:Src, Lck, Flt-1, ZAP, EGFR, FGFR1, and PFGFR-beta were assayed in the Merck research laboratory (Homogeneous proximity tyrosine kinase assays: scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2005
Entry Details Article
PubMed