BDBM50221594 4'-(6,7-dimethoxy-2,4-dihydro-indeno[1,2-c]pyrazol-3-yl)-biphenyl-3-ylamine::CHEMBL247610::Chk1_116

SMILES COc1cc2Cc3c(n[nH]c3-c2cc1OC)-c1ccc(cc1)-c1cccc(N)c1

InChI Key InChIKey=KOBAJBSVGOQLPY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50221594   

TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221594(CHEMBL247610 | Chk1_116 | 4'-(6,7-dimethoxy-2,4-di...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221594(CHEMBL247610 | Chk1_116 | 4'-(6,7-dimethoxy-2,4-di...)
Affinity DataIC50: 1.00E+4nMAssay Description:Abbott Kinase Enzymatics_CHK1/289 CDC25c - IC50(uM) (IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2012
Entry Details PubMed