Compile Data Set for Download or QSAR
Report error Found 580 Enz. Inhib. hit(s) with all data for entry = 1513
TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328480((S)-1,1,1-trifluoro-2-methylpropan-2- yl (2-(aceta...)
Affinity DataIC50: 2.19nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328551((S)-1,1,1-trifluoro-2-methylpropan-2-yl (2-(acetam...)
Affinity DataIC50: 2.19nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328481((S)-1,1,1-trifluoro-2-methylpropan-2- yl (2-(aceta...)
Affinity DataIC50: 2.43nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328552((S)-1,1,1-trifluoro-2-methylpropan-2-yl (2-(acetam...)
Affinity DataIC50: 2.48nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328494((S)-1,1,1-trifluoro-2-methylpropan-2- yl (2-(aceta...)
Affinity DataIC50: 2.57nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328477((S)-1,1,1-trifluoro-2-methylpropan-2- yl (2-(aceta...)
Affinity DataIC50: 2.64nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328838((S)-tert-butyl (4-((3-chloro-4- fluorophenyl)sulfo...)
Affinity DataIC50: 2.68nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328435((S)-tert-butyl (2- (acetamidomethyl)-4-((3- (trifl...)
Affinity DataIC50: 2.70nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328637((S)-1,1,1-trifluoro-3,3- dimethylbutan-2-yl ((S)-2...)
Affinity DataIC50: 2.77nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328495((S)-1,1,1-trifluoro-2-methylpropan-2- yl (2-(aceta...)
Affinity DataIC50: 2.86nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328819(US9663502, 36o | (S)-tert-butyl (4-((3-chloro-4- f...)
Affinity DataIC50: 2.92nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328811(US9663502, 36G | (S)-1,1,1-trifluoro-2-methylpropa...)
Affinity DataIC50: 2.99nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328840((S)-1,1,1-trifluoro-2-methylpropan-2-yl (4-((3-chl...)
Affinity DataIC50: 3.05nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328797(US9663502, 34CY | 1,1,1-trifluoro-2-methylpropan- ...)
Affinity DataIC50: 3.07nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328605((S)-1- (trifluoromethyl)cyclohexyl (2-(acetamidom...)
Affinity DataIC50: 3.24nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328874((S)-1,1,1-trifluoro-2-methylpropan-2-yl (4-((4-flu...)
Affinity DataIC50: 3.28nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328479((S)-1,1,1-trifluoro-2-methylpropan-2- yl (2-(aceta...)
Affinity DataIC50: 3.35nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328740(US9663502, 34AS | (S)-1,1,1-trifluoro-2- methylpro...)
Affinity DataIC50: 3.49nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328509((S)-1,1,1-trifluoro-2-methylpropan-2- yl (2-(aceta...)
Affinity DataIC50: 3.61nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328626(2-(trifluoromethyl)cyclohexyl ((S)- 2-(acetamidome...)
Affinity DataIC50: 3.67nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328630((1S,2R)-2- (trifluoromethyl)cyclohexyl ((S)-2- (ac...)
Affinity DataIC50: 3.77nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328935(2,2,2-trifluoro-1,1-dimethylethyl [(2S)-4- {[2-(2-...)
Affinity DataIC50: 3.80nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328805(US9663502, 36A | (S)-4-((2- (cyclopropanesulfonami...)
Affinity DataIC50: 3.82nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328828(US9663502, 36X | (S)-4-((2- (cyclopropanesulfonami...)
Affinity DataIC50: 3.84nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328798(US9663502, 34CZ | (S)-1,1,1-trifluoro-2- methylpro...)
Affinity DataIC50: 3.86nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328756(US9663502, 34Bi | (S)-1,1,1-trifluoro-2- methylpro...)
Affinity DataIC50: 3.87nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328716(US9663502, 34U | (S)-1,1,1-trifluoro-2- methylprop...)
Affinity DataIC50: 3.92nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328837(US9663502, 37G | (S)-1,1,1-trifluoro-2-methylpropa...)
Affinity DataIC50: 3.93nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328742(US9663502, 34AU | 1,1,1-trifluoro-2-methylpropan- ...)
Affinity DataIC50: 3.94nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328821(US9663502, 36Q | (S)-4-((6-((tert- butoxycarbonyl)...)
Affinity DataIC50: 3.96nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328448((S)-tert-butyl (2- (acetamidomethyl)-4-((4-fluoro-...)
Affinity DataIC50: 3.99nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328940(2,2,2-trifluoro-1,1-dimethylethyl [(2S)-2- [(acety...)
Affinity DataIC50: 4.01nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328833(US9663502, 37C | (S)-tert-butyl (4-((4-fluoro-3- m...)
Affinity DataIC50: 4.09nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328804(US9663502, 35)
Affinity DataIC50: 4.14nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328812(US9663502, 36H | (S)-tert-butyl (2- (cyclopropanes...)
Affinity DataIC50: 4.16nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328854((S)-1,1,1-trifluoro-2-methylpropan-2- yl (2- ((chl...)
Affinity DataIC50: 4.18nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328446((S)-tert-butyl (2- (acetamidomethyl)-4-((3-chloro-...)
Affinity DataIC50: 4.25nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328814(US9663502, 36J | (S)-1,1,1-trifluoro-2-methylpropa...)
Affinity DataIC50: 4.27nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328794(US9663502, 34CV | 1,1,1-trifluoro-2-methylpropan- ...)
Affinity DataIC50: 4.35nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328818(US9663502, 36N | (S)-1,1,1-trifluoro-2-methylpropa...)
Affinity DataIC50: 4.35nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328490((S)-1,1,1-trifluoro-2-methylpropan-2- yl (2-(aceta...)
Affinity DataIC50: 4.36nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328752(US9663502, 34BE | (S)-1,1,1-trifluoro-2- methylpro...)
Affinity DataIC50: 4.36nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328525((S)-1,1,1-trifluoro-2-methylpropan-2- yl (2-(aceta...)
Affinity DataIC50: 4.38nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328755(US9663502, 34BH | 1,1,1-trifluoro-2-methylpropan- ...)
Affinity DataIC50: 4.38nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328806(US9663502, 36B | (S)-1,1,1-trifluoro-2-methylpropa...)
Affinity DataIC50: 4.38nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328876((S)-1,1,1-trifluoro-2- methylpropan-2-yl (4-((3-ch...)
Affinity DataIC50: 4.38nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328771(US9663502, 34BX | 1,1,1-trifluoro-2-methylpropan- ...)
Affinity DataIC50: 4.47nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328757(US9663502, 34BJ | (S)-1,1,1-trifluoro-2- methylpro...)
Affinity DataIC50: 4.51nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328449((S)-tert-butyl (2- (acetamidomethyl)-4-((5- (trifl...)
Affinity DataIC50: 4.59nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328788(US9663502, 34Co | 1,1,1-trifluoro-2-methylpropan- ...)
Affinity DataIC50: 4.59nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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