Compile Data Set for Download or QSAR
Report error Found 102 Enz. Inhib. hit(s) with all data for entry = 794
TargetC-X-C chemokine receptor type 3(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM291172(2-hydroxy-N,N-dimethyl-3-(2-{[(5-methylfuran-2-yl)...)
Affinity DataIC50: 1.30nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
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TargetC-C chemokine receptor type 6(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM291181(6-chloro-2-hydroxy-N,N-dimethyl-3-(2-{[(5-methylfu...)
Affinity DataIC50: 1.60nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-C chemokine receptor type 6(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM291172(2-hydroxy-N,N-dimethyl-3-(2-{[(5-methylfuran-2-yl)...)
Affinity DataIC50: 2nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
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TargetC-C chemokine receptor type 6(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM291172(2-hydroxy-N,N-dimethyl-3-(2-{[(5-methylfuran-2-yl)...)
Affinity DataIC50: 2.20nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-C chemokine receptor type 6(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM236791(US9388149, 22 | US9580412, Example 22)
Affinity DataIC50: 2.20nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-C chemokine receptor type 6(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM236795(US9388149, 2 (Enantiomer 1 of diastereoisomer 2) |...)
Affinity DataIC50: 6nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
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TargetC-C chemokine receptor type 4(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM236789(US9388149, 20 | US9580412, Example 20)
Affinity DataIC50: 7.20nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
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TargetC-C chemokine receptor type 6(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM236795(US9388149, 2 (Enantiomer 1 of diastereoisomer 2) |...)
Affinity DataIC50: 8nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
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TargetC-C chemokine receptor type 4(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM236788(US9388149, 19 | US9580412, Example 19)
Affinity DataIC50: 8.10nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
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TargetC-C chemokine receptor type 6(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM236789(US9388149, 20 | US9580412, Example 20)
Affinity DataIC50: 8.80nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
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TargetC-C chemokine receptor type 4(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM236791(US9388149, 22 | US9580412, Example 22)
Affinity DataIC50: 9.40nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
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TargetC-C chemokine receptor type 6(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM291177(US9580412, Example 6 | methyl (R)-1-[2-hydroxy-3-(...)
Affinity DataIC50: 9.70nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-C chemokine receptor type 6(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM236788(US9388149, 19 | US9580412, Example 19)
Affinity DataIC50: 11nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 2(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM236795(US9388149, 2 (Enantiomer 1 of diastereoisomer 2) |...)
Affinity DataIC50: 15nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
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TargetC-X-C chemokine receptor type 2(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM236787(US9388149, 18 | US9580412, Example 18)
Affinity DataIC50: 15nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 2(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM291181(6-chloro-2-hydroxy-N,N-dimethyl-3-(2-{[(5-methylfu...)
Affinity DataIC50: 16nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 2(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM236791(US9388149, 22 | US9580412, Example 22)
Affinity DataIC50: 17nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 1(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM291181(6-chloro-2-hydroxy-N,N-dimethyl-3-(2-{[(5-methylfu...)
Affinity DataIC50: 20nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 2(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM236788(US9388149, 19 | US9580412, Example 19)
Affinity DataIC50: 20nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 2(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM236789(US9388149, 20 | US9580412, Example 20)
Affinity DataIC50: 21nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 2(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM236785(US9388149, 16 | US9580412, Example 16)
Affinity DataIC50: 23nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 2(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM291177(US9580412, Example 6 | methyl (R)-1-[2-hydroxy-3-(...)
Affinity DataIC50: 30nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 1(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM236791(US9388149, 22 | US9580412, Example 22)
Affinity DataIC50: 30nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 1(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM236787(US9388149, 18 | US9580412, Example 18)
Affinity DataIC50: 36nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 2(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM291177(US9580412, Example 6 | methyl (R)-1-[2-hydroxy-3-(...)
Affinity DataIC50: 37nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-C chemokine receptor type 4(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM291181(6-chloro-2-hydroxy-N,N-dimethyl-3-(2-{[(5-methylfu...)
Affinity DataIC50: 39nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 1(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM236788(US9388149, 19 | US9580412, Example 19)
Affinity DataIC50: 42nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 1(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM236789(US9388149, 20 | US9580412, Example 20)
Affinity DataIC50: 43nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 2(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM291188(3-{[(5-methylfuran-2-yl)-(tetrahydrothiophen-2-yl)...)
Affinity DataIC50: 44nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 2(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM291179(2-hydroxy-N-methyl-3-(2-{[(S)-(5-methylfuran-2-yl)...)
Affinity DataIC50: 47nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-C chemokine receptor type 4(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM236795(US9388149, 2 (Enantiomer 1 of diastereoisomer 2) |...)
Affinity DataIC50: 52nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 2(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM291172(2-hydroxy-N,N-dimethyl-3-(2-{[(5-methylfuran-2-yl)...)
Affinity DataIC50: 53nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 3(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM291172(2-hydroxy-N,N-dimethyl-3-(2-{[(5-methylfuran-2-yl)...)
Affinity DataIC50: 55nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-C chemokine receptor type 6(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM236787(US9388149, 18 | US9580412, Example 18)
Affinity DataIC50: 60nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 2(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM291192((−)-6-chloro-2-hydroxy-N,N-dimethyl-3-(2-{[(...)
Affinity DataIC50: 69nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 1(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM236795(US9388149, 2 (Enantiomer 1 of diastereoisomer 2) |...)
Affinity DataIC50: 77nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 2(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM291180(methyl {[2-hydroxy-3-(2-{[(5-methylfuran-2-yl)-(te...)
Affinity DataIC50: 80nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 2(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM236781(US9388149, 12 | US9580412, Example 12)
Affinity DataIC50: 83nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 1(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM291179(2-hydroxy-N-methyl-3-(2-{[(S)-(5-methylfuran-2-yl)...)
Affinity DataIC50: 85nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 2(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM291177(US9580412, Example 6 | methyl (R)-1-[2-hydroxy-3-(...)
Affinity DataIC50: 86nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 1(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM291180(methyl {[2-hydroxy-3-(2-{[(5-methylfuran-2-yl)-(te...)
Affinity DataIC50: 89nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 3(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM291181(6-chloro-2-hydroxy-N,N-dimethyl-3-(2-{[(5-methylfu...)
Affinity DataIC50: 93nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-C chemokine receptor type 4(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM236787(US9388149, 18 | US9580412, Example 18)
Affinity DataIC50: 97nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 2(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM236805(US9388149, 5 | US9580412, Example 5)
Affinity DataIC50: 106nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 1(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM291177(US9580412, Example 6 | methyl (R)-1-[2-hydroxy-3-(...)
Affinity DataIC50: 108nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 2(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM236804(US9388149, 4 | US9580412, Example 4)
Affinity DataIC50: 109nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 1(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM291192((−)-6-chloro-2-hydroxy-N,N-dimethyl-3-(2-{[(...)
Affinity DataIC50: 113nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 2(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM291179(2-hydroxy-N-methyl-3-(2-{[(S)-(5-methylfuran-2-yl)...)
Affinity DataIC50: 115nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 3(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM291177(US9580412, Example 6 | methyl (R)-1-[2-hydroxy-3-(...)
Affinity DataIC50: 140nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 3(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM236791(US9388149, 22 | US9580412, Example 22)
Affinity DataIC50: 150nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent

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