Compile Data Set for Download or QSAR
Report error Found 236 Enz. Inhib. hit(s) with all data for entry = 7770
TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215446(US9296745, 1)
Affinity DataIC50: 1.70nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215552(US9296745, 109-A | US9296745, 190 | US9296745, 109...)
Affinity DataIC50: 2.10nMAssay Description:For evaluation of the effects of DGAT2 inhibitors in a cell-based setting, cryopreserved human hepatocytes (Lot QOC, Celsis, Chicago, Ill.) were thaw...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215661(US9296745, 199)
Affinity DataIC50: 2.5nMAssay Description:For evaluation of the effects of DGAT2 inhibitors in a cell-based setting, cryopreserved human hepatocytes (Lot QOC, Celsis, Chicago, Ill.) were thaw...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215447(US9296745, 2)
Affinity DataIC50: 2.71nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215551(US9296745, 108)
Affinity DataIC50: 2.80nMAssay Description:For evaluation of the effects of DGAT2 inhibitors in a cell-based setting, cryopreserved human hepatocytes (Lot QOC, Celsis, Chicago, Ill.) were thaw...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215487(US9296745, 42)
Affinity DataIC50: 3.18nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215599(US9296745, 158)
Affinity DataIC50: 3.58nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215486(US9296745, 41 | US9296745, 154)
Affinity DataIC50: 4.56nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215629(US9296745, 196-A | US9296745, 196-B)
Affinity DataIC50: 4.60nMAssay Description:For evaluation of the effects of DGAT2 inhibitors in a cell-based setting, cryopreserved human hepatocytes (Lot QOC, Celsis, Chicago, Ill.) were thaw...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215448(US9296745, 3)
Affinity DataIC50: 4.82nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215568(US9296745, 124)
Affinity DataIC50: 5.27nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215552(US9296745, 109-A | US9296745, 190 | US9296745, 109...)
Affinity DataIC50: 5.5nMAssay Description:For evaluation of the effects of DGAT2 inhibitors in a cell-based setting, cryopreserved human hepatocytes (Lot QOC, Celsis, Chicago, Ill.) were thaw...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215660(US9296745, 197)
Affinity DataIC50: 5.5nMAssay Description:For evaluation of the effects of DGAT2 inhibitors in a cell-based setting, cryopreserved human hepatocytes (Lot QOC, Celsis, Chicago, Ill.) were thaw...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215549(US9296745, 106)
Affinity DataIC50: 5.68nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215594(US9296745, 153 | US9296745, 182)
Affinity DataIC50: 6.03nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215579(US9296745, 136)
Affinity DataIC50: 6.32nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215485(US9296745, 40)
Affinity DataIC50: 6.47nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215449(US9296745, 4)
Affinity DataIC50: 6.64nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215484(US9296745, 39)
Affinity DataIC50: 6.85nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215572(US9296745, 128)
Affinity DataIC50: 7.16nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215488(US9296745, 43 | US9296745, 155)
Affinity DataIC50: 7.41nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215631(US9296745, 198)
Affinity DataIC50: 7.80nMAssay Description:For evaluation of the effects of DGAT2 inhibitors in a cell-based setting, cryopreserved human hepatocytes (Lot QOC, Celsis, Chicago, Ill.) were thaw...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215483(US9296745, 38)
Affinity DataIC50: 7.81nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215517(US9296745, 73)
Affinity DataIC50: 7.90nMAssay Description:For evaluation of the effects of DGAT2 inhibitors in a cell-based setting, cryopreserved human hepatocytes (Lot QOC, Celsis, Chicago, Ill.) were thaw...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215450(US9296745, 5)
Affinity DataIC50: 8.24nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215640(US9296745, 209)
Affinity DataIC50: 8.90nMAssay Description:For evaluation of the effects of DGAT2 inhibitors in a cell-based setting, cryopreserved human hepatocytes (Lot QOC, Celsis, Chicago, Ill.) were thaw...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215589(US9296745, 147)
Affinity DataIC50: 9.21nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215556(US9296745, 112)
Affinity DataIC50: 9.23nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215522(US9296745, 78)
Affinity DataIC50: 9.40nMAssay Description:For evaluation of the effects of DGAT2 inhibitors in a cell-based setting, cryopreserved human hepatocytes (Lot QOC, Celsis, Chicago, Ill.) were thaw...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215528(US9296745, 84)
Affinity DataIC50: 9.55nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215623(US9296745, 187)
Affinity DataIC50: 10.5nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215492(US9296745, 48)
Affinity DataIC50: 10.7nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215584(US9296745, 141)
Affinity DataIC50: 10.7nMAssay Description:For evaluation of the effects of DGAT2 inhibitors in a cell-based setting, cryopreserved human hepatocytes (Lot QOC, Celsis, Chicago, Ill.) were thaw...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215566(US9296745, 122)
Affinity DataIC50: 10.9nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215451(US9296745, 6)
Affinity DataIC50: 11.5nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215482(US9296745, 37)
Affinity DataIC50: 12.6nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215552(US9296745, 109-A | US9296745, 190 | US9296745, 109...)
Affinity DataIC50: 13.8nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215565(US9296745, 121)
Affinity DataIC50: 14.3nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215629(US9296745, 196-A | US9296745, 196-B)
Affinity DataIC50: 14.5nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215620(US9296745, 184)
Affinity DataIC50: 15.2nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215526(US9296745, 82)
Affinity DataIC50: 15.8nMAssay Description:For evaluation of the effects of DGAT2 inhibitors in a cell-based setting, cryopreserved human hepatocytes (Lot QOC, Celsis, Chicago, Ill.) were thaw...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215538(US9296745, 95)
Affinity DataIC50: 15.9nMAssay Description:For evaluation of the effects of DGAT2 inhibitors in a cell-based setting, cryopreserved human hepatocytes (Lot QOC, Celsis, Chicago, Ill.) were thaw...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215452(US9296745, 7)
Affinity DataIC50: 16.3nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215538(US9296745, 95)
Affinity DataIC50: 18.2nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215661(US9296745, 199)
Affinity DataIC50: 18.9nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215643(US9296745, 212)
Affinity DataIC50: 18.9nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215552(US9296745, 109-A | US9296745, 190 | US9296745, 109...)
Affinity DataIC50: 20.2nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215481(US9296745, 36)
Affinity DataIC50: 20.7nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215453(US9296745, 8)
Affinity DataIC50: 21.1nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2017
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM215480(US9296745, 35)
Affinity DataIC50: 21.2nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
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