Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 7369
TargetTranscription factor Jun(Human)
Stc.Unm

US Patent
LigandPNGBDBM191748(US9187397, 20m)
Affinity DataIC50: 1.40E+3nMAssay Description:Curcumin is a known inhibitor of the AP-1 activation cascade. Therefore, modification of the structure of curcumin could lead to analogs with enhance...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetNuclear factor NF-kappa-B p105 subunit(Human)
Stc.Unm

US Patent
LigandPNGBDBM191744(US9187397, 31 | US9187397, 3)
Affinity DataIC50: 3.40E+3nMAssay Description:The NF-kB activities of curcumin and analogs were determined by a cellular firefly luciferase assay. This assay utilized a commercially available cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetNuclear factor NF-kappa-B p105 subunit(Human)
Stc.Unm

US Patent
LigandPNGBDBM191744(US9187397, 31 | US9187397, 3)
Affinity DataIC50: 3.40E+3nMAssay Description:The NF-kB activities of curcumin and analogs were determined by a cellular firefly luciferase assay. This assay utilized a commercially available cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetNuclear factor NF-kappa-B p105 subunit(Human)
Stc.Unm

US Patent
LigandPNGBDBM191745(US9187397, 29)
Affinity DataIC50: 3.50E+3nMAssay Description:The NF-kB activities of curcumin and analogs were determined by a cellular firefly luciferase assay. This assay utilized a commercially available cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetTranscription factor Jun(Human)
Stc.Unm

US Patent
LigandPNGBDBM191744(US9187397, 31 | US9187397, 3)
Affinity DataIC50: 4.10E+3nMAssay Description:Curcumin is a known inhibitor of the AP-1 activation cascade. Therefore, modification of the structure of curcumin could lead to analogs with enhance...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetNuclear factor NF-kappa-B p105 subunit(Human)
Stc.Unm

US Patent
LigandPNGBDBM50067033(2,6-Bis-[1-(4-hydroxy-3-methoxy-phenyl)-meth-(E)-y...)
Affinity DataIC50: 4.20E+3nMAssay Description:The NF-kB activities of curcumin and analogs were determined by a cellular firefly luciferase assay. This assay utilized a commercially available cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetNuclear factor NF-kappa-B p105 subunit(Human)
Stc.Unm

US Patent
LigandPNGBDBM191746(US9187397, 20q)
Affinity DataIC50: 4.20E+3nMAssay Description:The NF-kB activities of curcumin and analogs were determined by a cellular firefly luciferase assay. This assay utilized a commercially available cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetNuclear factor NF-kappa-B p105 subunit(Human)
Stc.Unm

US Patent
LigandPNGBDBM50067033(2,6-Bis-[1-(4-hydroxy-3-methoxy-phenyl)-meth-(E)-y...)
Affinity DataIC50: 4.40E+3nMAssay Description:The NF-kB activities of curcumin and analogs were determined by a cellular firefly luciferase assay. This assay utilized a commercially available cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetNuclear factor NF-kappa-B p105 subunit(Human)
Stc.Unm

US Patent
LigandPNGBDBM191762(US9187397, 5)
Affinity DataIC50: 5.00E+3nMAssay Description:The NF-kB activities of curcumin and analogs were determined by a cellular firefly luciferase assay. This assay utilized a commercially available cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetTranscription factor Jun(Human)
Stc.Unm

US Patent
LigandPNGBDBM191750(US9187397, 9a)
Affinity DataIC50: 5.30E+3nMAssay Description:Curcumin is a known inhibitor of the AP-1 activation cascade. Therefore, modification of the structure of curcumin could lead to analogs with enhance...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetNuclear factor NF-kappa-B p105 subunit(Human)
Stc.Unm

US Patent
LigandPNGBDBM191747(US9187397, 20ag)
Affinity DataIC50: 5.40E+3nMAssay Description:The NF-kB activities of curcumin and analogs were determined by a cellular firefly luciferase assay. This assay utilized a commercially available cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetTranscription factor Jun(Human)
Stc.Unm

US Patent
LigandPNGBDBM191749(US9187397, 6a | US9187397, 2)
Affinity DataIC50: 6.00E+3nMAssay Description:Curcumin is a known inhibitor of the AP-1 activation cascade. Therefore, modification of the structure of curcumin could lead to analogs with enhance...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetNuclear factor NF-kappa-B p105 subunit(Human)
Stc.Unm

US Patent
LigandPNGBDBM191748(US9187397, 20m)
Affinity DataIC50: 6.40E+3nMAssay Description:The NF-kB activities of curcumin and analogs were determined by a cellular firefly luciferase assay. This assay utilized a commercially available cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetNuclear factor NF-kappa-B p105 subunit(Human)
Stc.Unm

US Patent
LigandPNGBDBM191749(US9187397, 6a | US9187397, 2)
Affinity DataIC50: 6.70E+3nMAssay Description:The NF-kB activities of curcumin and analogs were determined by a cellular firefly luciferase assay. This assay utilized a commercially available cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetNuclear factor NF-kappa-B p105 subunit(Human)
Stc.Unm

US Patent
LigandPNGBDBM191749(US9187397, 6a | US9187397, 2)
Affinity DataIC50: 6.70E+3nMAssay Description:The NF-kB activities of curcumin and analogs were determined by a cellular firefly luciferase assay. This assay utilized a commercially available cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetTranscription factor Jun(Human)
Stc.Unm

US Patent
LigandPNGBDBM50067033(2,6-Bis-[1-(4-hydroxy-3-methoxy-phenyl)-meth-(E)-y...)
Affinity DataIC50: 7.30E+3nMAssay Description:Curcumin is a known inhibitor of the AP-1 activation cascade. Therefore, modification of the structure of curcumin could lead to analogs with enhance...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetNuclear factor NF-kappa-B p105 subunit(Human)
Stc.Unm

US Patent
LigandPNGBDBM191750(US9187397, 9a)
Affinity DataIC50: 7.60E+3nMAssay Description:The NF-kB activities of curcumin and analogs were determined by a cellular firefly luciferase assay. This assay utilized a commercially available cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetTranscription factor Jun(Human)
Stc.Unm

US Patent
LigandPNGBDBM191745(US9187397, 29)
Affinity DataIC50: 8.20E+3nMAssay Description:Curcumin is a known inhibitor of the AP-1 activation cascade. Therefore, modification of the structure of curcumin could lead to analogs with enhance...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetNuclear factor NF-kappa-B p105 subunit(Human)
Stc.Unm

US Patent
LigandPNGBDBM191758(US9187397, 1 (curcumin) | US9187397, 3a)
Affinity DataIC50: 8.20E+3nMAssay Description:The NF-kB activities of curcumin and analogs were determined by a cellular firefly luciferase assay. This assay utilized a commercially available cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetNuclear factor NF-kappa-B p105 subunit(Human)
Stc.Unm

US Patent
LigandPNGBDBM191763(US9187406, Curcumin | US9187397, 1 | curcumin | US...)
Affinity DataIC50: 8.20E+3nMAssay Description:The NF-kB activities of curcumin and analogs were determined by a cellular firefly luciferase assay. This assay utilized a commercially available cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetTranscription factor Jun(Human)
Stc.Unm

US Patent
LigandPNGBDBM191747(US9187397, 20ag)
Affinity DataIC50: 8.30E+3nMAssay Description:Curcumin is a known inhibitor of the AP-1 activation cascade. Therefore, modification of the structure of curcumin could lead to analogs with enhance...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetTranscription factor Jun(Human)
Stc.Unm

US Patent
LigandPNGBDBM191746(US9187397, 20q)
Affinity DataIC50: 1.17E+4nMAssay Description:Curcumin is a known inhibitor of the AP-1 activation cascade. Therefore, modification of the structure of curcumin could lead to analogs with enhance...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetTranscription factor Jun(Human)
Stc.Unm

US Patent
LigandPNGBDBM191758(US9187397, 1 (curcumin) | US9187397, 3a)
Affinity DataIC50: 1.28E+4nMAssay Description:Curcumin is a known inhibitor of the AP-1 activation cascade. Therefore, modification of the structure of curcumin could lead to analogs with enhance...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent