Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 7289
TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM161329(US9163042, 1a | US9051270, 114 | US10087143, Compo...)
Affinity DataIC50: 1nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
Go to US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM161326(US9163042, 2a | US9051270, 111 | US10087143, Compo...)
Affinity DataIC50: 3nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
Go to US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM186571(US9163042, 1 | US10787472, Compound 1)
Affinity DataIC50: 4nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
Go to US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM161328(US9163042, 3a | US9051270, 113 | US10087143, Compo...)
Affinity DataIC50: 6nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
Go to US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM161245(US9163042, 4a | US9051270, 30 | US10087143, Compou...)
Affinity DataIC50: 11nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
Go to US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM161294(US9163042, 5a | US9051270, 82 | US9051270, 79 | US...)
Affinity DataIC50: 11nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
Go to US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM161303(US9163042, 6a | US9051270, 88 | US10087143, Compou...)
Affinity DataIC50: 12nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
Go to US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM161285(US9163042, 7a | US9051270, 70 | US9758483, Compoun...)
Affinity DataIC50: 13nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
Go to US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM161287(US9163042, 8a | US9051270, 73 | US9051270, 72 | US...)
Affinity DataIC50: 13nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
Go to US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM161225(US9163042, 9a | US9051270, 10 | US10087143, Compou...)
Affinity DataIC50: 14nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
Go to US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM161246(US9163042, 10a | US9051270, 106 | US9051270, 31 | ...)
Affinity DataIC50: 17nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
Go to US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM186572(US9163042, 2)
Affinity DataIC50: 28nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
Go to US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM161244(US9163042, 11a | US9051270, 29 | US10087143, Compo...)
Affinity DataIC50: 28nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
Go to US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM161283(US9163042, 12a | US9051270, 68 | US10087143, Compo...)
Affinity DataIC50: 30nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
Go to US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM161235(US9163042, 13a | US9051270, 20 | US10087143, Compo...)
Affinity DataIC50: 30nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
Go to US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM161281(US9163042, 14a | US9051270, 66 | US10087143, Compo...)
Affinity DataIC50: 37nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
Go to US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM161243(US9163042, 15a | US9051270, 28 | US10087143, Compo...)
Affinity DataIC50: 44nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
Go to US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM161222(US9163042, 16a | US9051270, 7 | US10087143, Compou...)
Affinity DataIC50: 50nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
Go to US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM161290(US9163042, 17a | US9051270, 75 | US10087143, Compo...)
Affinity DataIC50: 51nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
Go to US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM161217(US9163042, 18a | US9051270, 2 | US10087143, Compou...)
Affinity DataIC50: 54nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
Go to US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM186574(US9163042, 10 | US10787472, Compound 10)
Affinity DataIC50: 86nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
Go to US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM186575(US9163042, 13 | US10787472, Compound 13)
Affinity DataIC50: 329nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
Go to US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM186573(US9163042, 9 | US10787472, Compound 9 | US20230303...)
Affinity DataIC50: 330nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
Go to US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM186576(US9163042, 18 | US10787472, Compound 18)
Affinity DataIC50: 457nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
Go to US Patent