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Found
70
Enz. Inhib. hit(s) with all data for entry = 12839
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732731
(US20250115572, Ex-1)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.5nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732735
((S)-4-(2,2-difluoro-7-((5-methoxy-7-methyl-1H-indo...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.5nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732785
(US20250115572, Ex-55)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.600nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732737
(US20250115572, Ex-7)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.800nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732751
((S)-4-(7-((5-cyclopropyl-7-methyl-1H-indol-4-yl)me...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.40nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732763
(US20250115572, Ex-33)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.60nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732792
(US20250115572, Ex-62)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.90nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732796
(US20250115572, Ex-66)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732794
(US20250115572, Ex-64)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732739
(4-(2-fluoro-7-((5-methoxy-7-methyl-1H-indol-4-yl)m...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732789
(US20250115572, Ex-59)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732784
(US20250115572, Ex-54)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.20nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732752
(US20250115572, Ex-22)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.40nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732777
(US20250115572, Ex-47)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.5nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732748
(4-((5S,7S)-2,2-difluoro-8-((5-methoxy-7-methyl-1H-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.40nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732788
(US20250115572, Ex-58)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.80nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732761
(US20250115572, Ex-31)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.80nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732791
(US20250115572, Ex-61)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.80nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732755
(US20250115572, Ex-25)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732781
(US20250115572, Ex-51)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.20nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732798
(US20250115572, Ex-68)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.5nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732787
(US20250115572, Ex-57)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732759
(US20250115572, Ex-29)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732779
(US20250115572, Ex-49)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.60nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732741
(US20250115572, Ex-11)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.80nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732757
(US20250115572, Ex-27)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.90nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732780
(US20250115572, Ex-50)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732750
(US20250115572, Ex-20)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.60nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732783
(US20250115572, Ex-53)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.70nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732778
(US20250115572, Ex-48)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.90nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732753
(US20250115572, Ex-23)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.90nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732775
(US20250115572, Ex-45)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9.40nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732771
(US20250115572, Ex-41)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9.60nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732774
(US20250115572, Ex-44)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9.90nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732769
(US20250115572, Ex-39)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10.3nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732767
(US20250115572, Ex-37)
Copy SMILES
Copy InChI
Affinity Data
IC50: 11.2nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732800
(US20250115572, Ex-70)
Copy SMILES
Copy InChI
Affinity Data
IC50: 14.7nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732765
(US20250115572, Ex-35)
Copy SMILES
Copy InChI
Affinity Data
IC50: 17.3nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732766
(US20250115572, Ex-36)
Copy SMILES
Copy InChI
Affinity Data
IC50: 24.5nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732743
(US20250115572, Ex-13)
Copy SMILES
Copy InChI
Affinity Data
IC50: 29.4nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732754
(US20250115572, Ex-24)
Copy SMILES
Copy InChI
Affinity Data
IC50: 31.4nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732733
(US20250115572, Ex-3)
Copy SMILES
Copy InChI
Affinity Data
IC50: 40.7nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732786
(US20250115572, Ex-56)
Copy SMILES
Copy InChI
Affinity Data
IC50: 58.6nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732760
(US20250115572, Ex-30)
Copy SMILES
Copy InChI
Affinity Data
IC50: 100nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732745
(US20250115572, Ex-15)
Copy SMILES
Copy InChI
Affinity Data
IC50: 105nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732764
(US20250115572, Ex-34)
Copy SMILES
Copy InChI
Affinity Data
IC50: 124nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732790
(US20250115572, Ex-60)
Copy SMILES
Copy InChI
Affinity Data
IC50: 152nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732782
(US20250115572, Ex-52)
Copy SMILES
Copy InChI
Affinity Data
IC50: 172nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732738
(US20250115572, Ex-8)
Copy SMILES
Copy InChI
Affinity Data
IC50: 227nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Complement factor B
(Human)
Novartis
US Patent
Ligand
BDBM732795
(US20250115572, Ex-65)
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Affinity Data
IC50: 235nM
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Target Info
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Ligand Info
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In Depth
Date in BDB:
8/22/2025
Entry Details
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