Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 12515
TargetGTPase HRas [G12V,1-166]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Genetolead
US Patent
Genetolead
US Patent
Affinity DataKd: 36nMAssay Description:Dissociation constants were obtained by monitoring changes in chemical shifts as a function of ligand concentration. The changes in chemical shifts (...More data for this Ligand-Target Pair
TargetGTPase HRas [G12V,1-166]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Genetolead
US Patent
Genetolead
US Patent
Affinity DataKd: 6.07E+3nMAssay Description:Dissociation constants were obtained by monitoring changes in chemical shifts as a function of ligand concentration. The changes in chemical shifts (...More data for this Ligand-Target Pair
TargetGTPase HRas [G12V,1-166]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Genetolead
US Patent
Genetolead
US Patent
Affinity DataKd: 5.18E+3nMAssay Description:Dissociation constants were obtained by monitoring changes in chemical shifts as a function of ligand concentration. The changes in chemical shifts (...More data for this Ligand-Target Pair
TargetGTPase HRas [G12V,1-166]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Genetolead
US Patent
Genetolead
US Patent
Affinity DataKd: 452nMAssay Description:SPR experiments were performed using the P4SPR from Affinité Instruments using Ni-NTA immobilization chips and his-tagged protein. Ni-NTA coated surf...More data for this Ligand-Target Pair
TargetGTPase HRas [G12V,1-166]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Genetolead
US Patent
Genetolead
US Patent
Affinity DataKd: 772nMAssay Description:MST experiments were performed with a Monolith NT.115 Pico (NanoTemper Technologies, Munich, Germany). Fluorescence labeling of GDP-HRasG12V was achi...More data for this Ligand-Target Pair
TargetGTPase HRas [G12V,1-166]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Genetolead
US Patent
Genetolead
US Patent
Affinity DataKd: <0nMAssay Description:Dissociation constants were obtained by monitoring changes in chemical shifts as a function of ligand concentration. The changes in chemical shifts (...More data for this Ligand-Target Pair
TargetGTPase HRas [G12V,1-166]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Genetolead
US Patent
Genetolead
US Patent
Affinity DataKd: 1.28E+3nMAssay Description:Dissociation constants were obtained by monitoring changes in chemical shifts as a function of ligand concentration. The changes in chemical shifts (...More data for this Ligand-Target Pair
TargetGTPase HRas [G12V,1-166]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Genetolead
US Patent
Genetolead
US Patent
Affinity DataKd: 3.19E+3nMAssay Description:Dissociation constants were obtained by monitoring changes in chemical shifts as a function of ligand concentration. The changes in chemical shifts (...More data for this Ligand-Target Pair
TargetGTPase HRas [G12V,1-166]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Genetolead
US Patent
Genetolead
US Patent
Affinity DataKd: 1.11E+4nMAssay Description:Dissociation constants were obtained by monitoring changes in chemical shifts as a function of ligand concentration. The changes in chemical shifts (...More data for this Ligand-Target Pair
TargetGTPase HRas [G12V,1-166]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Genetolead
US Patent
Genetolead
US Patent
Affinity DataKd: 6.43E+3nMAssay Description:Dissociation constants were obtained by monitoring changes in chemical shifts as a function of ligand concentration. The changes in chemical shifts (...More data for this Ligand-Target Pair
TargetGTPase HRas [G12V,1-166]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Genetolead
US Patent
Genetolead
US Patent
Affinity DataKd: 8.80E+4nMAssay Description:SPR experiments were performed using the P4SPR from Affinité Instruments using Ni-NTA immobilization chips and his-tagged protein. Ni-NTA coated surf...More data for this Ligand-Target Pair
TargetGTPase HRas [G12V,1-166]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Genetolead
US Patent
Genetolead
US Patent
Affinity DataKd: 3.10E+4nMAssay Description:ITC experiments were performed using a Nano ITC isothermal titration calorimeter from TA Instruments. Experiments were performed in reverse-mode by t...More data for this Ligand-Target Pair
TargetGTPase HRas [G12V,1-166]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Genetolead
US Patent
Genetolead
US Patent
Affinity DataKd: 7.40E+4nMAssay Description:MST experiments were performed with a Monolith NT.115 Pico (NanoTemper Technologies, Munich, Germany). Fluorescence labeling of GDP-HRasG12V was achi...More data for this Ligand-Target Pair
TargetGTPase HRas [G12V,1-166]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Genetolead
US Patent
Genetolead
US Patent
Affinity DataKd: 108nMAssay Description:Dissociation constants were obtained by monitoring changes in chemical shifts as a function of ligand concentration. The changes in chemical shifts (...More data for this Ligand-Target Pair
TargetGTPase HRas [G12V,1-166]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Genetolead
US Patent
Genetolead
US Patent
Affinity DataKd: 2.13E+4nMAssay Description:MST experiments were performed with a Monolith NT.115 Pico (NanoTemper Technologies, Munich, Germany). Fluorescence labeling of GDP-HRasG12V was achi...More data for this Ligand-Target Pair
TargetGTPase HRas [G12V,1-166]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Genetolead
US Patent
Genetolead
US Patent
Affinity DataKd: 2.51E+3nMAssay Description:Dissociation constants were obtained by monitoring changes in chemical shifts as a function of ligand concentration. The changes in chemical shifts (...More data for this Ligand-Target Pair
TargetGTPase HRas [G12V,1-166]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Genetolead
US Patent
Genetolead
US Patent
Affinity DataKd: 1.95E+6nMAssay Description:MST experiments were performed with a Monolith NT.115 Pico (NanoTemper Technologies, Munich, Germany). Fluorescence labeling of GDP-HRasG12V was achi...More data for this Ligand-Target Pair
TargetGTPase HRas [G12V,1-166]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Genetolead
US Patent
Genetolead
US Patent
Affinity DataKd: 3.18E+3nMAssay Description:Dissociation constants were obtained by monitoring changes in chemical shifts as a function of ligand concentration. The changes in chemical shifts (...More data for this Ligand-Target Pair
TargetGTPase HRas [G12V,1-166]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Genetolead
US Patent
Genetolead
US Patent
Affinity DataKd: 3.75E+3nMAssay Description:Dissociation constants were obtained by monitoring changes in chemical shifts as a function of ligand concentration. The changes in chemical shifts (...More data for this Ligand-Target Pair
TargetGTPase HRas [G12V,1-166]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Genetolead
US Patent
Genetolead
US Patent
Affinity DataKd: 1.53E+3nMAssay Description:Dissociation constants were obtained by monitoring changes in chemical shifts as a function of ligand concentration. The changes in chemical shifts (...More data for this Ligand-Target Pair
TargetGTPase HRas [G12V,1-166]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Genetolead
US Patent
Genetolead
US Patent
Affinity DataKd: 7.10E+3nMAssay Description:Dissociation constants were obtained by monitoring changes in chemical shifts as a function of ligand concentration. The changes in chemical shifts (...More data for this Ligand-Target Pair
TargetGTPase HRas [G12V,1-166]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Genetolead
US Patent
Genetolead
US Patent
Affinity DataKd: 6.77E+3nMAssay Description:Dissociation constants were obtained by monitoring changes in chemical shifts as a function of ligand concentration. The changes in chemical shifts (...More data for this Ligand-Target Pair
TargetGTPase HRas [G12V,1-166]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Genetolead
US Patent
Genetolead
US Patent
Affinity DataKd: 1.00E+4nMAssay Description:Dissociation constants were obtained by monitoring changes in chemical shifts as a function of ligand concentration. The changes in chemical shifts (...More data for this Ligand-Target Pair
TargetGTPase HRas [G12V,1-166]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Genetolead
US Patent
Genetolead
US Patent
Affinity DataKd: 7.40E+3nMAssay Description:Dissociation constants were obtained by monitoring changes in chemical shifts as a function of ligand concentration. The changes in chemical shifts (...More data for this Ligand-Target Pair
TargetGTPase HRas [G12V,1-166]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Genetolead
US Patent
Genetolead
US Patent
Affinity DataKd: 1.00E+4nMAssay Description:Dissociation constants were obtained by monitoring changes in chemical shifts as a function of ligand concentration. The changes in chemical shifts (...More data for this Ligand-Target Pair
TargetGTPase HRas [G12V,1-166]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Genetolead
US Patent
Genetolead
US Patent
Affinity DataKd: 6.00E+3nMAssay Description:Dissociation constants were obtained by monitoring changes in chemical shifts as a function of ligand concentration. The changes in chemical shifts (...More data for this Ligand-Target Pair
TargetGTPase HRas [G12V,1-166]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Genetolead
US Patent
Genetolead
US Patent
Affinity DataKd: 3.36E+3nMAssay Description:Dissociation constants were obtained by monitoring changes in chemical shifts as a function of ligand concentration. The changes in chemical shifts (...More data for this Ligand-Target Pair
TargetGTPase HRas [G12V,1-166]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Genetolead
US Patent
Genetolead
US Patent
Affinity DataKd: 2.32E+3nMAssay Description:Dissociation constants were obtained by monitoring changes in chemical shifts as a function of ligand concentration. The changes in chemical shifts (...More data for this Ligand-Target Pair
TargetGTPase HRas [G12V,1-166]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Genetolead
US Patent
Genetolead
US Patent
Affinity DataKd: 1.00E+4nMAssay Description:Dissociation constants were obtained by monitoring changes in chemical shifts as a function of ligand concentration. The changes in chemical shifts (...More data for this Ligand-Target Pair
TargetGTPase HRas [G12V,1-166]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Genetolead
US Patent
Genetolead
US Patent
Affinity DataKd: 6.28E+3nMAssay Description:Dissociation constants were obtained by monitoring changes in chemical shifts as a function of ligand concentration. The changes in chemical shifts (...More data for this Ligand-Target Pair
