Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 12157
TargetTyrosine-protein kinase JAK1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM683049(US20240209001, Example 7a | 1-(5-chloro-2-(difluor...)
Affinity DataIC50: 3.16nMAssay Description:The objective of this study was to assess the capability of compounds to inhibit all 4 JAK isoforms activity in a cell-free environment. Assay for JA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM683048(US20240209001, Example 6a | 1-(5-chloro-2-(difluor...)
Affinity DataIC50: 3.98nMAssay Description:The objective of this study was to assess the capability of compounds to inhibit all 4 JAK isoforms activity in a cell-free environment. Assay for JA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM683043(US20240209001, Example 1a | (1-(5-chloro-2-(difluo...)
Affinity DataIC50: 7.94nMAssay Description:The objective of this study was to assess the capability of compounds to inhibit all 4 JAK isoforms activity in a cell-free environment. Assay for JA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM683045(US20240209001, Example 3a | methyl 1-(5-chloro-2-(...)
Affinity DataIC50: 7.94nMAssay Description:The objective of this study was to assess the capability of compounds to inhibit all 4 JAK isoforms activity in a cell-free environment. Assay for JA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM683046(US20240209001, Example 4a | 2-(1-(5-chloro-2-(difl...)
Affinity DataIC50: 15.8nMAssay Description:The objective of this study was to assess the capability of compounds to inhibit all 4 JAK isoforms activity in a cell-free environment. Assay for JA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM683051(US20240209001, Example 9a | 1-(5-chloro-2-(difluor...)
Affinity DataIC50: 15.8nMAssay Description:The objective of this study was to assess the capability of compounds to inhibit all 4 JAK isoforms activity in a cell-free environment. Assay for JA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM683047(US20240209001, Example 5a | 2-(1-(5-chloro-2-(difl...)
Affinity DataIC50: 20nMAssay Description:The objective of this study was to assess the capability of compounds to inhibit all 4 JAK isoforms activity in a cell-free environment. Assay for JA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM683044(US20240209001, Example 2a | 2-(3-(5-chloro-2-(difl...)
Affinity DataIC50: 50.1nMAssay Description:The objective of this study was to assess the capability of compounds to inhibit all 4 JAK isoforms activity in a cell-free environment. Assay for JA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM683050(US20240209001, Example 8a | 1-(4-chloro-2-fluorobe...)
Affinity DataIC50: 200nMAssay Description:The objective of this study was to assess the capability of compounds to inhibit all 4 JAK isoforms activity in a cell-free environment. Assay for JA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM683052(US20240209001, Example 10a | 3-(3-(3-methyl-6-(pyr...)
Affinity DataIC50: 1.00E+3nMAssay Description:The objective of this study was to assess the capability of compounds to inhibit all 4 JAK isoforms activity in a cell-free environment. Assay for JA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent