Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 12042
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674436(US20240150370, Example 25)
Affinity DataIC50: 5.80E+3nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674435(US20240150370, Example 24)
Affinity DataIC50: 6.90E+3nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674431(US20240150370, Example 16)
Affinity DataIC50: 6.86E+4nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674459(rac-1-(5′-methyl-3′H-spiro[cyclopropan...)
Affinity DataIC50: 7.18E+4nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674451(1-[(2R,3S)-6-fluoro-2-methyl-2,3-dihydrofuro[3,2-b...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674443(rel-1-[(4S)-3,4-dihydro-2H-thiopyrano[3,2-b]pyridi...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674444(rel-1-[(3R)-2,3-dihydrothieno[3,2-b]pyridin-3-yl]m...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674445(rel-1-[(3S)-2,3-dihydrothieno[3,2-b]pyridin-3-yl]m...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674446(rel-1-[(2S,3R)-2-ethyl-2,3-dihydrofuro[3,2-b]pyrid...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674447(rac-1-(3,4-dihydro-2H-thiopyrano[3,2-b]pyridin-4-y...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674448(N-methyl-1-[(2R,3S)-2-methyl-2,3-dihydrofuro[3,2-b...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674449(US20240150370, Example 47)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674450(US20240150370, Example 48)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674441(1-[(2R,3S)-6-chloro-2-methyl-2,3-dihydrofuro[3,2-b...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674452(US20240150370, Example 50)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674453(US20240150370, Example 51)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674454(US20240150370, Example 58)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674455(US20240150370, Example 79)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674456(US20240150370, Example 83)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674457(US20240150370, Example 84)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674458(rac-1-(2-methoxy-5,6,7,8-tetrahydroquinolin-8-yl)m...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674460(rel-1-[(3'S)-3′H-spiro[cyclopropane-1,2̸...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674430(US20240150370, Example 15)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674422(N-methyl-1-[(2R,4S)-2-methyl-3,4-dihydro-2H-pyrano...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674423(US20240150370, Example 6)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674422(N-methyl-1-[(2R,4S)-2-methyl-3,4-dihydro-2H-pyrano...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674425(1-[(2R,3S)-6-fluoro-2-methyl-2,3-dihydrofuro[3,2-b...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674426(US20240150370, Example 9)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674427(US20240150370, Example 11)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674428(US20240150370, Example 12)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674429(US20240150370, Example 14)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674442(1-[(2R,3S)-5-chloro-2-methyl-2,3-dihydrofuro[3,2-b...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674432(US20240150370, Example 18)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674433(US20240150370, Example 22)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674434(US20240150370, Example 23)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674437(1-[(2R,3S)-2-methyl-2,3-dihydrofuro[3,2-b]pyridin-...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674438(US20240150370, Example 29)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674439(1-[(2R,3S)-2,7-dimethyl-2,3-dihydrofuro[3,2-b]pyri...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674440(1-[(2R,3S)-2,5-dimethyl-2,3-dihydrofuro[3,2-b]pyri...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674421(rac-1-[(3S,4S)-3-methyl-3,4-dihydro-2H-pyrano[3,2-...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent