Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 11938
TargetTyrosine-protein kinase BTK(Human)
Abbvie

US Patent
LigandPNGBDBM662949(US20240109877, Example 3)
Affinity DataIC50: 0.0340nMAssay Description:Btk kinase activity was measured in vitro using an electrophoretic mobility shift assay (MSA). The ability of Btk to phosphorylate a fluorescent pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Abbvie

US Patent
LigandPNGBDBM662958(US20240109877, Example 12)
Affinity DataIC50: 0.0360nMAssay Description:Btk kinase activity was measured in vitro using an electrophoretic mobility shift assay (MSA). The ability of Btk to phosphorylate a fluorescent pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Abbvie

US Patent
LigandPNGBDBM662952(US20240109877, Example 6)
Affinity DataIC50: 0.0400nMAssay Description:Btk kinase activity was measured in vitro using an electrophoretic mobility shift assay (MSA). The ability of Btk to phosphorylate a fluorescent pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Abbvie

US Patent
LigandPNGBDBM662960(US20240109877, Example 14)
Affinity DataIC50: 0.0530nMAssay Description:Btk kinase activity was measured in vitro using an electrophoretic mobility shift assay (MSA). The ability of Btk to phosphorylate a fluorescent pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Abbvie

US Patent
LigandPNGBDBM662954(US20240109877, Example 8)
Affinity DataIC50: 0.0800nMAssay Description:Btk kinase activity was measured in vitro using an electrophoretic mobility shift assay (MSA). The ability of Btk to phosphorylate a fluorescent pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Abbvie

US Patent
LigandPNGBDBM662957(US20240109877, Example 11)
Affinity DataIC50: 0.0970nMAssay Description:Btk kinase activity was measured in vitro using an electrophoretic mobility shift assay (MSA). The ability of Btk to phosphorylate a fluorescent pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Abbvie

US Patent
LigandPNGBDBM662947(US20240109877, Example 1)
Affinity DataIC50: 0.0980nMAssay Description:Btk kinase activity was measured in vitro using an electrophoretic mobility shift assay (MSA). The ability of Btk to phosphorylate a fluorescent pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Abbvie

US Patent
LigandPNGBDBM662953(US20240109877, Example 7)
Affinity DataIC50: 0.0980nMAssay Description:Btk kinase activity was measured in vitro using an electrophoretic mobility shift assay (MSA). The ability of Btk to phosphorylate a fluorescent pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Abbvie

US Patent
LigandPNGBDBM662961(US20240109877, Example 15)
Affinity DataIC50: 0.0990nMAssay Description:Btk kinase activity was measured in vitro using an electrophoretic mobility shift assay (MSA). The ability of Btk to phosphorylate a fluorescent pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Abbvie

US Patent
LigandPNGBDBM662955(US20240109877, Example 9)
Affinity DataIC50: 0.0990nMAssay Description:Btk kinase activity was measured in vitro using an electrophoretic mobility shift assay (MSA). The ability of Btk to phosphorylate a fluorescent pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Abbvie

US Patent
LigandPNGBDBM662965(US20240109877, Example 19)
Affinity DataIC50: 0.100nMAssay Description:Btk kinase activity was measured in vitro using an electrophoretic mobility shift assay (MSA). The ability of Btk to phosphorylate a fluorescent pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Abbvie

US Patent
LigandPNGBDBM662963(US20240109877, Example 17)
Affinity DataIC50: 0.103nMAssay Description:Btk kinase activity was measured in vitro using an electrophoretic mobility shift assay (MSA). The ability of Btk to phosphorylate a fluorescent pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Abbvie

US Patent
LigandPNGBDBM662956(US20240109877, Example 10)
Affinity DataIC50: 0.106nMAssay Description:Btk kinase activity was measured in vitro using an electrophoretic mobility shift assay (MSA). The ability of Btk to phosphorylate a fluorescent pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Abbvie

US Patent
LigandPNGBDBM662951(US20240109877, Example 5)
Affinity DataIC50: 0.113nMAssay Description:Btk kinase activity was measured in vitro using an electrophoretic mobility shift assay (MSA). The ability of Btk to phosphorylate a fluorescent pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Abbvie

US Patent
LigandPNGBDBM662948(US20240109877, Example 2)
Affinity DataIC50: 0.128nMAssay Description:Btk kinase activity was measured in vitro using an electrophoretic mobility shift assay (MSA). The ability of Btk to phosphorylate a fluorescent pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Abbvie

US Patent
LigandPNGBDBM662959(US20240109877, Example 13)
Affinity DataIC50: 0.140nMAssay Description:Btk kinase activity was measured in vitro using an electrophoretic mobility shift assay (MSA). The ability of Btk to phosphorylate a fluorescent pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Abbvie

US Patent
LigandPNGBDBM662950(US20240109877, Example 4)
Affinity DataIC50: 0.141nMAssay Description:Btk kinase activity was measured in vitro using an electrophoretic mobility shift assay (MSA). The ability of Btk to phosphorylate a fluorescent pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Abbvie

US Patent
LigandPNGBDBM662962(US20240109877, Example 16)
Affinity DataIC50: 0.438nMAssay Description:Btk kinase activity was measured in vitro using an electrophoretic mobility shift assay (MSA). The ability of Btk to phosphorylate a fluorescent pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Abbvie

US Patent
LigandPNGBDBM662964(US20240109877, Example 18)
Affinity DataIC50: 0.496nMAssay Description:Btk kinase activity was measured in vitro using an electrophoretic mobility shift assay (MSA). The ability of Btk to phosphorylate a fluorescent pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
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TargetProtein cereblon(Human)
Abbvie

US Patent
LigandPNGBDBM662952(US20240109877, Example 6)
Affinity DataIC50: 378nMAssay Description:Competition Assay: Test compounds in 100% dimethyl sulfoxide were plated onto white, low volume 384 well plates (PerkinElmer Proxiplate 384 plus # 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
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TargetProtein cereblon(Human)
Abbvie

US Patent
LigandPNGBDBM662953(US20240109877, Example 7)
Affinity DataIC50: 609nMAssay Description:Competition Assay: Test compounds in 100% dimethyl sulfoxide were plated onto white, low volume 384 well plates (PerkinElmer Proxiplate 384 plus # 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
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TargetProtein cereblon(Human)
Abbvie

US Patent
LigandPNGBDBM662951(US20240109877, Example 5)
Affinity DataIC50: 648nMAssay Description:Competition Assay: Test compounds in 100% dimethyl sulfoxide were plated onto white, low volume 384 well plates (PerkinElmer Proxiplate 384 plus # 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
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TargetProtein cereblon(Human)
Abbvie

US Patent
LigandPNGBDBM662955(US20240109877, Example 9)
Affinity DataIC50: 658nMAssay Description:Competition Assay: Test compounds in 100% dimethyl sulfoxide were plated onto white, low volume 384 well plates (PerkinElmer Proxiplate 384 plus # 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
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TargetProtein cereblon(Human)
Abbvie

US Patent
LigandPNGBDBM662948(US20240109877, Example 2)
Affinity DataIC50: 749nMAssay Description:Competition Assay: Test compounds in 100% dimethyl sulfoxide were plated onto white, low volume 384 well plates (PerkinElmer Proxiplate 384 plus # 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
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TargetProtein cereblon(Human)
Abbvie

US Patent
LigandPNGBDBM662964(US20240109877, Example 18)
Affinity DataIC50: 1.25E+3nMAssay Description:Competition Assay: Test compounds in 100% dimethyl sulfoxide were plated onto white, low volume 384 well plates (PerkinElmer Proxiplate 384 plus # 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
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TargetProtein cereblon(Human)
Abbvie

US Patent
LigandPNGBDBM662947(US20240109877, Example 1)
Affinity DataIC50: 1.26E+3nMAssay Description:Competition Assay: Test compounds in 100% dimethyl sulfoxide were plated onto white, low volume 384 well plates (PerkinElmer Proxiplate 384 plus # 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
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TargetProtein cereblon(Human)
Abbvie

US Patent
LigandPNGBDBM662958(US20240109877, Example 12)
Affinity DataIC50: 2.01E+3nMAssay Description:Competition Assay: Test compounds in 100% dimethyl sulfoxide were plated onto white, low volume 384 well plates (PerkinElmer Proxiplate 384 plus # 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
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TargetProtein cereblon(Human)
Abbvie

US Patent
LigandPNGBDBM662957(US20240109877, Example 11)
Affinity DataIC50: 2.15E+3nMAssay Description:Competition Assay: Test compounds in 100% dimethyl sulfoxide were plated onto white, low volume 384 well plates (PerkinElmer Proxiplate 384 plus # 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
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TargetProtein cereblon(Human)
Abbvie

US Patent
LigandPNGBDBM662960(US20240109877, Example 14)
Affinity DataIC50: 2.33E+3nMAssay Description:Competition Assay: Test compounds in 100% dimethyl sulfoxide were plated onto white, low volume 384 well plates (PerkinElmer Proxiplate 384 plus # 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
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TargetProtein cereblon(Human)
Abbvie

US Patent
LigandPNGBDBM662954(US20240109877, Example 8)
Affinity DataIC50: 3.38E+3nMAssay Description:Competition Assay: Test compounds in 100% dimethyl sulfoxide were plated onto white, low volume 384 well plates (PerkinElmer Proxiplate 384 plus # 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
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TargetProtein cereblon(Human)
Abbvie

US Patent
LigandPNGBDBM662963(US20240109877, Example 17)
Affinity DataIC50: 3.87E+3nMAssay Description:Competition Assay: Test compounds in 100% dimethyl sulfoxide were plated onto white, low volume 384 well plates (PerkinElmer Proxiplate 384 plus # 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
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TargetProtein cereblon(Human)
Abbvie

US Patent
LigandPNGBDBM662956(US20240109877, Example 10)
Affinity DataIC50: 6.31E+3nMAssay Description:Competition Assay: Test compounds in 100% dimethyl sulfoxide were plated onto white, low volume 384 well plates (PerkinElmer Proxiplate 384 plus # 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
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TargetProtein cereblon(Human)
Abbvie

US Patent
LigandPNGBDBM662949(US20240109877, Example 3)
Affinity DataIC50: 9.57E+3nMAssay Description:Competition Assay: Test compounds in 100% dimethyl sulfoxide were plated onto white, low volume 384 well plates (PerkinElmer Proxiplate 384 plus # 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Abbvie

US Patent
LigandPNGBDBM662962(US20240109877, Example 16)
Affinity DataIC50: 1.00E+4nMAssay Description:Competition Assay: Test compounds in 100% dimethyl sulfoxide were plated onto white, low volume 384 well plates (PerkinElmer Proxiplate 384 plus # 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Abbvie

US Patent
LigandPNGBDBM662961(US20240109877, Example 15)
Affinity DataIC50: 1.00E+4nMAssay Description:Competition Assay: Test compounds in 100% dimethyl sulfoxide were plated onto white, low volume 384 well plates (PerkinElmer Proxiplate 384 plus # 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Abbvie

US Patent
LigandPNGBDBM662959(US20240109877, Example 13)
Affinity DataIC50: 1.00E+4nMAssay Description:Competition Assay: Test compounds in 100% dimethyl sulfoxide were plated onto white, low volume 384 well plates (PerkinElmer Proxiplate 384 plus # 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Abbvie

US Patent
LigandPNGBDBM662950(US20240109877, Example 4)
Affinity DataIC50: 1.00E+4nMAssay Description:Competition Assay: Test compounds in 100% dimethyl sulfoxide were plated onto white, low volume 384 well plates (PerkinElmer Proxiplate 384 plus # 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Abbvie

US Patent
LigandPNGBDBM662965(US20240109877, Example 19)
Affinity DataIC50: 1.00E+4nMAssay Description:Competition Assay: Test compounds in 100% dimethyl sulfoxide were plated onto white, low volume 384 well plates (PerkinElmer Proxiplate 384 plus # 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent