Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 10955
LigandPNGBDBM580944(US11492357, Compound)
Affinity DataIC50: 21nMAssay Description:ormula (I) bis-hydrochloride salt prepared in Example 2 (hereinafter referred to as Compound⋅2HCl ) was tested for inhibitory activity against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM580944(US11492357, Compound)
Affinity DataIC50: 30nMAssay Description:ormula (I) bis-hydrochloride salt prepared in Example 2 (hereinafter referred to as Compound⋅2HCl ) was tested for inhibitory activity against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM50396483(PLX-4032 | RG 7204 | Ro 5185426 | VEMURAFENIB | US...)
Affinity DataIC50: 107nMAssay Description:ormula (I) bis-hydrochloride salt prepared in Example 2 (hereinafter referred to as Compound⋅2HCl ) was tested for inhibitory activity against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM50396483(PLX-4032 | RG 7204 | Ro 5185426 | VEMURAFENIB | US...)
Affinity DataIC50: 111nMAssay Description:ormula (I) bis-hydrochloride salt prepared in Example 2 (hereinafter referred to as Compound⋅2HCl ) was tested for inhibitory activity against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent

LigandPNGBDBM50396483(PLX-4032 | RG 7204 | Ro 5185426 | VEMURAFENIB | US...)
Affinity DataIC50: 138nMAssay Description:ormula (I) bis-hydrochloride salt prepared in Example 2 (hereinafter referred to as Compound⋅2HCl ) was tested for inhibitory activity against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM580944(US11492357, Compound)
Affinity DataIC50: 392nMAssay Description:ormula (I) bis-hydrochloride salt prepared in Example 2 (hereinafter referred to as Compound⋅2HCl ) was tested for inhibitory activity against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent