Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 10751
TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563488((S)-2-amino-3-(4-(4- ((R)-1-(4-chloro-2-(3- meth...)
Affinity DataIC50: 36nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
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TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563506(US11407763, Example 67 | (2S)-2-amino-3-(4-(2- ami...)
Affinity DataIC50: 91nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
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TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563495(US11407763, Example 45 | (2S)-2-amino-3-(4-(2- am...)
Affinity DataIC50: 98nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
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TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563495(US11407763, Example 45 | (2S)-2-amino-3-(4-(2- am...)
Affinity DataIC50: 114nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
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TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563506(US11407763, Example 67 | (2S)-2-amino-3-(4-(2- ami...)
Affinity DataIC50: 125nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
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TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563512(8-(2-amino-6-((R)-1-(4- chloro-2-(3-methyl-1H- pyr...)
Affinity DataIC50: 185nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
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TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563512(8-(2-amino-6-((R)-1-(4- chloro-2-(3-methyl-1H- pyr...)
Affinity DataIC50: 194nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
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TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563497(US11407763, Example 58 | (2S)-2-amino-3-(4-(2- am...)
Affinity DataIC50: 204nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
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TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563536((S)-2-amino-3-(4-(2- amino-4-((R)-1-(4- chloro-2-(...)
Affinity DataIC50: 208nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
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TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563541(8-(2-amino-6-((R)-1-(4- chloro-2-(5,6-dihydro- 2H-...)
Affinity DataIC50: 209nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
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TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563509((S)-2-amino-3-(4-(4- ((R)-1-(4-chloro-2- (5,6-dihy...)
Affinity DataIC50: 263nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
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TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563497(US11407763, Example 58 | (2S)-2-amino-3-(4-(2- am...)
Affinity DataIC50: 281nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
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TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563489((S)-2-amino-3-(4-(2- amino-7-((3'-methoxy- [1,1'...)
Affinity DataIC50: 297nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
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TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563526(8-(4-((R)-1-(4-chloro- 2-(3-methyl-1H- pyrazole-1-...)
Affinity DataIC50: 307nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
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TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563509((S)-2-amino-3-(4-(4- ((R)-1-(4-chloro-2- (5,6-dihy...)
Affinity DataIC50: 371nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
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TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563531(US11407763, Example 89 | 8-(2-amino-6-((R)- 2,2,2-...)
Affinity DataIC50: 409nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
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TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563502((2S)-2-amino-3-(4-(2- amino-6-(1-(5-chloro- [1,1'-...)
Affinity DataIC50: 433nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
Go to US Patent

TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563511((2S)-2-amino-3-(4-(2- amino-6-((R)-1-(5- chloro-4'...)
Affinity DataIC50: 443nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
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TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563492((S)-2-amino-3-(4-(4- ((R)-1-(5-chloro-3'- fluoro...)
Affinity DataIC50: 565nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
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TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563491((S)-2-amino-3-(4-(7- ((3'-methoxy-[1,1'- bipheny...)
Affinity DataIC50: 578nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
Go to US Patent

TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563493((2S)-2-amino-3-(4-(4- (1-(5-chloro-[1,1'- biphen...)
Affinity DataIC50: 679nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
Go to US Patent

TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563531(US11407763, Example 89 | 8-(2-amino-6-((R)- 2,2,2-...)
Affinity DataIC50: 741nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
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TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563529((2S)-2-amino-3-(4-(2- amino-6-((R)-1-(4- chloro-2-...)
Affinity DataIC50: 940nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
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TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563490(ethyl (S)-2-amino-3-(4- (4-((R)-1-(4-chloro-2- (...)
Affinity DataIC50: 993nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
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TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563515(8-(2-amino-6-((R)-1-(4- chloro-2-(3,6-dihydro- 2H-...)
Affinity DataIC50: 1.15E+3nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
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TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563494((2S)-2-amino-3-(4-(4- ((R)-1-(4-chloro-2-(3- met...)
Affinity DataIC50: 1.51E+3nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
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TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563496((2S)-2-amino-3-(4-(6- ((R)-1-(4-chloro-2-(3- met...)
Affinity DataIC50: 1.82E+3nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
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TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563500((2S)-2-amino-3-(4-(4- (1-(5-chloro-4'-fluoro- [1,1...)
Affinity DataIC50: 8.72E+3nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
Go to US Patent