Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 10343
TargetRho-associated protein kinase 2(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM14027(AT877 | CHEMBL38380 | 5-(1,4-diazepan-1-ylsulfonyl...)
Affinity DataKd:  45nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetRho-associated protein kinase 2(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM528673(US11198680, Compound Racemic-BA-1049-Lot-2)
Affinity DataKd:  46nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM14027(AT877 | CHEMBL38380 | 5-(1,4-diazepan-1-ylsulfonyl...)
Affinity DataKd:  50nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetRho-associated protein kinase 1(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM528673(US11198680, Compound Racemic-BA-1049-Lot-2)
Affinity DataKd:  54nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM322155(US11311541, Example SLx-2119 | US10696660, SLx-211...)
Affinity DataKd:  65nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM528673(US11198680, Compound Racemic-BA-1049-Lot-2)
Affinity DataKd:  66nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM528673(US11198680, Compound Racemic-BA-1049-Lot-2)
Affinity DataKd:  89nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM529432(US11198680, Compound BS-1050)
Affinity DataKd:  150nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM163433(US9687483, 1 | BA-1049 | US11198680, Compound BA 1...)
Affinity DataKd:  155nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM529432(US11198680, Compound BS-1050)
Affinity DataKd:  160nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM163433(US9687483, 1 | BA-1049 | US11198680, Compound BA 1...)
Affinity DataKd:  160nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM529433(US11198680, Compound BS-1050A)
Affinity DataKd:  190nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM529433(US11198680, Compound BS-1050A)
Affinity DataKd:  210nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM529431(US11198680, Compound BS-1043)
Affinity DataKd:  230nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM163433(US9687483, 1 | BA-1049 | US11198680, Compound BA 1...)
Affinity DataIC50: 240nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM529431(US11198680, Compound BS-1043)
Affinity DataKd:  270nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM529430(US11198680, Compound BS-1042)
Affinity DataKd:  280nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM529434(US11198680, Compound BS-1050B)
Affinity DataKd:  280nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM163433(US9687483, 1 | BA-1049 | US11198680, Compound BA 1...)
Affinity DataIC50: 340nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 15 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM163433(US9687483, 1 | BA-1049 | US11198680, Compound BA 1...)
Affinity DataIC50: 340nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 15 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM528675(US11198680, Compound BA 1049B)
Affinity DataIC50: 340nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM529430(US11198680, Compound BS-1042)
Affinity DataKd:  370nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM529434(US11198680, Compound BS-1050B)
Affinity DataKd:  370nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM528673(US11198680, Compound Racemic-BA-1049-Lot-2)
Affinity DataIC50: 600nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM528675(US11198680, Compound BA 1049B)
Affinity DataIC50: 690nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM528674(US11198680, Compound BA 1049A)
Affinity DataIC50: 720nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM528670(US11198680, Compound BA 1049 (S))
Affinity DataIC50: 730nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM529429(US11198680, Compound BS-1041)
Affinity DataKd:  760nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM529429(US11198680, Compound BS-1041)
Affinity DataKd:  800nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM528670(US11198680, Compound BA 1049 (S))
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 15 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM528670(US11198680, Compound BA 1049 (S))
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 15 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM528673(US11198680, Compound Racemic-BA-1049-Lot-2)
Affinity DataIC50: 1.02E+3nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM528673(US11198680, Compound Racemic-BA-1049-Lot-2)
Affinity DataIC50: 1.02E+3nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM528673(US11198680, Compound Racemic-BA-1049-Lot-2)
Affinity DataIC50: 1.28E+3nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM528674(US11198680, Compound BA 1049A)
Affinity DataIC50: 1.44E+3nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM163433(US9687483, 1 | BA-1049 | US11198680, Compound BA 1...)
Affinity DataIC50: 3.90E+3nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM322155(US11311541, Example SLx-2119 | US10696660, SLx-211...)
Affinity DataKd:  7.40E+3nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM528670(US11198680, Compound BA 1049 (S))
Affinity DataIC50: 1.02E+4nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM163433(US9687483, 1 | BA-1049 | US11198680, Compound BA 1...)
Affinity DataIC50: 2.96E+4nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 70 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM163433(US9687483, 1 | BA-1049 | US11198680, Compound BA 1...)
Affinity DataIC50: 2.96E+4nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 70 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM528670(US11198680, Compound BA 1049 (S))
Affinity DataIC50: 5.79E+4nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 70 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Bioaxone Biosciences

US Patent
LigandPNGBDBM528670(US11198680, Compound BA 1049 (S))
Affinity DataIC50: 5.79E+4nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 70 uM. The hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2022
Entry Details
US Patent