Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50036481
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50057482(ONO-3805 | 4-(2-{4-[(S)-1-(4-Isobutyl-phenyl)-etho...)
Affinity DataIC50: 180nMAssay Description:Compound was tested in vitro for inhibitory activity against type 1 5-alpha reductase Isozyme homogenated from rat epididymisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50032297(4-[2-((E)-3-{1-[Bis-(4-fluoro-phenyl)-methyl]-1H-i...)
Affinity DataIC50: 210nMAssay Description:Compound was tested in vitro for inhibitory activity against type 2 5-alpha reductase isozyme homogenated from rat epididymisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50055150(4-[2-((E)-3-{1-[Bis-(4-fluoro-phenyl)-methyl]-1H-i...)
Affinity DataIC50: 280nMAssay Description:Compound was tested in vitro for inhibitory activity against type 2 5-alpha reductase Isozyme homogenated from rat epididymisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50055148(4-(2-{(E)-3-[1-(1-Propyl-butyl)-1H-indol-5-yl]-pen...)
Affinity DataIC50: 750nMAssay Description:Compound was tested in vitro for inhibitory activity against type 2 5-alpha reductase Isozyme homogenated from rat epididymisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50334788((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...)
Affinity DataIC50: 2.10E+3nMAssay Description:Compound was tested in vitro for inhibitory activity against type 2 5-alpha reductase Isozyme homogenated from rat epididymisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50032282(4-(2-{(E)-3-[1-(1-Propyl-butyl)-1H-indol-5-yl]-but...)
Affinity DataIC50: 2.30E+3nMAssay Description:5 alpha- reductase inhibitory activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50055147(4-{2-[(E)-3-(1-Benzhydryl-1H-indol-5-yl)-pent-2-en...)
Affinity DataIC50: 2.50E+3nMAssay Description:5 alpha- reductase inhibitory activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50055149(4-[2-((E)-3-{1-[Bis-(4-fluoro-phenyl)-methyl]-1H-i...)
Affinity DataIC50: 3.40E+3nMAssay Description:5 alpha- reductase inhibitory activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50055154(4-(2-{(E)-3-[1-(1-Propyl-pentyl)-1H-indol-5-yl]-pe...)
Affinity DataIC50: 3.60E+3nMAssay Description:5 alpha- reductase inhibitory activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50032281(4-(2-{(E)-3-[1-(1-Propyl-pentyl)-1H-indol-5-yl]-bu...)
Affinity DataIC50: 4.10E+3nMAssay Description:5 alpha- reductase inhibitory activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50055146(4-(2-{(E)-3-[1-(1-Isobutyl-3-methyl-butyl)-1H-indo...)
Affinity DataIC50: 4.80E+3nMAssay Description:5 alpha- reductase inhibitory activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50055152(4-[2-((E)-3-{1-[Bis-(4-fluoro-phenyl)-methyl]-1H-i...)
Affinity DataIC50: 4.90E+3nMAssay Description:5 alpha- reductase inhibitory activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50032288(4-{2-[(E)-3-(1-Benzhydryl-1H-indol-5-yl)-but-2-eno...)
Affinity DataIC50: 5.60E+3nMAssay Description:5 alpha- reductase inhibitory activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50032264(4-(2-{(E)-3-[1-(1-Isobutyl-3-methyl-butyl)-1H-indo...)
Affinity DataIC50: 8.00E+3nMAssay Description:5 alpha- reductase inhibitory activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50032315(4-{2-[(E)-3-(1-Benzyl-1H-indol-5-yl)-but-2-enoylam...)
Affinity DataIC50: 5.00E+4nMAssay Description:5 alpha- reductase inhibitory activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50055145(4-[2-((Z)-3-{1-[Bis-(4-fluoro-phenyl)-methyl]-1H-i...)
Affinity DataIC50: 1.00E+5nMAssay Description:5 alpha- reductase inhibitory activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50055153(4-{2-[(E)-3-(1-Benzyl-1H-indol-5-yl)-2-methyl-acry...)
Affinity DataIC50: 1.20E+5nMAssay Description:5 alpha- reductase inhibitory activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50055151(4-{2-[(E)-3-(1-Benzyl-1H-indol-5-yl)-acryloylamino...)
Affinity DataIC50: 1.70E+6nMAssay Description:5 alpha- reductase inhibitory activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed