Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50036441
TargetMetabotropic glutamate receptor 2(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM17657(L-Glutamic acid | L-Glu | (2S)-2-aminopentanedioic...)
Affinity DataEC50:  8.50E+3nMAssay Description:Agonistic activity at mGlu2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM17657(L-Glutamic acid | L-Glu | (2S)-2-aminopentanedioic...)
Affinity DataEC50:  1.50E+4nMAssay Description:Agonistic activity at mGlu4a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM17657(L-Glutamic acid | L-Glu | (2S)-2-aminopentanedioic...)
Affinity DataEC50:  1.90E+4nMAssay Description:Agonistic activity at mGlu1-alpha receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM17657(L-Glutamic acid | L-Glu | (2S)-2-aminopentanedioic...)
Affinity DataEC50:  2.00E+4nMAssay Description:Agonistic activity at mGlu6 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052553((2S)-2-aminohexanedioic acid | L-2-aminoadipic aci...)
Affinity DataEC50:  3.50E+4nMAssay Description:Agonistic activity at mGlu2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052551(2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-butyr...)
Affinity DataEC50:  8.20E+4nMAssay Description:Agonistic activity at mGlu6 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM17662(CHEMBL276815 | 2-amino-3-(3-hydroxy-5-methyl-4-iso...)
Affinity DataIC50: 1.00E+5nMAssay Description:The compound was evaluated for agonist to competitive inhibition of radioligand ([3H]- CPP ) at Ionotropic Excitatory Amino acid receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052553((2S)-2-aminohexanedioic acid | L-2-aminoadipic aci...)
Affinity DataEC50:  1.40E+5nMAssay Description:Agonistic activity at mGlu6 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM17662(CHEMBL276815 | 2-amino-3-(3-hydroxy-5-methyl-4-iso...)
Affinity DataEC50:  2.20E+5nMAssay Description:Agonist activity of the compound at Metabotropic Excitatory Amino acid Receptors Expressed in CHO cells. mGlu6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052555(2-Amino-5-(3-hydroxy-5-methyl-isoxazol-4-yl)-penta...)
Affinity DataEC50:  4.10E+5nMAssay Description:Agonistic activity at mGlu6 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004852(CHEMBL280585 | AMAA | Amino-(3-hydroxy-5-methyl-is...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity of the compound at Metabotropic Excitatory Amino acid Receptors Expressed in CHO cells. mGlu1-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM85356(CAS_542-32-5 | (S)-2-Aminoadipic acid)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonistic activity at mGlu6 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | D-Glu | D-Glutamat...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonistic activity at mGlu6 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052549(2-Amino-heptanedioic acid | CHEMBL111050)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonistic activity at mGlu1-alpha receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50026947(2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propi...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity of the compound at Metabotropic Excitatory Amino acid Receptors Expressed in CHO cells. mGlu2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052549(2-Amino-heptanedioic acid | CHEMBL111050)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonistic activity at mGlu6 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052554(2-Amino-6-(3-hydroxy-5-methyl-isoxazol-4-yl)-hexan...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonistic activity at mGlu1-alpha receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM85356(CAS_542-32-5 | (S)-2-Aminoadipic acid)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonistic activity at mGlu1-alpha receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004852(CHEMBL280585 | AMAA | Amino-(3-hydroxy-5-methyl-is...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity of the compound at Metabotropic Excitatory Amino acid Receptors Expressed in CHO cells. mGlu2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052555(2-Amino-5-(3-hydroxy-5-methyl-isoxazol-4-yl)-penta...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonistic activity at mGlu2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052554(2-Amino-6-(3-hydroxy-5-methyl-isoxazol-4-yl)-hexan...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonistic activity at mGlu2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | D-Glu | D-Glutamat...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonistic activity at mGlu2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052552(2-Amino-octanedioic acid | CHEMBL320957)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonistic activity at mGlu6 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052555(2-Amino-5-(3-hydroxy-5-methyl-isoxazol-4-yl)-penta...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonistic activity at mGlu1-alpha receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052554(2-Amino-6-(3-hydroxy-5-methyl-isoxazol-4-yl)-hexan...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonistic activity at mGlu6 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50026947(2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propi...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity of the compound at Metabotropic Excitatory Amino acid Receptors Expressed in CHO cells. mGlu6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM17662(CHEMBL276815 | 2-amino-3-(3-hydroxy-5-methyl-4-iso...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity of the compound at Metabotropic Excitatory Amino acid Receptors Expressed in CHO cells. mGlu2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052552(2-Amino-octanedioic acid | CHEMBL320957)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonistic activity at mGlu2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM31174(CHEMBL29757 | D-Aspartate | D-Aspartic Acid)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonistic activity at mGlu1-alpha receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM17662(CHEMBL276815 | 2-amino-3-(3-hydroxy-5-methyl-4-iso...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity of the compound at Metabotropic Excitatory Amino acid Receptors Expressed in CHO cells. mGlu1-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052553((2S)-2-aminohexanedioic acid | L-2-aminoadipic aci...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonistic activity at mGlu1-alpha receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM18125(L-Aspartic acid, 2 | L-Aspartate | CHEMBL274323 | ...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonistic activity at mGlu2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM18125(L-Aspartic acid, 2 | L-Aspartate | CHEMBL274323 | ...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonistic activity at mGlu6 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM31174(CHEMBL29757 | D-Aspartate | D-Aspartic Acid)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonistic activity at mGlu6 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052549(2-Amino-heptanedioic acid | CHEMBL111050)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonistic activity at mGlu2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50026947(2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propi...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity of the compound at Metabotropic Excitatory Amino acid Receptors Expressed in CHO cells. mGlu1-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004852(CHEMBL280585 | AMAA | Amino-(3-hydroxy-5-methyl-is...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity of the compound at Metabotropic Excitatory Amino acid Receptors Expressed in CHO cells. mGlu6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM31174(CHEMBL29757 | D-Aspartate | D-Aspartic Acid)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonistic activity at mGlu2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM85356(CAS_542-32-5 | (S)-2-Aminoadipic acid)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonistic activity at mGlu2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | D-Glu | D-Glutamat...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonistic activity at mGlu1-alpha receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM18125(L-Aspartic acid, 2 | L-Aspartate | CHEMBL274323 | ...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonistic activity at mGlu1-alpha receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052552(2-Amino-octanedioic acid | CHEMBL320957)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonistic activity at mGlu1-alpha receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052551(2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-butyr...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonistic activity at mGlu2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052551(2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-butyr...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonistic activity at mGlu1-alpha receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052553((2S)-2-aminohexanedioic acid | L-2-aminoadipic aci...)
Affinity DataEC50: >3.00E+6nMAssay Description:Agonistic activity at mGlu4a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052551(2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-butyr...)
Affinity DataEC50: >3.00E+6nMAssay Description:Agonistic activity at mGlu4a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052555(2-Amino-5-(3-hydroxy-5-methyl-isoxazol-4-yl)-penta...)
Affinity DataEC50: >3.00E+6nMAssay Description:Agonistic activity at mGlu4a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM17662(CHEMBL276815 | 2-amino-3-(3-hydroxy-5-methyl-4-iso...)
Affinity DataEC50: >3.00E+6nMAssay Description:Agonist activity of the compound at Metabotropic Excitatory Amino acid Receptors Expressed in CHO cells. mGlu4aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed