Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50036270
TargetThromboxane-A synthase(Rat)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037039(2-Amino-5,7-dimethyl-4-pyridin-3-ylmethyl-benzothi...)
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037037(5,7-Dimethyl-2-methylamino-4-pyridin-3-ylmethyl-be...)
Affinity DataIC50: 9nMAssay Description:Tested for inhibitory activity against thromboxane A2 (TXA2) synthetase in microsome of human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037040(2-Ethylamino-5,7-dimethyl-4-pyridin-3-ylmethyl-ben...)
Affinity DataIC50: 10nMAssay Description:Tested for inhibitory activity against thromboxane A2 (TXA2) synthetase in microsome of human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037044(4-[(6-Hydroxy-4,5,7-trimethyl-benzothiazol-2-ylami...)
Affinity DataIC50: 30nMAssay Description:Tested for inhibitory activity against leukotriene B4 (LTB4) receptor in human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
LigandPNGBDBM50037036(5,7-Dimethoxy-2-[(pyridin-3-ylmethyl)-amino]-benzo...)
Affinity DataIC50: 90nMAssay Description:Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetThromboxane-A synthase(Rat)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037051(5,7-Dimethyl-2-propylamino-4-pyridin-3-ylmethyl-be...)
Affinity DataIC50: 90nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetThromboxane-A synthase(Rat)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037037(5,7-Dimethyl-2-methylamino-4-pyridin-3-ylmethyl-be...)
Affinity DataIC50: 90nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetThromboxane-A synthase(Rat)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037040(2-Ethylamino-5,7-dimethyl-4-pyridin-3-ylmethyl-ben...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
LigandPNGBDBM50037037(5,7-Dimethyl-2-methylamino-4-pyridin-3-ylmethyl-be...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetThromboxane-A synthase(Rat)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037046(2-Amino-5-methoxy-7-methyl-4-pyridin-3-ylmethyl-be...)
Affinity DataIC50: 110nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
LigandPNGBDBM50037041(2-Amino-7-ethyl-5-methoxy-4-pyridin-3-ylmethyl-ben...)
Affinity DataIC50: 150nMAssay Description:Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
LigandPNGBDBM50037045(5-Methoxy-7-methyl-2-methylamino-4-pyridin-3-ylmet...)
Affinity DataIC50: 170nMAssay Description:Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
LigandPNGBDBM50037046(2-Amino-5-methoxy-7-methyl-4-pyridin-3-ylmethyl-be...)
Affinity DataIC50: 170nMAssay Description:Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetThromboxane-A synthase(Rat)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037041(2-Amino-7-ethyl-5-methoxy-4-pyridin-3-ylmethyl-ben...)
Affinity DataIC50: 180nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
LigandPNGBDBM50037039(2-Amino-5,7-dimethyl-4-pyridin-3-ylmethyl-benzothi...)
Affinity DataIC50: 190nMAssay Description:Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
LigandPNGBDBM50037044(4-[(6-Hydroxy-4,5,7-trimethyl-benzothiazol-2-ylami...)
Affinity DataIC50: 210nMAssay Description:Tested for inhibitory activity against 5-lipoxygenase in microsome of RBL-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037037(5,7-Dimethyl-2-methylamino-4-pyridin-3-ylmethyl-be...)
Affinity DataIC50: 210nMAssay Description:Tested for inhibitory activity against leukotriene B4 (LTB4) receptor in human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
LigandPNGBDBM50037037(5,7-Dimethyl-2-methylamino-4-pyridin-3-ylmethyl-be...)
Affinity DataIC50: 230nMAssay Description:Tested for inhibitory activity against 5-lipoxygenase in microsome of RBL-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
LigandPNGBDBM50037038(2-Ethylamino-4,7-dimethyl-5-pyridin-3-ylmethyl-ben...)
Affinity DataIC50: 230nMAssay Description:Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
LigandPNGBDBM50037047(2-Amino-4,5-dimethyl-7-pyridin-3-ylmethyl-benzothi...)
Affinity DataIC50: 250nMAssay Description:Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
LigandPNGBDBM50037043(2-Ethylamino-4,5-dimethyl-7-pyridin-3-ylmethyl-ben...)
Affinity DataIC50: 270nMAssay Description:Tested for inhibitory activity against 5-lipoxygenase in microsome of RBL-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
LigandPNGBDBM50037053(4,7-Dimethyl-2-methylamino-5-pyridin-3-ylmethyl-be...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetThromboxane-A synthase(Rat)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037048(7-Ethyl-5-methoxy-2-methylamino-4-pyridin-3-ylmeth...)
Affinity DataIC50: 330nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037038(2-Ethylamino-4,7-dimethyl-5-pyridin-3-ylmethyl-ben...)
Affinity DataIC50: 390nMAssay Description:Tested for inhibitory activity against thromboxane A2 (TXA2) synthetase in microsome of human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetThromboxane-A synthase(Rat)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037038(2-Ethylamino-4,7-dimethyl-5-pyridin-3-ylmethyl-ben...)
Affinity DataIC50: 650nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037043(2-Ethylamino-4,5-dimethyl-7-pyridin-3-ylmethyl-ben...)
Affinity DataIC50: 810nMAssay Description:Tested for inhibitory activity against thromboxane A2 (TXA2) synthetase in microsome of human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
LigandPNGBDBM50037040(2-Ethylamino-5,7-dimethyl-4-pyridin-3-ylmethyl-ben...)
Affinity DataIC50: 910nMAssay Description:Tested for inhibitory activity against 5-lipoxygenase in microsome of RBL-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetThromboxane-A synthase(Rat)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037045(5-Methoxy-7-methyl-2-methylamino-4-pyridin-3-ylmet...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetThromboxane-A synthase(Rat)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037050(4-Phenyl-2-[(pyridin-3-ylmethyl)-amino]-benzothiaz...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
LigandPNGBDBM50037042(4-Methyl-2-[(pyridin-3-ylmethyl)-amino]-naphtho[1,...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetThromboxane-A synthase(Rat)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037049(4,5,7-Trimethyl-2-[(pyridin-3-ylmethyl)-amino]-ben...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetThromboxane-A synthase(Rat)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037043(2-Ethylamino-4,5-dimethyl-7-pyridin-3-ylmethyl-ben...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetThromboxane-A synthase(Rat)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037042(4-Methyl-2-[(pyridin-3-ylmethyl)-amino]-naphtho[1,...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetThromboxane-A synthase(Rat)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037052(4,7-Dimethyl-2-[(pyridin-3-ylmethyl)-amino]-benzot...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetThromboxane-A synthase(Rat)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037047(2-Amino-4,5-dimethyl-7-pyridin-3-ylmethyl-benzothi...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetThromboxane-A synthase(Rat)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037036(5,7-Dimethoxy-2-[(pyridin-3-ylmethyl)-amino]-benzo...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
LigandPNGBDBM50037050(4-Phenyl-2-[(pyridin-3-ylmethyl)-amino]-benzothiaz...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed