Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50005260
TargetDNA primase(HHV-1)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50034949(2-Amino-6-(3,5-dichloro-phenylamino)-3H-pyrimidin-...)
Affinity DataIC50: 770nMAssay Description:Inhibition against DNA-Dependent GTPase activity of HSV-1 helicase-primase in HSV-1-infected CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA primase(HHV-1)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50034955(N*2*-(3,4-Dichloro-phenyl)-9H-purine-2,6-diamine |...)
Affinity DataIC50: 850nMAssay Description:Inhibition against DNA-Dependent GTPase activity of HSV-1 helicase-primase in HSV-1-infected CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA primase(HHV-1)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50034950(2-Amino-6-(3,4-dichloro-phenylamino)-3H-pyrimidin-...)
Affinity DataIC50: 850nMAssay Description:Inhibition against DNA-Dependent GTPase activity of HSV-1 helicase-primase in HSV-1-infected CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA primase(HHV-1)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50013091(CHEMBL51613 | 2-(3,4-Dichloro-phenylamino)-1,9-dih...)
Affinity DataIC50: 880nMAssay Description:Inhibition against DNA-Dependent GTPase activity of HSV-1 helicase-primase in HSV-1-infected CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA primase(HHV-1)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50034947(2-(3,5-Dichloro-phenylamino)-1,9-dihydro-purin-6-o...)
Affinity DataIC50: 910nMAssay Description:Inhibition against DNA-Dependent GTPase activity of HSV-1 helicase-primase in HSV-1-infected CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA primase(HHV-1)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50034963(N*2*-(3,5-Dichloro-phenyl)-9H-purine-2,6-diamine |...)
Affinity DataIC50: 920nMAssay Description:Inhibition against DNA-Dependent GTPase activity of HSV-1 helicase-primase in HSV-1-infected CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA primase(HHV-1)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50028342(6-(3,4-Dichloro-phenylamino)-1H-pyrimidine-2,4-dio...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition against DNA-Dependent GTPase activity of HSV-1 helicase-primase in HSV-1-infected CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA primase(HHV-1)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50034952(6-(3,5-Dichloro-phenylamino)-1H-pyrimidine-2,4-dio...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition against DNA-Dependent GTPase activity of HSV-1 helicase-primase in HSV-1-infected CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA primase(HHV-1)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50034961(6-Chloro-N*4*-(3,4-dichloro-phenyl)-pyrimidine-2,4...)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition against Primase by coupled primase-DNA polymerase-I assay with the two subunit recombinant HSV-1 helicase primaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA primase(HHV-1)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50034955(N*2*-(3,4-Dichloro-phenyl)-9H-purine-2,6-diamine |...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition against Primase by coupled primase-DNA polymerase-I assay with the two subunit recombinant HSV-1 helicase primaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase alpha catalytic subunit(Human)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50013091(CHEMBL51613 | 2-(3,4-Dichloro-phenylamino)-1,9-dih...)
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition against DNA polymerase by direct assay with activated DNA and 25 uM dNTPs lacking the expected competitor substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase alpha catalytic subunit(Human)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50013091(CHEMBL51613 | 2-(3,4-Dichloro-phenylamino)-1,9-dih...)
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition against DNA polymerase by direct assay with activated DNA and 25 uM dNTPs lacking the expected competitor substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA primase(HHV-1)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50013091(CHEMBL51613 | 2-(3,4-Dichloro-phenylamino)-1,9-dih...)
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibition against Primase by coupled primase-DNA polymerase-I assay with the two subunit recombinant HSV-1 helicase primaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase alpha catalytic subunit(Human)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50034955(N*2*-(3,4-Dichloro-phenyl)-9H-purine-2,6-diamine |...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition against coupled primase-DNA polymerase I assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase alpha catalytic subunit(Human)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50034955(N*2*-(3,4-Dichloro-phenyl)-9H-purine-2,6-diamine |...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition against coupled primase-DNA polymerase I assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50034955(N*2*-(3,4-Dichloro-phenyl)-9H-purine-2,6-diamine |...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition against DNA topoisomerase I by direct assay with activated DNA and 25 uM dNTPs including [3H]dTTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50034961(6-Chloro-N*4*-(3,4-dichloro-phenyl)-pyrimidine-2,4...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition against DNA topoisomerase I by direct assay with activated DNA and 25 uM dNTPs including [3H]dTTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50013091(CHEMBL51613 | 2-(3,4-Dichloro-phenylamino)-1,9-dih...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition against DNA topoisomerase I by direct assay with activated DNA and 25 uM dNTPs including [3H]dTTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase alpha catalytic subunit(Human)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50034961(6-Chloro-N*4*-(3,4-dichloro-phenyl)-pyrimidine-2,4...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition against DNA polymerase by direct assay with activated DNA and 25 uM dNTPs lacking the expected competitor substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase alpha catalytic subunit(Human)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50034961(6-Chloro-N*4*-(3,4-dichloro-phenyl)-pyrimidine-2,4...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition against DNA polymerase by direct assay with activated DNA and 25 uM dNTPs lacking the expected competitor substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed