Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50004969
TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 0.700nMAssay Description:Inhibitory concentration against CCRF-CEM leukemic cell DHFR(Dihydro folate reductase).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 6nMAssay Description:inhibitory concentration against Lactobacillus casei DHFR(Dihydro folate reductase).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 40nMAssay Description:Inhibitory concentration against recombinant human DHFR(Dihydro folate reductase).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030819(N-[4-[2-(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)ethy...)
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against Lactobacillus casei DHFR(Dihydro folate reductase).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030819(N-[4-[2-(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)ethy...)
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against Lactobacillus casei DHFR(Dihydro folate reductase).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030820((S)-2-(4-((2,4-diaminofuro[2,3-d]pyrimidin-5-yl)me...)
Affinity DataIC50: 450nMAssay Description:Inhibitory concentration against recombinant human DHFR(Dihydro folate reductase).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030820((S)-2-(4-((2,4-diaminofuro[2,3-d]pyrimidin-5-yl)me...)
Affinity DataIC50: 560nMAssay Description:inhibitory concentration against Lactobacillus casei DHFR(Dihydro folate reductase).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030819(N-[4-[2-(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)ethy...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against recombinant human DHFR(Dihydro folate reductase).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030818((S)-2-(4-{[(2,4-Diamino-furo[2,3-d]pyrimidin-5-ylm...)
Affinity DataIC50: 3.05E+4nMAssay Description:Inhibitory concentration against CCRF-CEM leukemic cell DHFR(Dihydro folate reductase).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 1.70E+5nMAssay Description:Inhibitory concentration against recombinant human TS (Thymidylate synthase).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030818((S)-2-(4-{[(2,4-Diamino-furo[2,3-d]pyrimidin-5-ylm...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory concentration against Lactobacillus casei TS (Thymidylate synthase).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030818((S)-2-(4-{[(2,4-Diamino-furo[2,3-d]pyrimidin-5-ylm...)
Affinity DataIC50: 2.00E+5nMAssay Description:inhibitory concentration against Lactobacillus casei DHFR(Dihydro folate reductase).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030820((S)-2-(4-((2,4-diaminofuro[2,3-d]pyrimidin-5-yl)me...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory concentration against Lactobacillus casei TS (Thymidylate synthase).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030818((S)-2-(4-{[(2,4-Diamino-furo[2,3-d]pyrimidin-5-ylm...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory concentration against Lactobacillus casei TS (Thymidylate synthase).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030819(N-[4-[2-(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)ethy...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory concentration against Lactobacillus casei TS (Thymidylate synthase).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030818((S)-2-(4-{[(2,4-Diamino-furo[2,3-d]pyrimidin-5-ylm...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory concentration against recombinant human DHFR(Dihydro folate reductase).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030820((S)-2-(4-((2,4-diaminofuro[2,3-d]pyrimidin-5-yl)me...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory concentration against Lactobacillus casei TS (Thymidylate synthase).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030819(N-[4-[2-(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)ethy...)
Affinity DataIC50: 2.20E+5nMAssay Description:Inhibitory concentration against recombinant human TS (Thymidylate synthase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed